- Immunoinformatic analysis of immunogenic B- and T-cell epitopes of MIC4 protein to designing a vaccine candidate against Toxoplasma gondii through an in-silico approach
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Ghaffari AD, Dalimi A, Ghaffarifar F, Pirestani M, Majidiani H
- KMID: 2525705
- Clin Exp Vaccine Res.
- 2021 Jan;10(1):59-77.
- doi: 10.7774/cevr.2021.10.1.59
Purpose: Toxoplasmosis, transmitted by Toxoplasma gondii, is a worldwide parasitic disease that affects approximately one-third of the world’s inhabitants. Today, there are no appropriate drugs to deter tissue cysts from... -
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- In-depth computational analysis of calcium-dependent protein kinase 3 of Toxoplasma gondii provides promising targets for vaccination
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Majidiani H, Soltani S, Ghaffari AD, Sabaghan M, Taghipour A, Foroutan M
- KMID: 2511704
- Clin Exp Vaccine Res.
- 2020 Jul;9(2):146-158.
- doi: 10.7774/cevr.2020.9.2.146
Purpose: The Toxoplasma gondii calcium-dependent protein kinase-3 (CDPK3) is a key enzyme for parasite egress, control of calcium-dependent permeabilization in parasitophorous vacuole membrane and tissue cyst formation. In this study,... -
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- Antigenic properties of dense granule antigen 12 protein using bioinformatics tools in order to improve vaccine design against Toxoplasma gondii
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Ghaffari AD, Dalimi A, Ghaffarifar F, Pirestani M
- KMID: 2511713
- Clin Exp Vaccine Res.
- 2020 Jul;9(2):81-96.
- doi: 10.7774/cevr.2020.9.2.81
Purpose: Toxoplasma gondii is an opportunistic parasite infecting all warm-blooded animals including humans. The dense granule antigens (GRAs) play an important role in parasite survival and virulence and in forming... -
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