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The role of lipid peroxidation and glutathione on the glycochenodeoxycholic acid-induced cell death in primary cultured rat hepatocytes

Chu SH, Park WM, Lee KE, Pae YS

  • KMID: 1982598
  • Korean J Physiol Pharmacol.
  • 2000 Apr;4(2):121-127.
Intracellular accumulation of bile acids in the hepatocytes during cholestasis is thought to be pathogenic in cholestatic liver diseases. The objective of this study was to determine the role of lipid peroxidation and...
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Glycochenodeoxycholic acid induces cell death in primary cultured rat hepatocyte: Apoptosis and necrosis

Chu SH, Park WM, Lee KE, Pae YS

  • KMID: 2071559
  • Korean J Physiol Pharmacol.
  • 1999 Dec;3(6):565-570.
Intracellular accumulation of bile acids in the hepatocytes during cholestasis is thought to be pathogenic in cholestatic liver injury. Due to the detergent-like effect of the hydrophobic bile acids, hepatocellular injury has been...
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