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Associations of Expressions of HBcAg and HBsAg with the Histologic Activity of Liver Disease and Viral Replication

Son MS, Yoo JH, Kwon CI, Ko KH, Hong SP, Hwang SG, Park PW, Park CK, Rim KS

  • KMID: 2053358
  • Gut Liver.
  • 2008 Dec;2(3):166-173.
BACKGROUND/AIMS: Subcellular localization of hepatitis B virus (HBV) core antigen (HBcAg) and HBV surface antigen (HBsAg) is known to be related to the activity of liver disease and the level...
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Hepatitis B core antigen expression pattern predicts response to lamivudine therapy in patients with chronic hepatitis B

Shi KD, Hwang SG, Choi JH, Hwang IJ, Yoon JH, Kim KI, Kwon CI, Hong SP, Park PW, Rim KS

BACKGROUNDS/AIMS: Negative hepatitis B core antigen (HBcAg) staining in hepatocytes is indicative of viral replication by an active immune response. HBcAg is expressed mainly in the cytoplasm in patients...
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Relevancy between Liver Injury, Serum HBV-DNA, and Intrahepatic HBcAg in Young Male Chronic HBV Carriers

Kim TH, Kim YS, Yeom JJ, Cho EY, Kim HS, Kim HC, Park DS, Cho JH, Yoon GJ, Moon HB

  • KMID: 1113322
  • Korean J Gastroenterol.
  • 2004 Aug;44(2):84-92.
BACKGROUND/AIMS: Although the viral load is correlated with HBcAg, liver injury was not correlated to viral load in HBeAg positive patient. We aimed to study the inter-relationship of clinical...
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The Correlation Between The Histologic Activity and Fibrosis and The Distribution of Intrahepatic HBsAg and HBcAg in Patients With Chronic Hepatitis B

Cho KB, Sohn JH, Park KS, Kwon DY, Hwang JS, Hur JW, Ahn SH, Park SK, Kim SP

  • KMID: 2241228
  • Korean J Hepatol.
  • 2001 Dec;7(4):401-412.
BACKGROUND/AIMS: The purpose of this study was to assess the correlation between histologic activity and fibrosis and the distribution of intrahepatic hepatitis B core antigen (HBcAg) and surface antigen (HBsAg)...
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Persistent Negative Anti-Bc in Chronic Hepatitis B Virus Carrier: linical Review, HBcAg and Nucleotide Sequence of It's Epitope in HLA A2 Heterozygotes

Kim JH, Kim HC

  • KMID: 2241322
  • Korean J Hepatol.
  • 1999 Jun;5(2):105-115.
BACKGROUND/AIMS: HBcAg is the most immunogenic HBV component and anti-Bc usually persists irrespective of ongoing liver disease or clearance of the virus in human. Therefore anti-Bc is considered as the most sensitive...
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An Immunohistochemical Study of the Expression of Hepatitis B Virus Antigens and p53 in Patients with Cutaneous Vasculitis Accompaied by Hepatitis B Surface Antigen-positive Hepatopathy

Kim JW, Kim SS, Seok SM, Kim KJ, Lee CJ, Jang MK, Shin HS

  • KMID: 1548197
  • Korean J Dermatol.
  • 1999 Jan;37(1):31-37.
BACKGROUND: Cutaneous vasculitis associated with viral hepatitis seems to occur as a hypersensitivity reaction against the circulating viral antigens. Hepatitis B virus(HBV)-encoded X antigen(HBxAg) is known to participate in the...
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The Expression Rate and Pattern of HBcAg and HBsAg in the Hepatocytes According to the Histologic Activity of Cirrhosis

Jeen YM, Park C

  • KMID: 1725014
  • Korean J Pathol.
  • 1995 Oct;29(5):669-677.
Since the discovery of hepatitis B virus as one of the causes of hepatitis, liver and hepatocellular carcinoma, many hepatitis B viral markers that appear in infected individuals have been...
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The Tissue Expression of HBsAg and HBcAg in Hepatocellular Carcinoma and Peritumoral Liver

Han JY, Jung WH, Chon CY, Park CI

  • KMID: 1724713
  • Korean J Pathol.
  • 1993 Aug;27(4):371-378.
To evaluate the tissue expression rate and pattenr of HBsAg and HBcAg in tumors and peritumoral livers, an immunohistochemical study was undertaken on 47 surgically resected hepatocellular carcinomas(HCCs). The results...
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Biologic Significance of Hepatocyte Hepatitis B Core Antigen Expression in Chronic Hepatitis B Virus Infection II

Lee HK, Lee KM, Chung DK

  • KMID: 1724617
  • Korean J Pathol.
  • 1992 Aug;26(4):355-359.
Routine use of commercially available antisera against hepatitis B core antigen(HBcAg) has permitted a reevaluation of the histochemical distribution of the antigen in liver tissue. HBcAg, classically described almost exclusively...
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Expression pattern of Hepatitis B Viral Core Antigen (HBcAg) and Surface Antigen (HBsAg) in Liver of the Inactive HBsAg Carriers

Ahn HJ, Kim KH, Park YN, Kim HG, Park CI

  • KMID: 1724445
  • Korean J Pathol.
  • 1990 Jun;24(2):120-127.
To understand better the complex natural course of HBV infection, the expression patterns of HBcAg and HBsAg in the liver of 51 inactive serum HBsAg carriers (24 CPH and 27...
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Biologic Significance of Hepatocyte Hepatitis B Core Antigen Expression in Chronic Hepatitis B Virus Infection

Lee HK, Kim SH

  • KMID: 1724390
  • Korean J Pathol.
  • 1989 Sep;23(3):287-291.
To elucidate the biologic significause of hepatocyte B core antigen (HBcAg) expression and its relation to the natural course of hepatitis B virus (HBV) infection, we tried to correlate the...
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Occurrence of Hepatitis B-Virus Antigens in a Consecutive Material of 112 Liver Biopsies

Kim SP, Kim CH, Lee SS, Chung CH

  • KMID: 1724339
  • Korean J Pathol.
  • 1988 Dec;22(4):404-414.
The frequency and occurrence of HBsAg and HBcAg in 112 consecutive, HBsAg sero-positive, liver biopsies were determined using immunoperxidase staining, HBsAg and HBcAg were demonstrated in 35 (31.3%) and 71...
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