- Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.
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Oh SI, Lee MS, Kim CI, Song KY, Park SC
- KMID: 1093597
- Exp Mol Med.
- 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in... -
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- Correlation of changes in natural killer cell activity and glutathione S-transferase placental form positive hepatocytes in diethylnitrosamine-induced rat hepatocarcinogenesis
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Lee YS, Choe GY, Kim YI, Park SH, Park IA, Lee MJ, Jang JJ
- KMID: 648076
- J Korean Med Sci.
- 1999 Apr;14(2):171-174.
- doi: 10.3346/jkms.1999.14.2.171
To evaluate the induction of preneoplastic hepatic foci in relation to natural killer cell (NK) activity, we sequentially analyzed glutathione S-transferase placental form positive (GST-P+) hepatocytes and NK activity during ... -
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- Pleckstrin homology domain of phospholipase C-gamma1 directly binds to 68-kDa neurofilament light chain
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Kim SK, Choi JH, Suh PG, Chang JS
- KMID: 1094152
- Exp Mol Med.
- 2006 Jun;38(3):265-272.
Phosphoinositide-specific phospholipase C-gamma1 (PLC-gamma1) has two pleckstrin homology (PH) domains: an amino-terminal domain (PH1) and a split PH domain (PH2). Here, we show that overlay assay of bovine brain tubulin... -
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- Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride
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Qin G, Ning Y, Su J, Shinozuka , Lotlikar P
- KMID: 755007
- Exp Mol Med.
- 1998 Dec;30(4):186-191.
The effect of carbon tetrachloride (CCl4) on aflatoxin B1 (AFB1)-induced enzyme altered hepatic foci has been examined in young male Fischer rats given AIN-76A diet. A single i.p. dose of... -
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- Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells
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Ahn BH, Min G, Bae YS, Bae YS, Min DS
- KMID: 1105277
- Exp Mol Med.
- 2006 Feb;38(1):55-62.
Elevated expression of protein casein kinase II (CKII) stimulated basal phospholipase D (PLD) activity as well as PMA-induced PLD activation in human U87 astroglioma cells. Moreover, CKII-selective inhibitor, emodin and... -
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- Cell-free expression and functional reconstitution of CALM in clathrin assembly
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Kim JA, Kim HL
- KMID: 1085745
- Exp Mol Med.
- 2001 Jun;33(2):89-94.
Clathrin-mediated vesicle formation is an essential step in the intracellular trafficking of the protein and lipid. Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicles... -
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- The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity
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Nam MK, Seong YM, Park HJ, Choi JY, Kang S, Rhim H
- KMID: 1105275
- Exp Mol Med.
- 2006 Feb;38(1):36-43.
Serine protease activity of high temperature requrement 2 (HtrA2) is essential for promoting cell death, as well as for protecting against cellular stresses. An X-ray crystallographic study described the formation... -
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- Expression of ErbB Receptor Proteins and TGF-alpha during Diethylnitrosamine-induced Hepatocarcinogenesis in the Rat Liver
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Lee TY, Kim KT, Han SY
- KMID: 760707
- Korean J Hepatol.
- 2007 Mar;13(1):70-80.
BACKGROUND/AIMS: ErbB receptor proteins are transmembrane tyrosine kinase receptors; when they are activated by interaction with ligands, they generate diverse cellular responses, especially during lesion development and progression to... -
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- Production and characterization of monoclonal antibodies against amphiphysins
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Jin YL, Kim KY, Soung NK, Shin EY, Kim EG, Kim SR
- KMID: 1085742
- Exp Mol Med.
- 2001 Jun;33(2):69-75.
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression... -
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- Expression and Localization of the Transforming Growth Factor-beta Type I receptor and Smads in Preneoplastic Lesions during Chemical Hepatocarcinogenesis in Rats
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Park DY, Lee CH, Sol MY, Suh KS, Yoon SY, Kim JW
- KMID: 648902
- J Korean Med Sci.
- 2003 Aug;18(4):510-519.
- doi: 10.3346/jkms.2003.18.4.510
Little is known about the involvement of Smad-related molecules in the regulation of the Transforming Growth Factor (TGF)-beta signaling pathway during hepatocarcinogenesis, particularly with respect to preneoplastic lesions of a... -
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