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Genetic factors associated with development of cerebral malaria and fibrotic schistosomiasis

Hirayama K

Collaborative studies have identified some genetic factors contributing to the development of severe forms of malaria and schistosomiasis. In Thailand, the TNF-alpha 5'-flanking region shows biallelic polymorphic sites at nucleotides...
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Familial Correlation and Heritability for Cardiovascular Risk Factors

Jee SH, Suh I, Won SY, Kim MY

The goal of this study was to describe the overall genetic contribution of phenotypic variation to cardiovascular disease. The study population included 7,589 family members of 1,891 families, derived from...
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Gender-Specific Associations between CHGB Genetic Variants and Schizophrenia in a Korean Population

Shin JG, Kim JH, Park CS, Kim BJ, Kim JW, Choi IG, Hwang J, Shin HD, Woo SI

PURPOSE: Schizophrenia is a devastating mental disorder and is known to be affected by genetic factors. The chromogranin B (CHGB), a member of the chromogranin gene family, has been proposed...
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The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis

Park YR, Choi SC, Lee ST, Kim KS, Chae SC, Chung HT

  • KMID: 1116200
  • Exp Mol Med.
  • 2005 Dec;37(6):553-558.
The eotaxin gene family (eotaxin, eotaxin-2 and eotaxin-3) have been implicated in the recruitment of eosinophils, basophiles and helper T (Th) 2 lymphocytes that is a central aspect of allergic...
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Relationship Between Metabolic Syndrome and Familial History of Hypertension/Stroke, Diabetes, and Cardiovascular Disease

Paek KW, Chun KH, Lee KW

This research analyzes the prevalence of metabolic syndrome (MS) in Korea and examines how the presence of a familial history of diseases related to MS, such as hypertension/stroke, cardiovascular disease,...
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Association between Toll-Like Receptor 9-1237T/C Polymorphism and the Susceptibility of Inflammatory Bowel Diseases: A Meta-Analysis

Shang J, Wang X, Wang W, Pan H, Liu S, Li L, Chen L, Xia B

PURPOSE: The -1237T/C polymorphism of the Toll-like receptor 9 (TLR9) gene has been implicated in the susceptibility of inflammatory bowel diseases (IBDs), but the results remain conflicting. We further investigated...
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The enabled homolog gene polymorphisms are associated with susceptibility and progression of childhood IgA nephropathy

Hahn WH, Suh JS, Cho BS, Kim SD

The enabled homolog gene (ENAH, hMena) is abundantly expressed in mesangial tissue, and might play an important role in inflammatory processes of IgA nephropathy (IgAN). The present study was conducted...
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