- Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice
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Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS
- KMID: 2466667
- J Nutr Health.
- 2019 Dec;52(6):529-539.
- doi: 10.4163/jnh.2019.52.6.529
PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL... -
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- Comparison of Squamous Cell Carcinoma of the Tongue between Young and Old Patients
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Choi G, Song JS, Choi SH, Nam SY, Kim SY, Roh JL, Lee BK, Cho KJ
- KMID: 2465436
- J Pathol Transl Med.
- 2019 Nov;53(6):369-377.
- doi: 10.4132/jptm.2019.09.16
BACKGROUND: The worldwide incidence of squamous cell carcinoma of the tongue (SCCOT) in young patients has been increasing. We investigated clinicopathologic features of this unique population and compared them with... -
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- Effect of lutein on methotrexate-induced oxidative lung damage in rats: a biochemical and histopathological assessment
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Mammadov R, Suleyman B, Akturan S, Cimen FK, Kurt N, Suleyman Z, Malkoc I
- KMID: 2463486
- Korean J Intern Med.
- 2019 Nov;34(6):1279-1286.
- doi: 10.3904/kjim.2018.145
BACKGROUND/AIMS: This study aimed to investigate the effect of lutein on methotrexate (MTX)-induced pulmonary toxicity in rats biochemically and histopathologically. METHODS: The rats in the MTX + lutein (MTXL, n =... -
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- Alteration of mitochondrial DNA content modulates antioxidant enzyme expressions and oxidative stress in myoblasts
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Min KH, Lee W
- KMID: 2461045
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):519-528.
- doi: 10.4196/kjpp.2019.23.6.519
Mitochondrial dysfunction is closely associated with reactive oxygen species (ROS) generation and oxidative stress in cells. On the other hand, modulation of the cellular antioxidant defense system by changes in... -
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- Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources
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Jeong TB, Kim JH, Kim SH, Lee S, Son SW, Lim Y, Cho JY, Hwang DY, Kim KS, Kwak JH, Jung YS
- KMID: 2470006
- Lab Anim Res.
- 2019 Oct;35(3):107-113.
- doi: 10.1186/s42826-019-0017-x
Acetaminophen (APAP) is the most common antipyretic analgesic worldwide. However, APAP overdose causes severe liver injury, especially centrilobular necrosis, in humans and experimental animals. At therapeutic dosage, APAP is mainly... -
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- Evaluation of Transcranial Magnetic Stimulation Efficiency in Major Depressive Disorder Patients: A Magnetic Resonance Spectroscopy Study
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Erbay MF, Zayman EP, Erbay LG, Ãœnal S
- KMID: 2462773
- Psychiatry Investig.
- 2019 Oct;16(10):745-750.
- doi: 10.30773/pi.2019.07.17.3
OBJECTIVE: Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD). This study evaluated the antidepressant effect of rTMS and examined how it affected N-asetyl aspartate... -
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- Antioxidant action of hypoxic conditioned media from adipose-derived stem cells in the hepatic injury of expressing higher reactive oxygen species
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Hong HE, Kim OH, Kwak BJ, Choi HJ, im KH, Ahn J, Kim SJ
- KMID: 2459313
- Ann Surg Treat Res.
- 2019 Oct;97(4):159-167.
- doi: 10.4174/astr.2019.97.4.159
PURPOSE: Almost all liver diseases are known to be accompanied by increased levels of reactive oxygen species (ROS), regardless of the cause of the liver disorder. However, little is known... -
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- Improvement in histology, enzymatic activity, and redox state of the liver following administration of Cinnamomum zeylanicum bark oil in rats with established hepatotoxicity
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Niknezhad , Sayad-Fathi S, Karimzadeh A, Ghorbani-Anarkooli M, Yousefbeyk F, Nasiri E
- KMID: 2459546
- Anat Cell Biol.
- 2019 Sep;52(3):302-311.
- doi: 10.5115/acb.18.180
Formaldehyde (FA) is an environmentally-available pollutant. Since the liver acts as a detoxifier in the human body, it is the first and most affected organ in individuals exposed to higher-than-normal... -
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- Oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome in a Nigerian tertiary hospital
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Enechukwu , Onuegbu AJ, Olisekodiaka MJ, Eleje GU, Ikechebelu JI, Ugboaja JO, Amah UK, Okwara JE, Igwegbe AO
- KMID: 2456829
- Obstet Gynecol Sci.
- 2019 Sep;62(5):335-343.
- doi: 10.5468/ogs.2019.62.5.335
OBJECTIVE: To determine the activities of oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome (PCOS) in Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria. METHODS: This was a... -
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- The effects of coenzyme Qâ‚â‚€ supplement on blood lipid indices and hepatic antioxidant defense system in SD rats fed a high cholesterol diet
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Kim HN, Jeon DG, Lim Y, Jang IS
- KMID: 2470112
- Lab Anim Res.
