- RbAp48 expression and neuronal damage in the gerbil hippocampus following 5 min of transient ischemia
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Park JH, Lee TK, Kim DW, Park CW, Park YE, Kim B, Lee JC, Lee HA, Won MH, Ahn JH
- KMID: 2470111
- Lab Anim Res.
- 2019 Aug;35(2):78-85.
- doi: 10.1186/s42826-019-0011-3
Histone-binding protein RbAp48 has been known to be involved in histone acetylation, and epigenetic alterations of histone modifications are closely associated with the pathogenesis of ischemic reperfusion injury. In the... -
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- Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)
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Kondo T, Yoshida S, Nagai H, Takeshita , Mino M, Morioka H, Nakajima T, Kusakabe K, Okada T
- KMID: 2417565
- J Vet Sci.
- 2018 Jul;19(4):505-511.
- doi: 10.4142/jvs.2018.19.4.505
In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet... -
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- Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging
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Lee KY, Yoo DY, Jung HY, Baek L, Lee H, Kwon HJ, Chung JY, Kang SH, Kim DW, Hwang IK, Choi JH
- KMID: 2413844
- Lab Anim Res.
- 2018 Jun;34(2):58-64.
- doi: 10.5625/lar.2018.34.2.58
In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains... -
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- Pre-treated Populus tomentiglandulosa extract inhibits neuronal loss and alleviates gliosis in the gerbil hippocampal CA1 area induced by transient global cerebral ischemia
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Park JH, Lee TK, Ahn JH, Shin BN, Cho JH, Kim IH, Lee JC, Kim JD, Lee YJ, Kang IJ, Hong S, Kim YH, Jeon YH, Lee YL, Won MH
- KMID: 2399897
- Anat Cell Biol.
- 2017 Dec;50(4):284-292.
- doi: 10.5115/acb.2017.50.4.284
The genus Populus (poplar) belonging to the Salicaceae family has been used in traditional medicine, and its several species show various pharmacological properties including antioxidant and anti-inflammatory effects. No study... -
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- Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils
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Ahn JH, Lee TK, Park JH, Cho JH, Kim IH, Lee JC, Hong S, Jeon YH, Kang IJ, Lee YJ, Won MH, Lee CH
- KMID: 2391097
- Lab Anim Res.
- 2017 Sep;33(3):237-243.
- doi: 10.5625/lar.2017.33.3.237
Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus,... -
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- Age-related change of Iba-1 immunoreactivity in the adult and aged gerbil spinal cord
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Lee KY, Kang JY, Yun JI, Chung JY, Hwang IK, Won MH, Choi JH
- KMID: 2451239
- Anat Cell Biol.
- 2017 Jun;50(2):135-142.
- doi: 10.5115/acb.2017.50.2.135
In the present study, we examined change of ionized calcium-binding adapter molecule 1 (Iba-1) in the adult and aged gerbil spinal cords. Significant change of morphological feature and neuronal cell... -
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- Mongolian Gerbil as a Novel Animal Model for Ligature-induced Periodontitis
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Jang S, Bak EJ
- KMID: 2368586
- Int J Oral Biol.
- 2016 Dec;41(4):225-230.
- doi: 10.11620/IJOB.2016.41.4.225
Inflammation from chronic and acute infections of distal organs and tissues such as periodontitis is a risk factor for atherosclerotic vascular processes. Recently, a new model of atherosclerosis with vascular... -
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- Accelerated and Exacerbated Effects of High Dietary Fat on Neuronal Damage Induced by Transient Cerebral Ischemia in the Gerbil Septum
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Cheon SH, Yan BC, Chen BH, Park JH, Ahn JH, Kim IH, Lee JC, Park YS, Kim MJ, Lee YL, Cho JH, Won MH
- KMID: 2169470
- Endocrinol Metab.
- 2014 Sep;29(3):328-335.
- doi: 10.3803/EnM.2014.29.3.328
BACKGROUND: Obesity induced by high-fat diet (HFD) is one of the most widespread metabolic disorders in current society. However, there has been little research regarding the effects of HFD-induced obesity... -
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- Neuroprotection of antioxidant enzymes against transient global cerebral ischemia in gerbils
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Lee JC, Won MH
- KMID: 1882589
- Anat Cell Biol.
- 2014 Sep;47(3):149-156.
- doi: 10.5115/acb.2014.47.3.149
Experimentally transient global cerebral ischemia using animal models have been thoroughly studied and numerous reports suggest the involvement of oxidative stress in the pathogenesis of neuronal death in ischemic lesions.... -
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- Change of peroxisome proliferator-activated receptor gamma expression pattern in the gerbil dentate gyrus after transient global cerebral ischemia
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Lee CH, Won MH
- KMID: 1882581
- Anat Cell Biol.
- 2014 Jun;47(2):111-116.
