- Regulation of p53 Genes by Ferritin Light Chain: Preliminary Study
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Yi SY
- KMID: 1973943
- Ewha Med J.
- 2008 Jun;31(1):9-14.
- doi: 10.12771/emj.2008.31.1.9
No abstract available in English. -
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- Prognostic Significance of Immunohistochemical Expression of p53 Gene Product in Operable Breast Cancer
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Song HS, Do YR, Kang SH, Jeong KY, Kim YS
- KMID: 2166050
- Cancer Res Treat.
- 2006 Dec;38(4):218-223.
PURPOSE: The aim of this study was to investigate the prognostic significance of the expression of p53 gene product in operable invasive breast cancer by performing immunohistochemical analysis. MATERIALS AND... -
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- p53 Gene Mutation in Gastric Cancer Tissue
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Ku KB, Park SH, Cheong HY, Yu W, Lee MH
- KMID: 1565012
- J Korean Gastric Cancer Assoc.
- 2006 Dec;6(4):214-220.
PURPOSE: p53 is one of the most commonly mutated genes in human tumors. The aim of this study was to analyze p53 mutation in gastric cancer and its correlations with... -
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- Expression of the Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-2 Proteins with Heterozygosity of p53 Gene in Thyroid Tumors
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Kim SB, Rho YS, Ahn HY, Cho SJ, Shin HS
- KMID: 2037122
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Feb;48(2):225-233.
BACKGROUND AND OBJECTIVES: Mutations or overexpression of the p53 gene is believed to play an important role in the progression of various human malignant tumors. The type IV collagenase (matrix... -
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- The Combined Effect of Gamma Knife Irradiation and p53 Gene Transfection in Human Malignant Glioma Cell Lines
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Kim JE, Paek SH, Kim DG, Chung HT, Kim YY, Jung HW
- KMID: 1817828
- J Korean Neurosurg Soc.
- 2005 Jan;37(1):48-53.
OBJECTIVE: The purpose of this study is to elucidate in vitro responses to combined gamma knife irradiation and p53 gene transfection on human malignant glioma cell lines. METHODS: Two malignant... -
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- Human Papillomavirus Type 16, 18, and 33 Infection in Adenocarcinoma of the Uterine Cervix: Analysis of the p53 Gene Mutation and the Clincopathologic Correlation
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Suh KS, Cho SJ, Na SY, Noh HT, Nam SR
- KMID: 2073839
- Korean J Pathol.
- 2004 Oct;38(5):295-300.
BACKGROUND: Current evidence implicates specific types of the human papillomavirus (HPV) are involved in the development of cervical cancer. In HPV-negative cervical carcinomas, p53 mutation is thought to be a... -
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- The Property of p53 Gene in Cell Lines of Squamous Cell Carcinoma
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Jin Y, Moon YS, Jeong HS, Jang SI, Choi IJ
- KMID: 2224509
- Korean J Anat.
- 2004 Jun;37(3):293-299.
The mutation of p53 tumor suppressor gene is the most common genetic variation of primary malignant tumors. The occurrence, progression and reaction for medical management of cancers can be different... -
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- Clinical Significance of p53 Gene and nm23 Gene Expression in Esophageal Cancer
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Park K, Lee JH, Sa YJ, Jin U, Kwon JB, Park JG, Lee SH, Kwak MS
- KMID: 1878302
- Korean J Thorac Cardiovasc Surg.
- 2004 Mar;37(3):261-266.
BACKGROUND: Although significant progress has been made in the surgical treatment of esophageal carcinoma as well as in the detection of early stage esophageal carcinoma by diagnostic techniques, the prognosis... -
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- p53 Gene Mutation, Tumor p53 Protein Overexpression, and Serum Anti-p53 Antibody in Patients with Gastric Cancer
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Bong JG, Lee MH, Song KE, Kim T, Yu W
- KMID: 2372735
- J Korean Gastric Cancer Assoc.
- 2003 Dec;3(4):206-213.
PURPOSE: The clinical implication of p53 mutation in gastric cancer is still unclear, as shown by the discordant results that continue to be reported in the literature. MATENRIALS AND METHODS: To... -
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- Growth Suppression and Induction of Chemosensitivity in Human Gallbladder Epithelial Carcinoma Cells (GBCE) by Adenovirus-Mediated Transfer of the Wild-type p53 Gene
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Kim SB, Kim MH, Lee SK, Kim TW, Suh C, Shin JS, Park JS, Kim ES, Gong G, Lee JS, Kim WK, Kim SH
- KMID: 1972874
- Cancer Res Treat.
- 2003 Dec;35(6):521-527.
PURPOSE: Mutations in the p53 gene are reported in 50~90% of gallbladder and bile duct cancer, and have been implicated in chemoresistance. We undertook this study to determine whether the... -
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- Genetic Instability and Mutations of Mismatch Repair (MMR) and p53 Gene in Colorectal Cancers with Multiple Polyps and Sporadic Colorectal Cancers
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Chun SW, Chang SK
- KMID: 2334284
- J Korean Soc Coloproctol.
