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Expression of Transforming Growth Factor beta-1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection

Kim HG, Chung YH, Song BC, Kim JA, Yang SH, Lee YS, Suh DJ

  • KMID: 759514
  • Korean J Intern Med.
  • 2000 Dec;15(3):165-170.
BACKGROUND: Transforming growth factor beta-1 (TGF beta 1) has been suggested to play a role in the development, growth or progression of hepatocellular carcinoma (HCC). Genotype and serum titer of...
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Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma

Bae SH, Park YM, Yoo DG, Choi JY, Byun BH, Yang JM, Lee CD, Cha SB, Park DH, KiM BS

Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present...
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The relationship between virological characteristics of hepatitis C virus (HCV) and reactivity to the regional specific proteins of HCV

Yoon SK, Park YM, Byun BH, Bae SH, Yang JM, Ahn BM, Lee YS, Lee CD, Sun HS, Kim BS

  • KMID: 759502
  • Korean J Intern Med.
  • 2000 Jul;15(2):109-116.
BACKGROUND: Although the polyproteins of hepatitis C virus(HCV) are processed and formed in nearly equimolar amounts, individual functional proteins have a discrepancy...
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