- doi: 10.5115/acb.2014.47.2.111
Peroxisome proliferator-activated receptor gamma (PPARgamma) has various actions including the regulation of adipocyte differentiation, lipid metabolism and glucose homeostasis. In the present study, we examined the changes of PPARgamma immunoreactivity... -
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- Sex Differences in Hippocampal Neuronal Sensitization by Nicotine in M. gerbils
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Hur YN, Lee J, Sohn SC, Won CG, Lee HH, Kim DH, Choi SH, Shin KH, Chun BG
- KMID: 1500234
- Korean J Physiol Pharmacol.
- 2013 Oct;17(5):405-409.
- doi: 10.4196/kjpp.2013.17.5.405
We studied the sex different nicotine effect on evoked population spike amplitudes (ePSA) and connexin (Cx) expression in the hippocampus CA1 area of gerbils. Acute doses of nicotine bitartrate (0.5... -
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- Post-ischemic Time-dependent Activity Changes of Hippocampal CA1 cells of the Mongolian Gerbils
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Won MH, Shin HC
- KMID: 1512889
- Korean J Physiol Pharmacol.
- 2007 Dec;11(6):247-251.
Changes of single unit activity of CA1 hippocampus region were investigated in anesthetized Mongolian gerbils for six days following transient ischemia. Ischemia was produced immediately before the implantation of micro-wire... -
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- The Effects of Mild Hypothermia on the Expression of the Apoptosis-related Proteins following Transient Global Ischemia in Gerbil Hippocampus
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Kim YM, Park KN, Choi SP, Hong TY, Kim SK
- KMID: 1931787
- Korean J Crit Care Med.
- 2007 Jun;22(1):30-41.
BACKGROUND: The neuroprotective mechanisms of hypothermia remain unclear. Recently, attenuation of apoptosis by hypothermia has been suggested as one of the responsible mechanisms. The aim of this study is to... -
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- Microsatellite instability in mongolian gerbils induced by Helicobacter pylori
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Park DI, Kim MK, Kim JJ, Yoo TW, Park JH, Kim HJ, Cho YK, Sohn CI, Jeon WK, Kim BI
- KMID: 2256647
- Korean J Med.
- 2006 Jul;71(1):17-23.
BACKGROUND: During Helicobacter pylori (HP) gastritis, the organisms cause an impairment of DNA repair that results in accumulation of mutations in the genome of epithelial cells and an increased risk... -
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- Immunohistochemical Study on the Distribution of the Voltage-gated Ion Channels in Gerbil Cerebellum
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Chung YH, Kim KH, Kim SS, Kim KY, Lee WB
- KMID: 1598732
- Korean J Phys Anthropol.
- 2005 Dec;18(4):323-334.
There is growing evidence that alterations in Ca2+ homeostasis may play a role in processes of brain aging and neurodegeneration. However, few have focused on voltage-gated Ca2+ channel (VGCC) subunits,... -
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- Three-dimensional Computer-aided Reconstruction of the Temporal Bone in Mongolian Gerbil
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Han DH, Won JH, Lee S, Kim HJ
- KMID: 2276509
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Nov;48(11):1323-1328.
BACKGROUND AND OBJECTIVES: The natural progress of experimentally induced diseases of the temporal bone can be more precisely observed using the 3-dimensional reconstructive technique. We therefore established a method by... -
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- Profiles of 7-kDa Stress Protein, betaAPP, Proliferating Cell Nuclear Antigen, and Glial Fibrillary Acidic Protein in the Gerbil with Focal Infarction and Combined Focal Infarction and Global Ischemia: Relation with Ischemic Tolerance
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Koo H
- KMID: 1964091
- Ewha Med J.
- 2004 Sep;27(2):93-100.
- doi: 10.12771/emj.2004.27.2.93
No abstract available in English. -
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- Effects of Calcitriol on Delayed Neuronal Damage of Hippocampus in Transient Global Ischemia Model of Mature Gerbil
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Park HJ, Koo HS, Han WS, Choi KK
- KMID: 2275533
- Korean J Pathol.
- 2003 Oct;37(5):307-315.
BACKGROUND: It is well documented that calcium ions perform a major role in neuronal degeneration in cerebrovascular disease and the other degenerative diseases, and that 1,25-dihydroxyvitamin D3 (D3) has the... -
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- Study for Reversibility of Experimental Cholesteatoma Using Mongolian Gerbil
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Park KH, Chun YM, Moon SK, Choung YH, Lee JS, Kim Y
- KMID: 2037135
- Korean J Otolaryngol-Head Neck Surg.
- 2003 May;46(5):372-380.
BACKGROUND AND OBJECTIVES: Epidermal characteristics of cholesteatoma such as invasion, migration, uncoordinated proliferation, and altered differentiation may arise as a result of defectiVe wound healing process, induction of preneoplastic transformation... -
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- Effects of L-Arginine and 7-Nitroindazole in the Gerbil Model of Global Cerebral Ischemia
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Cheon YJ, Kim SE, Kim YJ
- KMID: 2100680
- J Korean Soc Emerg Med.
- 2003 Mar;14(1):23-28.
PURPOSE: This study was performed to determine whether L-Arginine would improve or worsen the neurologic out-come after ischemic brain injury and whether 7- Nitroindazole (7-NI, inhibitors of neuronal nitric oxide... -
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