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Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis

Yoon YS, Ryu D, Lee MW, Hong S, Koo SH

During fasting periods, hepatic glucose production is enhanced by glucagon to provide fuels for other organs. This process is mediated via cAMP-dependent induction of the CREB regulated transcriptional coactivator (CRTC)...
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