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Absence of HLA-B*1502 and HLA-A*3101 Alleles in 9 Korean Patients With Antiepileptic Drug-Induced Skin Rash: A Preliminary Study

Song JS, Kang ES, Joo EY, Hong SB, Seo DW, Lee SY

There have been a number of studies about correlations between HLA genotypes in various ethnic groups and occurrence of various cutaneous adverse drug reactions, ranging in intensity from mild to...
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Association of HLA-A, B antigens with Susceptibility to Advanced Endometriosis in Koreans

Whang DH, Kim SH, Park MH, Choi YM

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue outside the uterus, causing diverse diseases, including infertility, pelvic pain, dysmenorrhea, and constipation. While there is a growing body...
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Evaluation of BioSewoom(TM) HLA-A, -B, -C PCR/SSP Kit

Cha CH, Kim MH, Chung HJ, Choi SE, Oh HB

BACKGROUND: Human leukocyte antigen (HLA) typing based on polymerase chain reaction (PCR) is rapidly replacing the conventional serological method. This study was intended to evaluate Bio- SewoomTM HLA-A, -B,...
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Allelic and Haplotypic Diversity of HLA-A, -B, -C, and -DRB1 Genes in Koreans Defined by High-resolution DNA Typing

Chung HY, Yoon JA, Han BY, Song EY, Park MH

BACKGROUND: In this study, we used high-resolution DNA typing to investigate the distribution of HLA alleles and haplotypes in Koreans. METHODS: HLA-A, -B, -C, and -DRB1 alleles were genotyped at...
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Behcet's Disease: The First Mongolian Case in Literature Showing HLA B51, MICA Gene Type *5/*6

Chung YL, Bang DS, Lee ES, Lee SN, Mok JW, Park KS

  • KMID: 2428367
  • Yonsei Med J.
  • 2003 Oct;44(5):935-938.
Behcet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but...
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Association of MICA Polymorphism with HLA-B51 and Disease Severity in Korean Patients with Behcet's Disease

Park SH, Park KS, Seo YI, Min DJ, Kim WU, Kim TG, Cho CS, Mok JW, Park KS, Kim HY

The HLA-B51 allele is known to be associated with Behcet's disease (BD) in many ethnic group. However, it has not yet been clarified whether the HLA-B51 gene itself is the...
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HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs

Park HJ, Kim YJ, Kim DH, Kim J, Park KH, Park JW, Lee JH

PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction. SJS/TEN induced by certain drug is well known to be associated with...
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