- 2002 Dec;18(6):353-362.
PURPOSE: General conceptions of carcinogenic mechanisms by recent reports are ras-p53 gene pathway in sporadic colorectal cancers (SCC), MMR gene pathway in hereditary nonpolyposis colorectal cancer (HNPCC) and APC gene... -
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- Expression of C-MYC, C-RAS, C-ERB B-2 Oncogenes and P53 Gene in Hydatidiform Mole
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Choi HS, Kim SM, Park CS
- KMID: 1980217
- Korean J Gynecol Oncol Colposc.
- 2002 Dec;13(4):336-341.
OBJECTIVE: To date early predictors for the development of persistent gestational trophoblastic disease (PGTD) after evacuation of a complete hydatidiform mole were not known. The purpose of this study was... -
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- Mutation of p53 Gene and Infection of Human Papillomavirus in Oral and Oropharyngeal Carcinoma
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Choi JS, Park SJ, Jo HC, Kim SY, Jung CW, Cho JS, Nam JH, Park CS
- KMID: 2275952
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Aug;45(8):796-804.
BACKGROUND AND OBJECTIVES: Oral and oropharyngeal squamous cell carcinomas (SCC) are diseases that are largely attributed to environmental exposure. Tobacco use and alcohol consumption are well-established risk factors. However, small... -
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- Analysis of p53 Gene Mutation in Basal Cell Carcinoma in Korean Patients
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Oh CK, Lee JH, Lim JY, Kim SJ, Kim MB, Jang HS, Kwon KS
- KMID: 2250821
- Korean J Dermatol.
- 2002 Jun;40(6):651-659.
BACKGROUND: There were few data on the gene mutations involved in the development of basal cell carcinoma(BCC) in Korean. OBJECTIVE: To gain insight into the role of p53 gene mutations of... -
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- In Vitro Effect of Liposome-mediated Combined p16 and p53 Gene Transfer to the Human Glioblastoma Cell Lines
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Kim CH, Kwon JT, Min BK, Hwang SN, Hwang DY, Choi DY
- KMID: 1955924
- J Korean Neurosurg Soc.
- 2002 Feb;31(2):152-160.
OBJECTIVE: To overcome the limitations of the single gene transfer, the authors present the results of wild-type p16 and p53 combined genes transfer in vitro to the U251MG and U373MG... -
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- Adenovirus and Lipofectin Mediated p53 Gene Transfection Efficiency in Human Cervical Cancer Cell Lines and Xenografted Nude Mouse
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Yeo KA, Jung JE, Lee HY, Lee BH, Kim TH, Cheung BS, Rho MS, Lee JM, Namkoong S, Park YS, Kim CK, Ahn WS
- KMID: 2262277
- Korean J Obstet Gynecol.
- 2001 Jun;44(6):1137-1144.
BACKGROUND: The classical treatment of the cervical cancer is surgery, radiotherapy, chemotherapy. Even though the improvement of treatment successful rate, conventional therapy has some limitations. Recent cutting edge of cancer... -
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- p53 Gene Mutation by Direct DNA Sequencing Predicts Poor Survival in Patients with Stomach Cancer
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Kim TW, Lee KH, Lee JH, Kang YK, Lee JS, Kim SH, Im SW, Kim JS, Kim J, Kim WK
- KMID: 1815300
- J Korean Cancer Assoc.
- 2000 Oct;32(5):835-843.
No abstract available. -
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- MICROSATELLITE INSTABILITY AND p53 GENE MUTATION IN ORAL SQUAMOUS CELL CARCINOMA
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Choi TH, Chung WB, Hong SH, Kim JA, Na SO, Jang HJ, Sohn YK, Kim CS, Kim JW
- KMID: 2005996
- J Korean Assoc Oral Maxillofac Surg.
- 2000 Aug;26(4):337-344.
Germ-line mutations at DNA repair loci confer susceptibility to colon cancer in hereditary non-polypopsis colorectal cancer. Somatic loss of DNA mismatch repair gene has been reported in a large variety... -
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- Modulation of Telomerase Activity by p53 Gene in KATO - III Gastric Carcinoma Cell Line
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Kim SY, Cho KS, Park JK, Kim YI, Yoon HJ
- KMID: 2175121
- J Korean Cancer Assoc.
- 1999 Dec;31(6):1112-1119.
PURPOSE: Alteration of p53 and telomerase activity may be responsible for gastric carcino- genesis. In this study, we tried to observe modulation of telomerase activity by wild type p53 in... -
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- K-ras and p53 gene mutation in endometrial hyperplasia and adenocarcinoma
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Kim HO, Lee JH, Lee IW, Han SA, Park MJ, Cho HD, Kim IS, Kim CH
- KMID: 2261537
- Korean J Obstet Gynecol.
- 1999 Oct;42(10):2192-2198.
Endometrial adenocarcinoma is the third common malignancy of female genital tract and categorized as estrogen-dependent tumor (type I) or not (type II). Type II endometrial adenocarcinoma more frequently occurs... -
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