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Effects of 4 Weeks Recombinant Human Growth Hormone Administration on Insulin Resistance of Skeletal Muscle in Rats

Park MJ, Jung SR, Jung HL, Craig BW, Lee CD, Kang HY

PURPOSE: Effect of recombinant human growth hormone (rhGH) administration on lipid storage, and its subsequent effect on insulin sensitivity have not yet been adequately examined. Thus, we investigated the effects...
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Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha

Qiang W, Weiqiang K, Qing Z, Pengju Z, Yi L

  • KMID: 756077
  • Exp Mol Med.
  • 2007 Aug;39(4):535-543.
Insufficient intracellular fat oxidation is an important contributor to aging-related insulin resistance, while the precise mechanism underlying is unclear. AMP-activated protein kinase (AMPK) is an important regulator of intracellular fat...
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