- Detection of HLA-A2 subtypes by one-dimensional isoelectric focusing patterns in Korean
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Han H, Kim TG, Rhyu MG, Chung YJ
- KMID: 1687889
- J Korean Soc Microbiol.
- 1991 Feb;26(1):117-124.
No abstract available. -
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- Relationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naive CD8+ T-Cell Precursors in HLA-A2-Transgenic Mice
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Choi YS, Lee DH, Shin EC
- KMID: 2150810
- Immune Netw.
- 2014 Aug;14(4):219-225.
- doi: 10.4110/in.2014.14.4.219
We examined the immunogenicity of H-2 class I-restricted and HLA-A2-restricted epitopes through peptide immunization of HLA-A2-transgenic mice that also express mouse H-2 class I molecules. All four of the tested... -
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- Neonatal Alloimmune Thrombocytopenia Caused by Anti-HLA-A2 Alloantibodies Determined by Luminex Single Antigen Bead Assay
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Kim Y, Oh EJ, Kim Y, Lee J, Sung IK
- KMID: 1845396
- Lab Med Online.
- 2013 Jan;3(1):45-49.
- doi: 10.3343/lmo.2013.3.1.45
Neonatal alloimmune thrombocytopenia (NAIT) occurs when maternal alloantibodies react to antigens expressed on fetal platelets, which is mainly platelet-specific alloantigen or HLA, resulting in their immune destruction. Here, we described... -
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- The study of HLA antigens in a familial Behcet? disease
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Chang HK, Kim JU
- KMID: 2202482
- J Korean Rheum Assoc.
- 2000 Mar;7(1):20-25.
OBJECTIVE: Behcet? disease (BD) is a chronic inflammatory disorder affecting several organs. The etiology of BD remains unclear, although genetic factors, infectious agents, and immune mechanisms have been studied.... -
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- Analysis of Typing in Patients with Uveitis in Korean Population
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Oh JW, Kim MH, Yoo JS, Huh W
- KMID: 2336743
- J Korean Ophthalmol Soc.
- 1999 Jan;40(1):104-109.
In order to evaluate association of particular HLA typing with certain uveitis in Korean population, HLA antigens were analyzed in 114 uneitis patients(acute anterior uveitis: 32 cases, Behcet`s disease: 25... -
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- Familial Systemic Lupus Erythematosus Developed in Two Sisters
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Park JH, Cho DY, Kim SJ, Lee SC, Won YH, Chun IK
- KMID: 2425617
- Korean J Dermatol.
- 1997 Dec;35(6):1220-1224.
The pathogenesis of systemic lupus erythematosus (SLE) appears to be multifactorial, including both genetic and environmental influences. The genetic factor of SLE is well known to have an important role... -
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- The Distribution of HLA - A * 02 Subtypes in Koreans
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Han H, Kim TG, Choi HB, Chung TJ
- KMID: 2083012
- Korean J Immunol.
- 1998 Mar;20(1):31-38.
HLA-A2 is present at high frequency in most populations, as identified by serological and biochemical means. The values of these methods are limited by their failures to discriminate the products... -
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- Association of HLA Type with Stevens-Johnson Syndrome Induced by Methazolamide Treatment
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Moon JI, Seo JH, Park CK
- KMID: 2127757
- J Korean Ophthalmol Soc.
- 2000 Oct;41(10):2241-2246.
There have been reports between Stevens-Johnson syndrome (SJS)induced by methazolamide treatment and genetic background especially in Japanese and Korean descent.We report 6 cases of SJS and the results of HLA... -
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- The Frequency of HLA Alleles in Korean Children with Aplastic Anemia and the Correlation with the Response to Immunosuppressive Treatment
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Kook H, Hwang TJ, Seo JJ, Ghim TT, Moon HN, Lee YH, Kim MK, Lee KS, Lee KC, Hwang PH, Park HJ, Park KD, Park JS, Shin HY, Ahn HS
- KMID: 2278292
- Korean J Pediatr Hematol Oncol.
