- An integrated analysis of elbasvir/grazoprevir in Korean patients with hepatitis C virus genotype 1b infection
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Lee YJ, Heo J, Kim DY, Chung WJ, Tak WY, Kim YJ, Paik SW, Sim E, Kulasingam S, Talwani R, Haber B, Hwang P
- KMID: 2467250
- Clin Mol Hepatol.
- 2019 Dec;25(4):400-407.
- doi: 10.3350/cmh.2019.0006
BACKGROUND/AIMS: In the Republic of Korea, an estimated 231,000 individuals have chronic hepatitis C virus (HCV) infection. The aim of the present analysis was to evaluate the safety and efficacy... -
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- The Management Outcome and Expansion Strategy for Treatment of Hepatitis C Virus Infection among Persons Affected with Leprosy
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Lee MW, Park HC
- KMID: 2466492
- Korean Lepr Bull.
- 2019 Dec;52(1):51-54.
- doi: 10.33161/klb.2019.52.1.51
No abstract available. -
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- Prediction and Staging of Hepatic Fibrosis in Children with Hepatitis C Virus: A Machine Learning Approach
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Barakat NH, Barakat SH, Ahmed N
- KMID: 2457469
- Healthc Inform Res.
- 2019 Jul;25(3):173-181.
- doi: 10.4258/hir.2019.25.3.173
OBJECTIVES: The aim of this study is to develop an intelligent diagnostic system utilizing machine learning for data cleansing, then build an intelligent model and obtain new cutoff values for... -
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- Efficacy of L-carnitine on ribavirin-induced hemolytic anemia in patients with hepatitis C virus infection
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Sato S, Moriya K, Furukawa M, Saikawa S, Namisaki T, Kitade M, Kawaratani H, Kaji K, Takaya H, Shimozato , Sawada Y, Seki K, Kitagawa K, Akahane T, Mitoro A, Okura Y, Yamao J, Yoshiji H
- KMID: 2447252
- Clin Mol Hepatol.
- 2019 Mar;25(1):65-73.
- doi: 10.3350/cmh.2018.0070
BACKGROUND/AIMS: L-carnitine not only alleviates hyperammonemia and reduces muscle cramps in patients with liver cirrhosis, but also improves anemia in patients with chronic hepatitis and renal dysfunction. This study prospectively... -
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- Discussion on critical points for a tailored therapy to cure hepatitis C virus infection
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Marascio N, Quirino A, Barreca GS, Galati L, Costa C, Pisani V, Mazzitelli M, Matera G, Liberto MC, Focà A, Torti C
- KMID: 2447247
- Clin Mol Hepatol.
- 2019 Mar;25(1):30-36.
- doi: 10.3350/cmh.2018.0061
Hepatitis C virus (HCV) infects around 71 million people worldwide and in 2018 it is still a major health problem. Since 2011, anti-HCV therapy with availability of direct-acting antiviral drugs... -
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- Efficacy and Safety of Daclatasvir and Asunaprevir in Patients with Hepatitis C Virus Genotype 1b Infection on Hemodialysis
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Lee BS, Song MJ, Kwon JH, Lee TH, Jang JW, Kim SH, Lee SH, Kim HS, Kim JH, Kim SB, Ko SY, Song DS
- KMID: 2446804
- Gut Liver.
- 2019 Mar;13(2):191-196.
- doi: 10.5009/gnl18240
BACKGROUND/AIMS: We evaluated the efficacy and safety of daclatasvir (DCV) and asunaprevir (ASV) in patients with chronic hepatitis C virus (HCV) infection on hemodialysis. METHODS: We performed a single-arm, multicenter prospective... -
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- Apolipoprotein E Genotype and Expression Correlated with Hepatitis C Virus Genotype and Infection
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Park GN, Jo HJ, Kim HR, Kim MJ, Shin KA, Hong SB, Chang KS
- KMID: 2442585
- J Bacteriol Virol.
- 2019 Mar;49(1):27-38.
- doi: 10.4167/jbv.2019.49.1.27
The hepatitis C virus (HCV) is a globally prevalent human pathogen that causes persistent liver infections in most infected individuals. Several studies reported that HCV particles are enriched in apolipoprotein... -
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- Seropositivity of Hepatitis C Virus among Persons affected Leprosy in Korea
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Kim JP, Kang KH, Park JM
- KMID: 2429659
- Korean Lepr Bull.
- 2018 Dec;51(1):13-21.
- doi: 10.33161/klb.2018.51.1.13
BACKGROUND: Leprosy is a contagious chronic granulomatous disease and is a disease that is associated with defects in cellular immunity. A high prevalence of hepatitis C virus infection in leprosy... -
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- Depletion of MicroRNA-373 Represses the Replication of Hepatitis C Virus via Activation of Type 1 Interferon Response by Targeting IRF5
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Gong W, Guo X, Zhang Y
- KMID: 2426332
- Yonsei Med J.
- 2018 Dec;59(10):1181-1189.
- doi: 10.3349/ymj.2018.59.10.1181
PURPOSE: Hepatitis C virus (HCV) poses a risk of chronic liver disease and threatens a significant number of people worldwide. MicroRNAs (miRNAs) are linked to the regulation of hepatocarcinogenesis. Although... -
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- Efficacy and safety of sofosbuvir plus ribavirin for Korean patients with hepatitis C virus genotype 2 infection: A retrospective multi-institutional study
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Kim YM, Kim SB, Song IH, Lee SH, Kim HS, Lee TH, Kang YW, Kim SH, Lee BS, Chae HB, Song MJ, Jang JW, Ko SY, Lee JD
- KMID: 2428759
- Clin Mol Hepatol.
- 2018 Sep;24(3):311-318.
