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Abnormal ventricular looping and abnormal laterality of the atrial chambers are the main morphogenetic mechanisms of cardiac lesions in cultured rat embryos treated with retinoic acid

Lee YM, Kim JS, Han SY, Park KL, Jang SJ, Seo JW

To establish the early morphogenetic mechanism in retinoid induced cardiac lesions, we investigated the morphology of the heart in cultured rat embryos treated with retinoic acid (RA) at 9.0...
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Cell cycle regulators during human atrial development

Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK

  • KMID: 759076
  • Korean J Intern Med.
  • 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)...
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