- 2003 Oct;10(2):177-188.
PURPOSE: Immune pathophysiology of aplastic anemia (AA) has been indirectly inferred from responses to immunosuppressive agents. An association between AA and HLA-A2, or HLA-DR2 (its serologic split, HLA-DR15; or its... -
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- Expression of c-erbB2 and HLA-A2 in Breast Cancer Patients
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Lee HD, Koo JY, Kim DY, Jung WH, Jang YS, Park JH
- KMID: 2173609
- J Korean Breast Cancer Soc.
- 1999 Dec;2(2):152-158.
- doi: 10.4048/jkbcs.1999.2.2.152
PURPOSE: Oncogene c-erbB2 produces a transmembrane protein similar in structure to the tyrosine kinase family. Overexpression of c-erbB2 is known to lower the survival rate of breast cancer patients. c-erbB2... -
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- Reconstitution of class I MHC molecules expressed in E. coli and complexed with single antigenic peptides
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Kim J, Kim MY, Chwae YJ, Park JH
- KMID: 1081047
- J Korean Med Sci.
- 1997 Aug;12(4):280-285.
- doi: 10.3346/jkms.1997.12.4.280
The HLA-Cw3 heavy chain has been expressed at high level as insoluble protein aggregates in E. coli. The protein aggregates dissolved in strong denaturant solution were efficiently reconstituted by... -
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- Cytotoxicities of Tumor-specific T Lymphocytes Primed by Glioma Apoptotic Body-or Glioma Cell Lysate-pulsed Dendritic Cells
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Kim JT, Chung DS, Kwak SW, Han YM, Park YS, Kim MC
- KMID: 1956342
- J Korean Neurosurg Soc.
- 2005 Aug;38(2):126-131.
OBJECTIVE: The choice of tumor antigen for dendritic cell(DC)-loading has still been an unresolved problem in the DC-based vaccine strategies against malignant gliomas that has not been found well-characterized tumor... -
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- HLA, CTLA-4 and TNF-beta Gene Polymorphisms and Disease Susceptibility in Korean Children with Graves' Disease
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Song MY, Jung MH, Lee JS, Kim TG, Yang SW, Lee BC
- KMID: 2200127
- J Korean Soc Endocrinol.
- 2003 Feb;18(1):32-44.
BACKGROUND: Graves' disease(GD) is an organ-specific autoimmune disorder that is inherited as a complex trait. At present three loci, namely the human leukocyte antigen(HLA), the cytotoxic T lymphocyte antigen-4(CTLA-4) and... -
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- Direct Analysis of HBV-Specific CD8+ Lymphocyte By Tetrameric HLA-A2/core 18-27 Complex in Chronic Hepatitis B
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Lee CK, Suh JH, Cho YS, Han KH, Chung JB, Chon CY, Moon YM
- KMID: 1123163
- Korean J Hepatol.
- 2002 Jun;8(2):139-148.
BACKGROUNDS/AIMS: Hepatitis B virus(HBV) specific cytotoxic T lymphocyte (CTL) response is believed to play a major role in virus control and liver damage in chronic hepatitis B(CHB). We performed this... -
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- The Study of MHC class I Restricted CD8+ T Cell Mediated Immune Responses against Mycobacterium tuberculosis Infection: Evidence of M. tuberculosis Specific CD8+ T Cells in TB Patients and PPD+ Healthy Individuals
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Cho JE, Lee KW, Park SK, Cheon SH, Cho SN, Cho S
- KMID: 1615315
- Immune Netw.
- 2003 Sep;3(3):235-241.
- doi: 10.4110/in.2003.3.3.235
BACKGROUND: The protective immunity against tuberculosis (TB) involves both CD4+ T cells and CD8+ T cells. In our previous study, we defined four Mycobacterium tuberculosis derived peptide epitopes specific for... -
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