- doi: 10.3350/cmh.2017.0070
BACKGROUND/AIMS: Sofosbuvir plus ribavirin is a standard treatment for patients infected with chronic hepatitis C virus (HCV) genotype 2 in Korea. The purpose of this study was to examine the... -
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- Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling
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Sung PS, Lee EB, Park DJ, Lozada A, Jang JW, Bae SH, Choi JY, Yoon SK
- KMID: 2428758
- Clin Mol Hepatol.
- 2018 Sep;24(3):302-310.
- doi: 10.3350/cmh.2017.0074
BACKGROUND/AIMS: Hepatitis C virus (HCV) replicates in the peripheral blood mononuclear cells (PBMCs), leading to the production of type I interferons (IFNs). It is well known that the gene expression... -
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- IKKγ Facilitates the Activation of NF-κB by Hepatitis C Virus Core Protein
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Kang BY, Lee SY, Kim JI, Choi HJ, Joo WH, Kim DW
- KMID: 2421304
- J Bacteriol Virol.
- 2018 Sep;48(3):93-101.
- doi: 10.4167/jbv.2018.48.3.93
Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV core protein has been shown to modulate various cellular signaling pathways including the... -
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- Use of direct antiviral agents in liver transplant recipients with hepatitis C virus in Korea: 2-center experience
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Kim JM, Lee KW, Sinn DH, Choi GS, Yi NJ, Kwon CH, Suh KS, Joh JW
- KMID: 2419445
- Ann Surg Treat Res.
- 2018 Sep;95(3):147-151.
- doi: 10.4174/astr.2018.95.3.147
PURPOSE: The proportion of liver recipients with HCV is gradually increasing in Korea. Limited data are available regarding the efficacy of direct antiviral agents (DAAs) in liver transplant recipients in... -
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- Hepatitis C virus infection in chronic kidney disease: paradigm shift in management
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Kim SM, Song IH
- KMID: 2415992
- Korean J Intern Med.
- 2018 Jul;33(4):670-678.
- doi: 10.3904/kjim.2018.202
Hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is associated with increased liver-related morbidity and mortality rates, accelerated progression to end-stage renal disease, and risk of cardiovascular events.... -
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- Daclatasvir Plus Asunaprevir for the Treatment of Patients with Hepatitis C Virus Genotype 1b Infection: Real-World Efficacy, Changes in Liver Stiffness and Fibrosis Markers, and Safety
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Lee HW, Oh SR, Kim DY, Jeong Y, Kim S, Kim BK, Kim SU, Kim DY, Ahn SH, Han KH, Park JY
- KMID: 2411678
- Gut Liver.
- 2018 May;12(3):324-330.
- doi: 10.5009/gnl17298
BACKGROUND/AIMS: The treatment with daclatasvir plus asunaprevir (DCV+ASV) is associated with potent antiviral effects in patients with genotype 1b hepatitis C virus (HCV) infection. We investigated the real-world efficacy, changes... -
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- Rapid Changes in Serum Lipid Profiles during Combination Therapy with Daclatasvir and Asunaprevir in Patients Infected with Hepatitis C Virus Genotype 1b
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Chida T, Kawata K, Ohta K, Matsunaga , Ito J, Shimoyama , Yamazaki S, Noritake H, Suzuki T, Suda T, Kobayashi
- KMID: 2429075
- Gut Liver.
- 2018 Mar;12(2):201-207.
- doi: 10.5009/gnl17179
BACKGROUND/AIMS: Changes in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years. However, the clinical aspects of disturbed lipid... -
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- Recognition criteria for occupational cancers in relation to hepatitis B virus and hepatitis C virus in Korea
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Kim H, Chung YK, Kim I
- KMID: 2428573
- Ann Occup Environ Med.
- 2018 ;30(1):6.
- doi: 10.1186/s40557-018-0217-0
The goal of this study was to review the scientific basis for the recognition of occupational cancer, in relation to hepatitis viral infections in Korea. Most Hepatitis B virus (HBV)... -
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- Reactivation of Hepatitis C Virus and Its Clinical Outcomes in Patients Treated with Systemic Chemotherapy or Immunosuppressive Therapy
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Lee HL, Bae SH, Jang B, Hwang S, Yang H, Nam HC, Sung PS, Lee SW, Jang JW, Choi JY, Han NI, Song BJ, Lee JW, Yoon SK
- KMID: 2395393
- Gut Liver.
- 2017 Nov;11(6):870-877.
- doi: 10.5009/gnl16434
BACKGROUND/AIMS: According to the results of several studies, the outcome of hepatitis C virus (HCV) reactivation is not as severe as the outcome of hepatitis B virus reactivation. The aim... -
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- Meta-analysis of the Efficacy and Safety of Grazoprevir and Elbasvir for the Treatment of Hepatitis C Virus Infection
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Kang MG, Kang MJ, Ji E, Yoo BK
- KMID: 2405669
- Korean J Clin Pharm.
- 2017 Sep;27(3):150-160.
- doi: 10.24304/kjcp.2017.27.3.150
OBJECTIVE: Recently, a fixed combination of grazoprevir and elbasvir (GE) has been introduced to the arsenal of chemotherapeutics to fight against this virus. The study aimed to provide information on... -
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- Current status of hepatitis C virus infection and countermeasures in South Korea
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Jeong SH, Jang ES, Choi HY, Kim KA, Chung W, Ki M
- KMID: 2406621
- Epidemiol Health.
- 2017;39:e2017017.
- doi: 10.4178/epih.e2017017
Hepatitis C virus (HCV) infection is a major cause of liver cirrhosis, hepatocellular carcinoma, and liver-related mortality. The new antiviral drugs against HCV, direct acting antivirals, result in >90% cure... -
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