- Genetic alterations in Wnt family of genes and their putative association with head and neck squamous cell carcinoma
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Aditya J, A. S. Smiline G, Paramasivam A, Vijayashree PJ
- KMID: 2514709
- Genomics Inform.
- 2021 Mar;19(1):e5.
- doi: 10.5808/gi.20065
Head and neck squamous cell carcinoma (HNSCC) is the most frequent type of head and neck cancer that usually arises from the mucosal surfaces of several organs including nasal cavity,... -
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- Prevalence and Clinicopathological Significance of METOverexpression and Gene Amplification in Patients withGallbladder Carcinoma
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Kim Y, Bang SS, Jee S, Park S, Shin SJ, Jang K
- KMID: 2500333
- Cancer Res Treat.
- 2020 Apr;52(2):481-491.
- doi: 10.4143/crt.2019.370
Purpose Mesenchymal epithelial transition (MET) is a proto-oncogene that encodes a heterodimeric transmembrane receptor tyrosine kinase for the hepatocyte growth factor. Aberrant MET signaling has been described in several solid tumors—especially non-small cell... -
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- Malignant transformation in a Breast Adenomyoepithelioma Caused by Amplification of c-MYC: A Common pathway to Cancer in a Rare Entity
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Febres-Aldana CA, Mejia-Mejia O, Krishnamurthy K, Mesko T, Poppiti R
- KMID: 2470885
- J Breast Cancer.
- 2020 Feb;23(1):93-99.
- doi: 10.4048/jbc.2020.23.e2
Breast adenomyoepitheliomas are composed of a biphasic proliferation of myoepithelial cells around small epithelial-lined spaces. Due to the rarity of adenomyoepitheliomas, the molecular data describing them are limited. Adenomyoepitheliomas are... -
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- HER2 Status and Its Heterogeneity in Gastric Carcinoma of Vietnamese Patient
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Phan DA, Nguyen VT, Hua TN, Ngo QD, Doan TP, Nguyen ST, Thai AT, Nguyen VT
- KMID: 2392580
- J Pathol Transl Med.
- 2017 Jul;51(4):396-402.
- doi: 10.4132/jptm.2017.04.24
BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is related to the pathogenesis and poor outcome of numerous types of carcinomas, including gastric carcinoma. Gastric cancer patients with HER2 positivity... -
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- EGFR Gene Amplification and Protein Expression in Invasive Ductal Carcinoma of the Breast
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Hwangbo W, Lee JH, Ahn S, Kim S, Park KH, Kim CH, Kim I
- KMID: 2277454
- Korean J Pathol.
- 2013 Apr;47(2):107-115.
BACKGROUND: The epidermal growth factor receptor (EGFR) is a surrogate marker for basal-like breast cancer. A recent study suggested that EGFR may be used as a target for breast cancer... -
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- Expression of c-Met Is Different along the Location and Associated with Lymph Node Metastasis of Head and Neck Carcinoma
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Choe JY, Yun JY, Nam SJ, Kim JE
- KMID: 2012050
- Korean J Pathol.
- 2012 Dec;46(6):515-522.
BACKGROUND: Activation of the c-Met pathway is involved in cancer progression and the prognosis. We aimed to identify any association of c-Met protein expression with a number of clinicopathologic variables... -
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- Genetic Analysis of Dystrophin Gene for Affected Male and Female Carriers with Duchenne/Becker Muscular Dystrophy in Korea
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Lee BL, Nam SH, Lee JH, Ki CS, Lee M, Lee J
- KMID: 1792998
- J Korean Med Sci.
- 2012 Mar;27(3):274-280.
- doi: 10.3346/jkms.2012.27.3.274
Duchenne and Becker muscular dystrophy (DMD/BMD) are X-linked recessive disorders caused by mutation in dystrophin gene. We analyzed the results of a genetic test in 29 DMD/BMD patients, their six... -
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- Clinicopathologic Implications of ALK Gene Copy Number Gain in Non-small Cell Lung Cancer
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Yoo SB, Kim H, Xu X, Sun PL, Jin Y, Paik JH, Jheon S, Lee CT, Chung JH
- KMID: 2005739
- J Lung Cancer.
- 2011 Dec;10(2):87-93.
- doi: 10.6058/jlc.2011.10.2.87
PURPOSE: The anaplastic lymphoma kinase (ALK) gene is a potential molecular target in non-small cell lung carcinoma (NSCLC). The clinicopathologic implication of a change in the ALK gene copy number... -
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- COL18A1 as the Candidate Gene for the Prognostic Marker of Breast Cancer According to the Analysis of the DNA Copy Number Variation by Array CGH
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Hwang KT, Chung JK, Jung IM, Heo SC, Ahn YJ, Ahn HS, Chang MS, Kim JA, Han W, Noh DY
- KMID: 2286558
- J Breast Cancer.
- 2010 Mar;13(1):37-45.
- doi: 10.4048/jbc.2010.13.1.37
PURPOSE: We tried to select and validate the candidate gene for the prognostic marker of breast cancer by comparing the analysis of copy number variation (CNV) between normal breast tissues... -
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- Identification of Proteolipid Protein 1 Gene Duplication by Multiplex Ligation-Dependent Probe Amplification: First Report of Genetically Confirmed Family of Pelizaeus-Merzbacher Disease in Korea
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Kim SJ, Yoon JS, Baek HJ, Suh SI, Bae SY, Cho HJ, Ki CS
- KMID: 1713470
- J Korean Med Sci.
- 2008 Apr;23(2):328-331.
- doi: 10.3346/jkms.2008.23.2.328
Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder with a prototype of a dysmyelinating leukodystrophy that is caused by a mutation in the proteolipid protein 1 (PLP1) gene on... -
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- Role of Epidermal Growth Factor Receptor and the HER-2 Gene in Hormone Refractory Prostate Cancer
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Cho KS, Kim DJ, Lee JS, Cho NH, Park K, Ham WS, Choi YD
- KMID: 2312032
- Korean J Urol.
- 2008 Jan;49(1):24-30.
PURPOSE: Amplification and mutation of the epidermal growth factor receptor(EGFR) and HER-2 genes were analyzed in the tissues of hormone refractory prostate cancer(HRPC) patients. MATERIALS AND METHODS: Gene amplifications of the... -
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