- Seroreversion and Acute Decompensation in Chronic Hepatitis B after Discontinuation of Oral Nucleotide Analog in the Patients Achieving HBsAg Loss
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Cho HJ, Shin SK, Kwon OS, Kim JH, Kim YS
- KMID: 2508876
- Korean J Gastroenterol.
- 2020 Nov;76(5):256-260.
- doi: 10.4166/kjg.2020.111
Although rare patients with chronic hepatitis B can achieve HBsAg loss on oral nucleos(t)ide analog (NA), the optimal timing of stopping oral NAs safely has been considered when HBsAg and... -
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- Result Patterns and Characteristics of HBeAg and HBV DNA in Patients with Chronic Hepatitis B
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Choi EJ, Kim JH, Han MS
- KMID: 2458680
- Lab Med Online.
- 2019 Oct;9(4):210-217.
- doi: 10.3343/lmo.2019.9.4.210
BACKGROUND: Discrepancies in the results between hepatitis B e-antigen (HBeAg) and hepatitis B virus (HBV) DNA levels pose difficulties in the management of chronic hepatitis B (CHB). This study aims... -
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- Analysis of Reentry Test for the Donors Showing Reactivity or Grey Zone in a HBV Surface Antigen Assay by a Chemiluminescent Immunoassay
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Shin S, Kang J, Lee KR, Shin GS, Kang JW, Seo YI, Min H
- KMID: 2435624
- Korean J Blood Transfus.
- 2018 Dec;29(3):301-309.
- doi: 10.17945/kjbt.2018.29.3.301
BACKGROUND: If donors who were deferred due to the reactivity or grey zone in HBV surface antigen (HBsAg) assay want to donate blood again, they need to pass reentry tests.... -
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- Development of a Rapid Automated Fluorescent Lateral Flow Immunoassay to Detect Hepatitis B Surface Antigen (HBsAg), Antibody to HBsAg, and Antibody to Hepatitis C
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Ryu JH, Kwon M, Moon JD, Hwang MW, Lee JM, Park KH, Yun SJ, Bae HJ, Choi A, Lee H, Jung B, Jeong J, Han K, Kim Y, Oh EJ
- KMID: 2429124
- Ann Lab Med.
- 2018 Nov;38(6):578-584.
- doi: 10.3343/alm.2018.38.6.578
BACKGROUND: Accurate, rapid, and cost-effective screening tests for hepatitis B virus (HBV) and hepatitis C virus (HCV) infection may be useful in laboratories that cannot afford automated chemiluminescent immunoassays (CLIAs).... -
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- New perspectives of biomarkers for the management of chronic hepatitis B
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Lin CL, Kao JH
- KMID: 2373145
- Clin Mol Hepatol.
- 2016 Dec;22(4):423-431.
- doi: 10.3350/cmh.2016.0069
With recent advances in molecular and genomic investigations, the impact of hepatitis B viral and host factors on the progression of chronic HBV infection has been explored. For viral factors,... -
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- Results of Proficiency Tests for HBsAg and Anti-HCV as the Blood Donor Screening Testing (2012~2015)
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Lee MN, Kim JN, Cha YJ, Park QE, Kim HO, Kwon GC, Choi YS, Kwon JR
- KMID: 2368789
- Korean J Blood Transfus.
- 2016 Dec;27(3):265-273.
- doi: 10.17945/kjbt.2016.27.3.265
BACKGROUND: Donor screening test is one of the most important processes for blood safety management. Korea Center for Disease Control and Prevention (KCDC) has been conducting an annual proficiency test... -
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- Prevalence of Hepatitis B Virus and HIV Co-infection in Korea
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Lee HH, Hong HG, Son JS, Kwon SM, Lim BG, Lee KB, Kim GH
- KMID: 2366874
- J Bacteriol Virol.
- 2016 Dec;46(4):283-287.
- doi: 10.4167/jbv.2016.46.4.283
Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) have a common route like sexually transmitted infections (STIs), vertical transmission and blood transfusion, etc. Therefore, it was necessary to be... -
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- Increasing the Efficiency of Laboratory Performance by Using the Onboard Dilution Algorithm of the Elecsys Hepatitis B Surface Antigen II Quantitative Assay
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Sohn JY, Oh EJ, Kim HS, Park HD, Kang ES
- KMID: 2200402
- J Lab Med Qual Assur.
- 2014 Dec;36(4):196-204.
- doi: 10.15263/jlmqa.2014.36.4.196
BACKGROUND: The Elecsys hepatitis B surface antigen (HBsAg) II quantitative assay is a newly introduced electrochemiluminescence immunoassay incorporating an initial 1:400 onboard dilution and a simple algorithm to determine HBsAg... -
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- Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers
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Kim KH, Chang HY, Park JY, Park ES, Park YK, Han KH, Ahn SH
- KMID: 2069761
- Clin Mol Hepatol.
- 2014 Sep;20(3):251-260.
- doi: 10.3350/cmh.2014.20.3.251
BACKGROUND/AIMS: Occult HBV infection can persist following HBsAg loss and be transmitted, but the virological features are not well defined. METHODS: Here we investigated 25 Korean patients who lost HBsAg during... -
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- Occult hepatitis B virus infection: clearance or disguise?
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Kim JW
- KMID: 2069760
- Clin Mol Hepatol.
- 2014 Sep;20(3):249-250.
