- DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain
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Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI
- KMID: 2166191
- Genomics Inform.
- 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in... -
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- The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress
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Heo JI, Lee MS, Kim JH, Lee JS, Kim J, Park JB, Lee JY, Han JA, Kim JI
- KMID: 1094155
- Exp Mol Med.
- 2006 Jun;38(3):295-301.
The inducible 70 kDa heat shock proteins (Hsp70) in mice are encoded by two almost identical genes, hsp70.1 and hsp70.3. Studies have found that only hsp70.1 is induced by hypertonic... -
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- Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins
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Hong SH, Heo JI, Kim JH, Kwon SO, Yeo KM, Bakowska-Barczak AM, Kolodziejczyk P, Ryu OH, Choi MK, Kang YH, Lim SS, Suh HW, Huh SO, Lee JY
- KMID: 2170674
- Biomol Ther.
- 2013 Jul;21(4):284-289.
Antidiabetic and beta cell-protection activities of purple corn anthocyanins (PCA) were examined in pancreatic beta cell culture and db/db mice. Only PCA among several plant anthocyanins and polyphenols showed insulin... -
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- Nitric Oxide Is an Essential Mediator for Neuronal Differentiation of Rat Primary Cortical Neuron Cells
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Oh SJ, Heo JI, Kho YJ, Kim JH, Kang HJ, Park SH, Kim HS, Shin JY, Kim MJ, Kim SC, Park JB, Kim J, Lee JY
- KMID: 1460704
- Exp Neurobiol.
- 2010 Sep;19(2):83-89.
- doi: 10.5607/en.2010.19.2.83
Nitric oxide (NO) regulates proliferation, differentiation and survival of neurons. Although NO is reported to involve in NGF-induced differentiation of PC12 cells, the role of NO has not been characterized... -
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