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Phlegmonous Gastritis Caused by Penetration of a Toothpick

Rim CB, Kim SM

Phlegmonous gastritis is a disease caused by a bacterial infection of the gastric wall. This condition is rare, but when it does occur, its prognosis appears to be poor. The...
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Gastric Polyp: Is It Serious?

Lee K, Kim TH

Gastric polyps are morphological diagnoses that collectively refer to various types of lesions, and are commonly found by accident in gastroscopy. Gastric polyps in the broad sense are commonly referred...
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Snakeskin Appearance of Gastric Mucosa Compressed by Adjustable Gastric Bands: A Novel Diagnostic Marker of Band Migration

Park TW, Kim SM

PURPOSE: The aim of this retrospective study is to describe changes of gastric mucosa in patients with adjustable gastric band migration, and to evaluate the diagnostic value of these changes. MATERIALS...
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Effectiveness of Helicobacter pylori Eradication before Endoscopic Resection

Ahn JY

Helicobacter pylori (H. pylori) infection can cause gastric dysplasia and cancer via chronic inflammatory changes in the gastric mucosa that may lead to gastric atrophy and intestinal metaplasia. Many epidemiologic...
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Characterization of Intraductal Papillary Neoplasm of the Bile Duct with Respect to the Histopathologic Similarities to Pancreatic Intraductal Papillary Mucinous Neoplasm

Nakanuma Y, Kakuda Y, Uesaka K

Intraductal papillary neoplasms of the bile duct (IPNBs) are known to show various pathologic features and biological behaviors. Recently, two categories of IPNBs have been proposed based on their histologic...
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Diagnosis and Management of Gastric Intestinal Metaplasia: Current Status and Future Directions

Huang RJ, Choi AY, Truong CD, Yeh MM, Hwang JH

Gastric intestinal metaplasia (GIM) is a known premalignant condition of the human stomach along the pathway to gastric cancer (GC). Histologically, GIM represents the replacement of normal gastric mucosa by...
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Helicobacter pylori Infection and the Kyoto Classification of Gastritis

Lee SY

Estimating the risk of Helicobacter pylori (H. pylori)-induced gastric cancer during endoscopic examination is important. Owing to recent advances in gastrointestinal endoscopy, the gross appearance of the background gastric mucosa...
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Blue Laser Imaging with a Small-Caliber Endoscope Facilitates Detection of Early Gastric Cancer

Takahashi , Miura Y, Osawa H, Takezawa T, Ino Y, Okada M, Lefor AK, Yamamoto H

Conventional endoscopy often misses early gastric cancers with minimal red discoloration because they cannot be distinguished from inflamed mucosa. We treated a patient with a small early gastric cancer that...
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Periodic Methylation Patterns in the Background Mucosa of Gastric Cancer

Kim SW, Oh JH, Kim TH, Kim JS, Hong SJ

BACKGROUND/AIMS: Gastrointestinal glandular stem cells renew every 8 years. New stem cells with impeded housekeeping gene methylation have unstable phenotypes and are prone to transform into malignant cells. Age-related changes...
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Are Wischnewski Spots Found Only in Hypothermia?

Noh MK, Lee S

Wischnewski spots (WS) are multiple black spots observed in the gastric mucosa at autopsy that are considered a reliable and important feature of hypothermia. Nonetheless, the frequency of WS varies...
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Gastric Mucosal Atrophy Impedes Housekeeping Gene Methylation in Gastric Cancer Patients

Oh JH, Rhyu MG, Kim SI, Yun MR, Shin JH, Hong SJ

PURPOSE: Helicobacter pylori infection induces phenotype-stabilizing methylation and promotes gastric mucosal atrophy that can inhibit CpG-island methylation. Relationship between the progression of gastric mucosal atrophy and the initiation of CpG-island...
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Meckel's Diverticulum Diagnosed in a Child with Suspected Small Bowel Crohn's Disease

Kang HS, Lee JS, Hyun CR, Jung IH, Kang KS

We report a rare case of Meckel's diverticulum in a boy who initially presented with chronic iron deficiency anemia (IDA) without any history of gastrointestinal (GI) bleeding at 8 years-old....
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Disruption of the Tff1 gene in mice using CRISPR/Cas9 promotes body weight reduction and gastric tumorigenesis

Kim H, Jeong H, Cho Y, Lee J, Nam KT, Lee HW

Trefoil factor 1 (TFF1, also known as pS2) is strongly expressed in the gastrointestinal mucosa and plays a critical role in the differentiation of gastric glands. Since approximately 50% of...
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Gastric Adenocarcinoma of Fundic Gland Type with Aggressive Transformation and Lymph Node Metastasis: a Case Report

Okumura Y, Takamatsu , Ohashi M, Yamamoto Y, Yamamoto N, Kawachi H, Ida S, Kumagai K, Nunobe S, Hiki N, Sano T

A 55-year-old man visited our hospital for a detailed examination of a gastric submucosal tumor that was first detected 10 years prior. The tumor continued to grow and had developed...
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Clinical Implication and Risk Factors for Malignancy of Atypical Gastric Gland during Forceps Biopsy

Kim MS, Kim SG, Chung H, Kim J, Hong H, Lee HJ, Kim HJ, Kim MA, Kim WH, Jung HC

BACKGROUND/AIMS: Although forceps biopsy is performed for suspicious gastric tumors during endoscopy, it is difficult to determine treatment strategies for atypical gastric glands due to uncertainty of the diagnosis. The...
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Quantitative analysis of COX-2 promoter methylation in gastric carcinoma

Kim HG, Ryu SY, Lee KH, Lee JH, Kim DY

PURPOSE: To determine the occurrence of COX-2 methylation in gastric carcinoma (GC), the status and level of CpG methylation in the promoter region of cyclooxygenase-2 (COX-2) were analyzed in early...
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Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2(/TIS21) via downregulating cytoplasmic nucleolin expression

Devanand P, Oya Y, Sundaramoorthy S, Song KY, Watanabe T, Kobayashi , Shimizu Y, Hong SA, Suganuma M, Lim IK

To understand the regulation of Helicobacter pylori (H. pylori)-associated gastric carcinogenesis, we examined the effect of B-cell translocation gene 2 (BTG2) expression on the biological activity of Tipα, an oncoprotein...
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Endoscopic Full-Thickness Resection Combined with Laparoscopic Surgery

Kim CG

Endoscopic full-thickness resection combined with laparoscopic surgery was recently developed. These procedures could be categorized as “Cut first and then suture” and “Suture first and then cut”. “Cut first and...
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Ileal Heterotopic Gastric Mucosa with Small Bowel Obstruction Mimicking Inflammatory Bowel Disease: A Case Study

Cho JY, Woo JY, Hong HS, Yang I, Moon JH, Hwang JY, Kim HM, Kim HY, Kim HJ, Kim JW

Gastric heterotopia rarely occurs in the ileum without a Meckel's diverticulum. We report a case of a 53-year-old man who presented with recurrent abdominal pain. The initial computed tomography (CT)...
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Endoscopic Treatment of Jejunal Heterotopic Gastric Mucosa that Caused Recurrent Intussusception

Ahn KR, Koo JS, Kim HI, Kim JH, Lee JH, Kim SY, Jung SW, Lee SW

Heterotopic gastric mucosa (HGM) is a rare anomaly in the small bowel and may be the cause of intussusception when it gets a lead point in the jejunum. All cases...
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