- doi: 10.3350/cmh.2014.20.3.249
No abstract available. -
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- Risk stratification of HBV infection in Asia-Pacific region
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Kao JH
- KMID: 2069757
- Clin Mol Hepatol.
- 2014 Sep;20(3):223-227.
- doi: 10.3350/cmh.2014.20.3.223
Hepatitis B virus (HBV) infection is the major etiology of chronic liver disease worldwide and thus a global health problem, especially in Asia-Pacific region. The long-term outcomes of Asian HBV... -
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- Inactive hepatitis B surface antigen carriers and intrafamilial tramsmission: results of a 10-year study
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Demirturk , Demirdal T
- KMID: 1737599
- Clin Mol Hepatol.
- 2014 Mar;20(1):56-60.
- doi: 10.3350/cmh.2014.20.1.56
BACKGROUND/AIMS: The aims of the present study were to determine the outcomes of inactive hepatitis B virus (HBV) surface antigen (HBsAg) carriers over a 10-year study period and to elucidate... -
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- HBsAg level and clinical course in patients with chronic hepatitis B treated with nucleoside analogue: five years of follow-up data
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Kim JH, Choi YJ, Moon HW, Ko SY, Choe WH, Kwon SY
- KMID: 1730887
- Clin Mol Hepatol.
- 2013 Dec;19(4):409-416.
- doi: 10.3350/cmh.2013.19.4.409
BACKGROUND/AIMS: Quantification of the hepatitis B surface antigen (HBsAg) is increasingly used to determine the treatment response in patients with chronic hepatitis B (CHB). However, there are limited data about... -
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- Performance Evaluation of 3 Kinds of HBsAg Qualitative Assays and 2 Kinds of Quantitative Assays
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Park JS, Choi JI, Lim JH, Jung J, Lee SH, Park NH, Shin JW, Nah YW, Nam CW, Cha YJ, Kim SR
- KMID: 2053551
- Lab Med Online.
- 2013 Jul;3(3):160-168.
- doi: 10.3343/lmo.2013.3.3.160
BACKGROUND: Currently used techniques for quantitation of HBsAg often yield discordant results; therefore, development of quantitation techniques that can detect HBsAg with high accuracy has become very important. Recent advances... -
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- Performance Evaluation of Immunoassay Detection of HBsAg Mutants and Their Clinical Significance in the High Risk Groups
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Choi JI, Lim JH, Jeong J, Lee SH, Park JS, Park NH, Shin JW, Nah YW, Nam CW, Cha YJ, Kim SR
- KMID: 2312217
- Lab Med Online.
- 2013 Apr;3(2):88-96.
BACKGROUND: False negative results have been reported in the immunodetection of hepatitis B virus (HBV) because of the existence of the various mutants of the virus, causing most suppliers to... -
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- Evaluation of the VITROS 3600 Analyzer for HBsAg
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Jung YS, Lim YA
- KMID: 1424264
- Korean J Blood Transfus.
- 2013 Apr;24(1):41-47.
BACKGROUND: The VITROS 3600 (Ortho Clinical Diagnostics, Johnson & Johnson, Buckinghamshire, UK), which uses the enhanced chemiluminescence immunoassay, has recently been introduced; however, it has not been evaluated for detection... -
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- Elecsys Hepatitis B Surface Antigen Quantitative Assay: Performance Evaluation and Correlation with Hepatitis B Virus DNA during 96 Weeks of Follow-up in Chronic Hepatitis B Patients
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Lee HJ, Kim SY, Lee SM, Heo J, Kim HH, Chang CL, Lee EY, Son HC
- KMID: 2434483
- Ann Lab Med.
- 2012 Nov;32(6):420-425.
BACKGROUND: Treatment for chronic hepatitis B aims to suppress virus replication and virus sequestration in hepatocytes. Covalently closed circular (ccc) DNA is the template for transcription of viral genes and... -
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- Pretreatment serum HBsAg-to-HBV DNA ratio predicts a virologic response to entecavir in chronic hepatitis B
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Song JC, Min BY, Kim JW, Kim JY, Kim YM, Shin CM, Lee SH, Hwang JH, Jeong SH, Kim N, Lee DH
- KMID: 1792605
- Korean J Hepatol.
- 2011 Dec;17(4):268-273.
- doi: 10.3350/kjhep.2011.17.4.268
BACKGROUND/AIMS: Decay of hepatitis B surface antigen (HBsAg) titers has previously been shown to be predictive of a virologic response (VR), especially during peginterferon-alpha therapy. However, the role of HBsAg... -
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- True Hepatitis B Virus Surface Antigen Prevalence among Korean Blood Donors
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Kim MJ, Park Q
- KMID: 1442277
- Korean J Blood Transfus.
- 2011 Dec;22(3):189-197.
BACKGROUND: The sensitivity of the blood screening test is crucial to ensure blood safety. Generally the test methods with greater sensitivity tend to have lower specificity. Therefore, secondary confirmatory tests... -
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- Annual Report on External Quality Assessment in Immunoserology in Korea (2009)
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Cha YJ, Kwon SY, Kim TY, Kim JR, Kim HS, Park MH, Park SH, Park AJ, Bai JH, Son HC, Lee KS, Chae SL
- KMID: 2200548
- J Lab Med Qual Assur.
- 2010 Jun;32(1):45-68.
The followings are the results for external quality assessment (EQA) in immunoserology for 2009: Evaluation of EQA was done in 2 trials in April and November, about 99% of laboratories... -
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