- The latest evidence on the impact of fatty liver on liver-related outcomes and mortality in chronic hepatitis B
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Mao X, Mak LY, Seto WK
- KMID: 2543987
- Clin Mol Hepatol.
- 2023 Jul;29(3):690-692.
- doi: 10.3350/cmh.2023.0173
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- Screening strategies for non-alcoholic fatty liver disease: a holistic approach is needed
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Kasper P, Demir M, Steffen HM
- KMID: 2541425
- Clin Mol Hepatol.
- 2023 Apr;29(2):390-393.
- doi: 10.3350/cmh.2023.0059
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- Challenges in translating clinical guidelines into real-life practice for management of hepatocellular carcinoma in Taiwan
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Chen SC
- KMID: 2541415
- Clin Mol Hepatol.
- 2023 Apr;29(2):352-354.
- doi: 10.3350/cmh.2023.0101
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- The Complementary Role of PET to Pathology in Differentiating the Primary Origin of a Malignant Skin Nodule from Liver or Lung
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Ho I, Chen S, Yip Y, Ho C
- KMID: 2539528
- Nucl Med Mol Imaging.
- 2023 Feb;57(1):38-43.
- doi: 10.1007/s13139-022-00777-z
Metastasis from unknown primary is always a challenge because finding the true primary tumor significantly affects subsequent management. We present a case of malignant abdominal wall nodule initially diagnosed as... -
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- Polyploidization of Hepatocytes: Insights into the Pathogenesis of Liver Diseases
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Kim JY, Choi H, Kim HJ, Jee Y, Noh M, Lee MO
- KMID: 2532871
- Biomol Ther.
- 2022 Sep;30(5):391-398.
- doi: 10.4062/biomolther.2022.070
Polyploidization is a process by which cells are induced to possess more than two sets of chromosomes. Although polyploidization is not frequent in mammals, it is closely associated with development... -
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- Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein
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Yu DY
- KMID: 2510422
- Lab Anim Res.
- 2020 Mar;36(1):36-45.
- doi: 10.1186/s42826-020-00037-1
The hepatitis B virus (HBV) infects approximately 240 million people worldwide, causing chronic liver disease (CLD) and liver cancer. Although numerous studies have been performed to date, unfortunately there is... -
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- Detect or not to detect very early stage hepatocellular carcinoma? The western perspective
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Yang JD
- KMID: 2467242
- Clin Mol Hepatol.
- 2019 Dec;25(4):335-343.
- doi: 10.3350/cmh.2019.0010
Very early stage hepatocellular carcinoma (HCC) is defined as a single tumor with the largest diameter of the lesion measuring 2 cm or less according to Barcelona Liver Cancer staging... -
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- Long Intergenic Non-Protein Coding RNA 665 Regulates Viability, Apoptosis, and Autophagy via the MiR-186-5p/MAP4K3 Axis in Hepatocellular Carcinoma
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Shan Y, Li P
- KMID: 2457480
- Yonsei Med J.
- 2019 Sep;60(9):842-853.
- doi: 10.3349/ymj.2019.60.9.842
PURPOSE: Long intergenic non-protein coding RNA 665 (LINC00665) plays a vital role in the development of cancer. Its function in hepatocellular carcinoma (HCC), however, remains largely unknown. MATERIALS AND METHODS: The... -
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- Long Noncoding RNA MALAT1 Regulates Hepatocellular Carcinoma Growth Under Hypoxia via Sponging MicroRNA-200a
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Zhao ZB, Chen F, Bai XF
- KMID: 2452953
- Yonsei Med J.
- 2019 Aug;60(8):727-734.
- doi: 10.3349/ymj.2019.60.8.727
PURPOSE: Hepatocellular carcinoma (HCC) is a common cancer worldwide. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA (lncRNA), has been reported to be aberrantly expressed in hypoxic cancer... -
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- Direct-acting antivirals response in hepatocellular carcinoma: Does the presence of hepatocellular carcinoma matter?
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Huang CF, Yu ML
- KMID: 2451919
- Clin Mol Hepatol.
- 2019 Jun;25(2):168-171.
- doi: 10.3350/cmh.2018.1014
During the clinical trial development of directly acting antivirals (DAAs), evidence regarding the treatment efficacy in chronic hepatitis C patients with hepatocellular carcinoma (HCC) was scarce because these patients have... -
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- Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
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Woodward C, Smith J, Acreman D, Kumar N
- KMID: 2448772
- Ann Hepatobiliary Pancreat Surg.
- 2019 May;23(2):174-177.
- doi: 10.14701/ahbps.2019.23.2.174
Illicit use of androgenic anabolic steroids (AAS) is a known problem amongst certain groups including body builders and other athletes. Use of these drugs is thought to be high in... -
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- Update on Transarterial Chemoembolization with Drug-Eluting Microspheres for Hepatocellular Carcinoma
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Nouri YM, Kim JH, Yoon HK, Ko HK, Shin JH, Gwon DI
- KMID: 2429918
- Korean J Radiol.
