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Comparison of antigenic mutation during egg and cell passage cultivation of H3N2 influenza virus

Park YW, Kim YH, Jung HU, Jeong OS, Hong EJ, Kim H, Lee JI

PURPOSE: When influenza viruses are cultured in eggs, amino acid mutations of the hemagglutinin may occur through egg adaptation. On the other hand, when influenza viruses are cultured in animal...
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Immunogenicity of a new, inactivated canine adenovirus type 2 vaccine for dogs

Yang DK, Kim HH, Yoo JY, Ji M, Han BH, Oh S, Hyun BH

PURPOSE: We constructed a new canine adenovirus type 2 (CAV-2) vaccine candidate using the recently isolated Korean CAV-2 strain; we termed the vaccine APQA1701-40P and evaluated its safety and immunogenicity...
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Recharacterization of the Canine Adenovirus Type 1 Vaccine Strain based on the Biological and Molecular Properties

Yang DK, Kim HH, Lee EJ, Yoo JY, Yoon SS, Park J, Kim CH, Kim HR

Canine adenovirus type 1 (CAV-1) infection results in hepatitis in dogs. In this study, we investigated the biologic and genetic characteristics of the CAV-1 vaccine strain (CAV1V) to improve quality...
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Development of Actinobacillus pleuropneumoniae ApxI, ApxII, and ApxIII-specific ELISA methods for evaluation of vaccine efficiency

Jung M, Won H, Shin MK, Oh MW, Shim S, Yoon I, Yoo HS

Among various vaccines against Actinobacillus pleuropneumoniae, subunit vaccines using recombinant proteins of ApxI, ApxII, and ApxIII as vaccine antigens have shown good efficacy in terms of safety and protection. Therefore,...
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Isolation and identification of canine adenovirus type 2 from a naturally infected dog in Korea

Yang DK, Kim HH, Yoon SS, Lee H, Cho IS

Canine adenovirus type 2 (CAV-2) infection results in significant respiratory illness in dogs. Isolating and culturing CAV-2 allows for investigations into its pathogenesis and the development of vaccines and diagnostic...
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The Effect of Trimebutine on the Overlap Syndrome Model of Guinea Pigs

Hussain Z, Jung DH, Lee YJ, Park H

  • KMID: 2422856
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):669-675.
  • doi: 10.5056/jnm18049
BACKGROUND/AIMS: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) disorders and these patients frequently overlap. Trimebutine has been known to be effective in controlling FD co-existing...
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Immunoreactivity of PCNA in the Cerebellum of Developing Guinea Pig

Kim DJ, Jun Y

The investigation of the embryonic development of the cerebellum has a long history. The postnatal normal development of the cerebellum in rodents and other animals became a popular topic for...
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Locacorten Vioform Ototoxicity Upon Guinea Pig Middle Ear Application

Woods O, Saliba I

BACKGROUND AND OBJECTIVES: Locacorten Vioform (Novartis UK) is frequently prescribed for otomycosis. Its component, Clioquinol, also has anti-bacterial properties. Up to this point, its ototoxic potential has not been evaluated....
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Effects of Paroxetine on a Human Ether-a-go-go-related Gene (hERG) K⁺ Channel Expressed in Xenopus Oocytes and on Cardiac Action Potential

Hong HK, Hwang S, Jo SH

K⁺ channels are key components of the primary and secondary basolateral Cl- pump systems, which are important for secretion from the salivary glands. Paroxetine is a selective serotonin reuptake inhibitor...
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Inflammation, Impaired Motility, and Permeability in a Guinea Pig Model of Postoperative Ileus

Lee YJ, Hussain Z, Huh CW, Lee YJ, Park H

  • KMID: 2417282
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):147-158.
  • doi: 10.5056/jnm17012
BACKGROUND/AIMS: Postoperative ileus (POI) is characterized by impaired propulsive function of the gastrointestinal tract after surgery. Although inflammation is considered to be an important pathogenesis of POI, significant data are...
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Inhibitory effects of 2,6-di-tert-butyl-4-hydroxymethylphenol on asthmatic responses to ovalbumin challenge in conscious guinea pigs

Jeong SY, Lee JY

This study evaluated the anti-asthmatic activities of 2,6-di-tert-butyl-4-hydroxymethylphenol (DBHP) that is a potent phenolic antioxidant in edible vegetable oil. The effects of DBHP on bronchial asthma were evaluated by determining...
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The Effect of Deoxycholic Acid on Secretion and Motility in the Rat and Guinea Pig Large Intestine

Kim NH, Park JH, Park JS, Joung YH

  • KMID: 2395430
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):606-615.
  • doi: 10.5056/jnm16201
BACKGROUND/AIMS: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon...
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Evaluation of safety and immunogenicity of a new octavalent inactivated vaccine containing porcine parvovirus, erysipelas, and leptospira

Kim K, Choi JY, Park SJ, Hahn TW

Porcine parvovirus, Erysipelothrix (E.) rhusiopathiae, and Leptospira (L.) interrogans are considered major etiologic agents of reproductive failure in pigs, causing economic loss in the swine industry. In this study, the...
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Antibacterial activity of essential oil from lavender (Lavandula angustifolia) against pet turtle-borne pathogenic bacteria

Hossain S, Heo H, De Silva B, Wimalasena SHMP, Pathirana , Heo GJ

Pet turtles are well-known to harbor an array of bacterial pathogens which can cause zoonotic infections in humans as well as opportunistic infections in the turtles itself. Essential oils are...
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Histological study on the effect of nicotine on adult male guinea pig thin skin

Eltony SA, Ali SS

Tobacco smoking has been identified as an important factor in premature skin aging to detect the histological changes occurred in adult male guinea pig thin skin under the influence of...
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The Effect of Peripheral CRF Peptide and Water Avoidance Stress on Colonic and Gastric Transit in Guinea Pigs

Hussain Z, Kim HW, Huh CW, Lee YJ, Park H

Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) diseases; however, there is frequent overlap between FD and IBS patients. Emerging evidence links the activation of corticotropin...
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Antimicrobial property of lemongrass (Cymbopogon citratus) oil against pathogenic bacteria isolated from pet turtles

De Silva B, Jung WG, Hossain S, Wimalasena S, Pathirana , Heo GJ

The usage of essential oils as antimicrobial agents is gaining attention. Besides, pet turtles were known to harbor a range of pathogenic bacteria while the turtle keeping is a growing...
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Clinical and Therapeutic Implications of Aeromonas Bacteremia: 14 Years Nation-Wide Experiences in Korea

Rhee JY, Jung DS, Peck KR

BACKGROUND: To elucidate the clinical presentation, antimicrobial susceptibility, and prognostic factors of monomicrobial Aeromonas bacteremia in order to determine the most effective optimal therapy. MATERIALS AND METHODS: We reviewed the medical...
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The Linear Transmission of the Vestibular Neural Information by Galvanic Vestibular Stimulation

Kim G, Lee S, Kim KS

OBJECTIVE: Growing hypotheses indicate the galvanic vestibular stimulation (GVS) as an alternative method to manage the symptoms of parkinson's disease (PD). GVS is easy and safe for use, and non-invasive....
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Sensitization to animal allergens and allergic symptoms during exposure to them in Korean veterinary researchers

Park HS, Shim J, Cho EY, Myoung C, Lee S, Kwon YJ, Lee SM, Park JW, Jeong SH, Lee SP

PURPOSE: Veterinary researchers are exposed to variable animal allergens. However, sensitization to them and allergic symptoms during exposure to them in this group are not sufficiently evaluated worldwide, especially in...
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