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Trends in Heart Valve Surgery in Korea: A Report from the Heart Valve Surgery Registry Database

Choi JW, Kim JB, Jung YJ, Hwang HY, Kim KH, Yoo JS, Lee S, Lee SH, Sung K, Je HG, Lim MH, Chang BC, Hong SC, Lee H, Shin YC, Kim JH, Lim C

Background: In this study, we present recent trends in heart valve surgery in Korea through analyses of data from the Korea Heart Valve Surgery Registry (KHVSR). Methods: We enrolled 8,981 patients...
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Challenges in Perioperative Animal Care for Orthotopic Implantation of Tissue-Engineered Pulmonary Valves in the Ovine Model

Hussein HA, Hussein HA, Sircuta C, Cotoi OS, Movileanu I, Nistor D, Cordos B, Deac R, Suciu H, Brinzaniuc K, Simionescu DT, Harpa MM

BACKGROUND: Development of valvular substitutes meeting the performance criteria for surgical correction of congenital heart malformations is a major research challenge. The sheep is probably the most widely used animal...
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Hemodynamic Performance of Pericardial Bioprostheses in the Aortic Position

Lee H, Hwang HY, Sohn SH, Choi JW, Park JB, Kim KH, Kim KB

Background: This study was conducted to evaluate the hemodynamic performance and the incidence of prosthesis-patient mismatch (PPM) after aortic valve replacement (AVR) using bovine pericardial valves (Carpentier-Edwards Perimount Magana and...
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Histological assessment of the human heart valves and its relationship with age

Gumpangseth T, Lekawanvijit S, Mahakkanukrauh P

The human heart valves are complex anatomical structures consisting of leaflets with many supporting structures. With advancing age, the microstructure of the components of the valves can change. Knowledge and...
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Clinical Value of Cardiovascular Calcifications on Non-Enhanced, Non-ECG-Gated Chest CT

Choi TS, Yong HS, Kim C, Suh YJ

Cardiovascular calcifications can occur in various cardiovascular diseases and can serve as a biomarker for cardiovascular event prediction. Advances in CT have enabled evaluation of calcifications in cardiovascular structures not...
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Symptom Clusters and Quality of Life Changes according to Recovery Period of Patients with Heart Valve Surgery

Hwang SJ, Kang JH

PURPOSE: It is widely accepted that addressing multiple symptoms together is the preferred approach in assessment and intervention and results in reduced negative patient outcomes. Yet, there are few studies...
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Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells

Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D

The goal of this study was to test the hypothesis that stem cells, as a response to valve-specific extracellular matrix “niches” and mechanical stimuli, would differentiate into valvular interstitial cells...
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Blood Conservation Strategy during Cardiac Valve Surgery in Jehovah's Witnesses: a Comparative Study with Non-Jehovah's Witnesses

Kim TS, Lee JH, Na CY

BACKGROUND: We compared the clinical outcomes of cardiac valve surgery in adult Jehovah's Witness patients refusing blood transfusion to those in non-Jehovah's Witness patients without any transfusion limitations. METHODS: From 2005...
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Post-traumatic tricuspid regurgitation with anterior papillary muscle rupture, corrected by papillary muscle reimplantation

Lee HY, Cho SH, Kim JI

A 60-year-old male patient with blunt chest trauma was transferred to our facility because of unstable vital signs and pericardial effusion. These conditions occurred after orthopedic surgery to repair multiple...
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Valved Conduit with Glutaraldehyde-Fixed Bovine Pericardium Treated by Anticalcification Protocol

Lim HG, Kim GB, Jeong S, Kim YJ

  • KMID: 2382166
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Aug;47(4):333-343.
BACKGROUND: A preclinical study was conducted for evaluating a valved conduit manufactured with a glutaraldehyde (GA)-fixed bovine pericardium treated using an anticalcification protocol. METHODS: Bovine pericardia were decellularized, fixed with GA...
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Potential Inherited Causes of Recurrent Prosthetic Mitral Valve Thrombosis in a Pregnant Patient Suffering from Recurrent Miscarriage

Kalcik M, Gursoy MO, Karakoyun , Yesin M, Astarcioglu MA, Ozkan M

An effective anticoagulation is critical in pregnant patients with prosthetic heart valves. Inherited disorders may interfere with the coagulation cascade and may be associated with obstetrical complications as well as...
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Single and Multiple Valve Surgery in Native Valve Infective Endocarditis

Kim TS, Na CY, Oh SS, Kim JH, Yie GS, Han JW, Chae MC

  • KMID: 1967093
  • Korean J Thorac Cardiovasc Surg.
  • 2013 Aug;46(4):256-264.
BACKGROUND: Surgical treatment of infective endocarditis (IE) remains a challenge, especially in cases of multiple valve surgery. We evaluated the clinical outcomes of native valve IE and compared the outcomes...
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Surgical Management of Mechanical Valve Thrombosis: Twenty-Six Years' Experience

Ahn H, Kim KH, Kim KC, Kim CY

In the present study, the authors investigated the management of mechanical valve thrombosis (MVT). From January 1981 through March 2006, 2,908 mechanical valve replacements were performed in 2,298 patients at...
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Overexpression of Transforming Growth Factor-beta1 in the Valvular Fibrosis of Chronic Rheumatic Heart Disease

Kim L, Kim DK, Yang WI, Shin DH, Jung IM, Park HK, Chang BC

For the purpose of determining the pathogenic role of transforming growth factor-beta1 (TGF-beta1) in the mechanism of chronic rheumatic heart disease, we evaluated the expression of TGF-beta1, proliferation of myofibroblasts,...
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Long Term Clinical Results of Triple Valve Replacement

Yu SH, Hong YS, Chang BC, Kang MS, Lim SH

  • KMID: 2393726
  • Korean J Thorac Cardiovasc Surg.
  • 2005 Oct;38(10):675-679.
BACKGROUND: Clinical reports on replacement of all three (AV+MV+TV) valves are rare. MATERIAL AND METHOD: From January 1992 to December 2003, 38 patients received triple valve replacement (aortic, mitral, tricuspid) at...
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The Clinical Results of Heart Valve Replacements

Park SM, Son H, Shin J, Sohn YS, Sun K, Choi YH, Kim KT, Lee IS, Kim H, Kim HM

  • KMID: 1885843
  • Korean J Thorac Cardiovasc Surg.
  • 2005 Mar;38(3):204-213.
BACKGROUND: In spite of the improvement in the quality of artificial heart valves and surgical techniques, the incidence of the complications following valve replacement is still high. We reviewed the...
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Surgical Experience of Reconstruction of the Annular and the Intervalvular Fibrous Skeleton for Active Infective Endocarditis

Sung KI, Park PW

BACKGROUND AND OBJECTIVES: The treatment for active infective endocarditis (IE) with a paravalvular abscess results in a high morbidity and mortality. Recently, some good results with a reconstruction of the...
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Results of Surgical Management in Patients with Cardiac and Arterial Manifestations of Behcet's Syndrome

Won JY, Chang BC, Lee DY, Park SJ

  • KMID: 2062606
  • Korean J Thorac Cardiovasc Surg.
  • 2002 Jan;35(1):36-42.
BACKGROUND: To evaluate the efficiency of surgical treatment in patients with cardiac valvular and arterial involvement of Behcet's syndrome. MATERIAL AND METHOD: 12 patients underwent surgical treatment due to the...
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