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The renin-angiotensin system and aging in the kidney

Yoon HE, Choi BS

Aging is associated with progressive functional deterioration and structural changes in the kidney. Changes in the activity or responsiveness of the renin-angiotensin system (RAS) occur with aging. RAS changes predispose...
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Klotho and the Aging Process

Kuro-o M

The klotho gene was originally identified as a putative age-suppressing gene in mice that extends life span when overexpressed. It induces complex phenotypes resembling human premature aging syndromes when disrupted....
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Acute UV Irradiation Increases Heparan Sulfate Proteoglycan Levels in Human Skin

Jung JY, Oh JH, Kim YK, Shin MH, Lee D, Chung JH

Glycosaminoglycans are important structural components in the skin and exist as various proteoglycan forms, except hyaluronic acid. Heparan sulfate (HS), one of the glycosaminoglycans, is composed of repeated disaccharide units,...
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