- 2019 Jan;20(1):34-49.
- doi: 10.3348/kjr.2018.0088
Conventional transcatheter arterial chemoembolization (c-TACE) is a widely used first-line palliative treatment for patients with unresectable hepatocellular carcinoma (HCC). Despite the effectiveness of c-TACE, to date, technique and procedure scheduling... -
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- Current Status of Laparoscopic Liver Resection: Experiences from Tertiary Center
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Periyasamy M, Han HS, Cho JY, Yoon YS, Choi YR, Jang JS, Kwon SU, Kim S, Choi JK, Guro H
- KMID: 2414838
- J Minim Invasive Surg.
- 2017 Dec;20(4):125-128.
- doi: 10.7602/jmis.2017.20.4.125
Laparoscopic liver resection has been widely accepted nowadays for selective cases of liver diseases. Laparoscopic left lateral sectionectomy and minor LLR are considered standard practice worldwide and cautious introduction of... -
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- Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
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Kang D, Han Z, Oh GH, Joo Y, Choi HJ, Song JJ
- KMID: 2418924
- Yonsei Med J.
- 2017 Sep;58(5):899-909.
- doi: 10.3349/ymj.2017.58.5.899
PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism... -
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- Optimized Performance of FlightPlan during Chemoembolization for Hepatocellular Carcinoma: Importance of the Proportion of Segmented Tumor Area
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Joo SM, Kim YP, Yum TJ, Eun NL, Lee D, Lee KH
- KMID: 2458070
- Korean J Radiol.
- 2016 Oct;17(5):771-778.
- doi: 10.3348/kjr.2016.17.5.771
OBJECTIVE: To evaluate retrospectively the clinical effectiveness of FlightPlan for Liver (FPFL), an automated tumor-feeding artery detection software in cone-beam CT angiography (CBCTA), in identifying tumor-feeding arteries for the treatment... -
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- Establishment of Animal Models with Orthotopic Hepatocellular Carcinoma
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Lee TK, Na KS, Kim J, Jeong HJ
- KMID: 2313191
- Nucl Med Mol Imaging.
- 2014 Sep;48(3):173-179.
- doi: 10.1007/s13139-014-0288-y
Hepatocellular carcinoma (HCC) is one of the most serious health problems worldwide. Many researchers have investigated HCC at the level of genes, ribonucleic acid, proteins, cells, and animals. The resultant... -
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- Transcatheter Arterial Chemoembolization for Infiltrative Hepatocellular Carcinoma: Clinical Safety and Efficacy and Factors Influencing Patient Survival
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Han K, Kim JH, Yoon HM, Kim EJ, Gwon DI, Ko GY, Yoon HK, Ko HK
- KMID: 1731050
- Korean J Radiol.
- 2014 Aug;15(4):464-471.
- doi: 10.3348/kjr.2014.15.4.464
OBJECTIVE: To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) in patients with infiltrative hepatocellular carcinoma (HCC) and to identify the prognostic factors associated with patient survival. MATERIALS AND... -
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- In Vitro Radionuclide Therapy and In Vivo Scintigraphic Imaging of Alpha-Fetoprotein-Producing Hepatocellular Carcinoma by Targeted Sodium Iodide Symporter Gene Expression
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Kim KI, Lee YJ, Lee TS, Song I, Cheon GJ, Lim SM, Chung JK, Kang JH
- KMID: 1427701
- Nucl Med Mol Imaging.
- 2013 Mar;47(1):1-8.
PURPOSE: This study aimed to develop a gene expression targeting method for specific imaging and therapy of alpha-fetoprotein (AFP)-producing hepatocellular carcinoma (HCC) cells, using an adenovirus vector containing the human... -
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- Current Status of Laparoscopic Liver Resection in Korea
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Park JS, Han HS, Hwang DW, Yoon YS, Cho JY, Koh YS, Kwon CH, Kim KS, Kim SB, Kim YH, Kim HC, Chu CW, Lee DS, Kim HJ, Park SJ, Han SS, Song TJ, Ahn YJ, Yoo YK, Yu HC, Yoon DS, Lee MK, Lee HK, Min SK, Jeong CY, Hong SC, Choi IS, Hur KY
- KMID: 2157921
- J Korean Med Sci.
- 2012 Jul;27(7):767-771.
- doi: 10.3346/jkms.2012.27.7.767
Since laparoscopic liver resection was first introduced in 2001, Korean surgeons have chosen a laparoscopic procedure as one of the treatment options for benign or malignant liver disease. We distributed... -
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- Novel EGFR-TK Inhibitor EKB-569 Inhibits Hepatocellular Carcinoma Cell Proliferation by AKT and MAPK Pathways
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Kim H, Lim HY
- KMID: 1786011
- J Korean Med Sci.
- 2011 Dec;26(12):1563-1568.
- doi: 10.3346/jkms.2011.26.12.1563
Epidermal growth factor receptor (EGFR)-targeted therapies have been effective in some cancers, but not in hepatocellular carcinoma (HCC). The aim of this study was to investigate the drug potential to... -
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