- 2019 Aug;35(2):86-93.
- doi: 10.1186/s42826-019-0013-1
A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Qâ‚â‚€ (COQ) and 1% of... -
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- Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells
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Jeong EM, Shin JW, Lim J, Kim JH, Kang H, Yin Y, Kim HM, Kim Y, Kim SG, Kang HS, Shin DM, Choi K, Kim IG
- KMID: 2465906
- Int J Stem Cells.
- 2019 Jul;12(2):367-379.
- doi: 10.15283/ijsc18151
Glutathione (GSH) is a major antioxidant in cells, and plays vital roles in the cellular defense against oxidants and in the regulation of redox signals. In a previous report, we... -
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- 7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
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Ko YH, Kim SK, Kwon SH, Seo JY, Lee BR, Kim YJ, Hur KH, Kim SY, Lee SY, Jang CG
- KMID: 2455091
- Biomol Ther.
- 2019 Jul;27(4):363-372.
- doi: 10.4062/biomolther.2018.211
Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine... -
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- Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells
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Cho SJ, Ryu JH, Surh YJ
- KMID: 2454670
- J Cancer Prev.
- 2019 Jun;24(2):112-122.
- doi: 10.15430/JCP.2019.24.2.112
BACKGROUND: NAD(P)H:quinone oxidoreductase-1 (NQO1) is a widely-distributed flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory 2-electron reductions of quinones, quinoneimines, nitroaromatics, and azo dyes. This reduces quinone levels and thereby minimizes... -
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- Supplementation with psyllium seed husk reduces myocardial damage in a rat model of ischemia/reperfusion
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Lim SH, Lee J
- KMID: 2453284
- Nutr Res Pract.
- 2019 Jun;13(3):205-213.
- doi: 10.4162/nrp.2019.13.3.205
BACKGROUND/OBJECTIVES: Myocardial infarction (MI) is caused by extensive myocardial damage attributed to the occlusion of coronary arteries. Our previous study in a rat model of ischemia/reperfusion (I/R) demonstrated that administration... -
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- Effect of glycyrrhizin on nicotine-induced behavioral disturbance of planarian, Dugesia japonica
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Kim YJ, So J, Yi YJ, Lee SM
- KMID: 2452873
- J Biomed Transl Res.
- 2019 Jun;20(2):21-29.
- doi: 10.12729/jbtr.2019.20.2.021
Nicotine is a component of tobacco products and is one of the most commonly abused substances that leads to addiction. Therefore, the present study was performed to investigate the behavioral... -
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- Various macromolecules in in vitro growth medium influence growth, maturation, and parthenogenetic development of pig oocytes derived from small antral follicles
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Lee H, Lee Y, Lee J, Lee GS, Lee ST, Lee E
- KMID: 2451642
- Korean J Vet Res.
- 2019 Jun;59(2):81-88.
- doi: 10.14405/kjvr.2019.59.2.81
This study was performed to examine the effects of various macromolecules in in vitro growth (IVG) media on the growth, maturation, and parthenogenesis (PA) of pig oocytes derived from small... -
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- Beta-carotene prevents the spermatogenic disorders induced by exogenous scrotal hyperthermia through modulations of oxidative stress, apoptosis, and androgen biosynthesis in mice
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Yon JM, Kim JS, Lin C, Park SG, Gwon LW, Lee JG, Baek IJ, Nahm SS, Nam SY
- KMID: 2451639
- Korean J Vet Res.
- 2019 Jun;59(2):59-67.
- doi: 10.14405/kjvr.2019.59.2.59
We investigated whether β-carotene (β-CA) or ellagic acid (EA), originating from various fruits and vegetables, has a preventive effect against male infertility induced by exogenous scrotal hyperthermia. ICR adult mice... -
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- Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress
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Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH
- KMID: 2447860
- Biomol Ther.
- 2019 May;27(3):327-335.
- doi: 10.4062/biomolther.2019.046
As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials... -
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- Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction
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Eltobshy S, Hussein AM, Elmileegy , Askar MH, Khater Y, Metias EF, Helal GM
- KMID: 2443608
- Korean J Physiol Pharmacol.
- 2019 May;23(3):203-217.
- doi: 10.4196/kjpp.2019.23.3.203
The present study was designed to examine the effect of heme oxygenase-1 (HO-1) induction by cobalt protoporphyrin (CoPP) on the cardiac functions and morphology, electrocardiogram (ECG) changes, myocardial antioxidants (superoxide... -
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- Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Jin Y, Baek N, Back S, Myung CS, Heo KS
- KMID: 2452068
- J Bacteriol Virol.
- 2018 Dec;48(4):156-165.
- doi: 10.4167/jbv.2018.48.4.156
Minor ginsenosides Rh1 and Rg2 were isolated from Korean red ginseng and reported to have various biological effects on anti-inflammatory and anti-stress activities. However, the effects of Rh1 and Rg2... -
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