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Helicobacter pylori in Human Stomach: Can It Be Called Mutualism or a Disease?

Cheung DY, Kim TH

Helicobacter pylori (H. pylori) has been a major concern as a gastric pathogen with unique features since discovered in the end of the 20th century. Recent data on comparative genome...
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Immune Response and the Tumor Microenvironment: How They Communicate to Regulate Gastric Cancer

Lee K, Hwang H, Nam KT

  • KMID: 1774539
  • Gut Liver.
  • 2014 Mar;8(2):131-139.
Gastric cancer is the second most common cause of cancer-related death in the world. A growing body of evidence indicates that inflammation is closely associated with the initiation, progression, and...
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The Effect of the Repeated Subcultures of Helicobacter pylori on Adhesion, Motility, Cytotoxicity, and Gastric Inflammation

Kim SS, Lee HS, Cho YS, Lee YS, Bhang CS, Chae HS, Han SW, Chung IS, Park DH

In vitro subcultures of bacteria can lead to genetic and phenotypic changes. This study aimed at investigating the effect of repeated subcultures on the adhesion, motility, cytotoxicity, and gastric inflammation...
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Antigenic diversity and serotypes of Helicobacter pylori associated with peptic ulcer diseases

Park SM, Hong SI, Jung HY, Yang SK, Kim HR, Min YI, Hong WS

  • KMID: 759071
  • Korean J Intern Med.
  • 1998 Jul;13(2):104-109.
OBJECTIVES: Clinical presentation of Helicobacter pylori (H. pylori) infection has marked variation mainly due to the strain diversity and host susceptibility. Although H. pylori is identified as a major risk...
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Jak1/Stat3 Is an Upstream Signaling of NF-kappaB Activation in Helicobacter pylori-Induced IL-8 Production in Gastric Epithelial AGS Cells

Cha B, Lim JW, Kim H

Helicobacter pylori (H. pylori) induces the activation of nuclear factor-kB (NF-kappaB) and cytokine expression in gastric epithelial cells. The Janus kinase/signal transducers and activators of transcription (Jak/Stat) cascade is the...
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alpha-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-kappaB in H. pylori-Infected Gastric Epithelial AGS Cells

Choi JH, Cho SO, Kim H

The epithelial cytokine response, associated with reactive oxygen species (ROS), is important in Helicobacter pylori (H. pylori)-induced inflammation. H. pylori induces the production of ROS, which may be involved in...
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