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Insulin-Like Growth Factor-1 Receptor Targeted Fluorescent Imaging for Gallbladder Cancer in Orthotopic Mouse Models

Choi JH, Park JY

Background/Aims: Gallbladder cancer is fatal, but fluorescent imaging technology can facilitate timely diagnosis and improve patient outcomes. Fluorophore-conjugated insulin-like growth factor-1 receptor (IGF-1R) targeted antibodies were used to visualize gallbladder...
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Incidental gallbladder cancer: a retrospective clinical study of 40 cases

Altiok M, Özdemir HG, Kurt F, Gul MO, Gumus S

Purpose: Cholecystectomy is one of the most common surgeries today due to gallbladder diseases. The most prevalent malignancy of the biliary tract is gallbladder cancer. We aimed to discuss the...
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Relationship between high bile juice amylase levels and chronic bacterial infections in patients with gallbladder cancer

Park YM, Seo HI, Kim S, Hong SB, Lee NK, Kim DU, Han SY, Lee SJ, Kim JR

Purpose: Pancreatic enzyme reflux into the biliary tract is associated with chronic inflammation and increased cellular proliferation in the biliary epithelium, leading to biliary carcinoma. We evaluated the relationship between...
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Upper Gastrointestinal Bleeding with Cholecystoduodenal Fistula

Seo MW

Cholecystoduodenal fistula, caused by gallbladder stone, trauma, peptic ulcer disease, and malignancy, is an uncommon cause of upper gastrointestinal hemorrhage. I report a case of cholecystoduodenal fistula with upper gastrointestinal...
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Bi-segmentectomy versus wedge hepatic resection in extended cholecystectomy for T2 and T3 gallbladder cancer: A matched case-control study

Nag HH, Nekarakanti PK, Sachan A, Nabi P, Tyagi S

Backgrounds/Aims: Extended cholecystectomy (EC) is the mainstay of treatment in most patients with potentially curable gallbladder cancer (GBC). The optimum extent of hepatic resection in EC is debatable. Methods: This retrospective...
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Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling

Choi SJ, Kim Y, Jeon J, Gwak HJ, Kim M, Kang K, Kim Y, Jeong J, Jung YK, Lee KG, Choi HS, Jung DH, Lee SG, Lee Y, Shin SJ, Jang K, Rho M, Choi D

Background: Cholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been investigated fully. We aimed to analyze the bile...
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Gallbladder polyps: evolving approach to the diagnosis and management

Kim KH

Gallbladder (GB) polyp is a mucosal projection into the GB lumen. With increasing health awareness, GB polyps are frequently found using ultrasonography during health screening. The prevalence of GB polyps...
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Association between gallstones and the risk of biliary tract cancer: a systematic review and meta-analysis

Huang D, Joo H, Song N, Cho S, Kim W, Shin A

OBJECTIVES: Biliary tract cancers (BTCs) are rare but highly fatal. Although the etiology of BTC is poorly understood, gallstones are proposed to be a major risk factor. We conducted a...
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Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

Saritas AG, Gul MO, Teke Z, Ulku A, Rencuzogullari A, Aydin I, Akcam AT

Purpose: The aim of this study was to review patients with xanthogranulomatous cholecystitis (XGC). Methods: A total of 79 patients diagnosed with XGC were included in the study. The criteria for...
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High Systemic Inflammation Response Index (SIRI) Indicates Poor Outcome in Gallbladder Cancer Patients with Surgical Resection: A Single Institution Experience in China

Sun L, Hu W, Liu M, Chen Y, Jin B, Xu H, Du S, Xu Y, Zhao H, Lu X, Sang X, Zhong S, Yang H, Mao Y

Purpose The systemic inflammation response index (SIRI) has been reported to have prognostic ability in various solid tumors but has not been studied in gallbladder cancer (GBC). We aimed to determine...
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Recent Updates on Diagnosis, Treatment, and Follow-up of Gallbladder Polyps

Jang SI, Cho JH, Lee DK

A gallbladder (GB) polyp is an elevation of the GB mucosa that protrudes into the GB lumen. GB polyps have an estimated prevalence of 0.3-9.5% and can be divided into...
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Cholelithiasis as a Risk Factor for Gallbladder Cancer

Oh DJ, Jang DK, Lee JK

Although the incidence of gallbladder cancer is relatively low, Korea is one of the countries with the highest incidences of gallbladder cancer in the world. Gallbladder cancer is also often...
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Oncologic Outcomes of Extended Lymphadenectomy without Liver Resection for T1/T2 Gallbladder Cancer

Chong JU, Lee WJ

PURPOSE: This study provides a standardized operative strategical algorithm that can be applied to patients with T1/T2 gallbladder cancer (GBC). Our aim was to determine the oncologic outcome of radical...
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Significance of Metabolic Tumor Volume and Total Lesion Glycolysis Measured Using ¹⁸F-FDG PET/CT in Locally Advanced and Metastatic Gallbladder Carcinoma

Chun YJ, Jeung HC, Park HS, Park JS, Rha SY, Choi HJ, Lee JH, Jeon TJ

PURPOSE: This study aimed to determine the prognostic value of new quantitative parameters of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT), including metabolic tumor volume (MTV), in patients with locally...
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Trends in Gallbladder Cancer Incidence and Survival in Korea

Wi Y, Woo H, Won YJ, Jang JY, Shin A

PURPOSE: The current study was undertaken to examine the trend in gallbladder cancer (GBC) incidenceand survival in Korea. MATERIALS AND METHODS: GBC incidence data by histologic typewere obtained from the Korea...
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The optimal surgical resection approach for T2 gallbladder carcinoma: evaluating the role of surgical extent according to the tumor location

Park TJ, Ahn KS, Kim YH, Kim TS, Hong JH, Kang KJ

PURPOSE: The clinical behavior of T2 gallbladder cancer varies among patients. The aims of this study were to identify prognostic factors for survival and recurrence, and to determine the optimal...
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Role of common bile duct resection in T2 and T3 gallbladder cancer patients

Lim JH, Chong JU, Kim SH, Park SW, Choi JS, Lee WJ, Kim KS

BACKGROUNDS/AIMS: Routine bile duct resection as part of the typical oncological resection for patients with advanced gallbladder cancer remains controversial with regard to, ultimately, curative value. The aim of this...
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Metastatic Gallbladder Cancer Treated with Curative Surgery after Cyclic Chemotherapy and Biliary Drainage

You MS, Lee SH, Kang J, Choi YH, Choi JH, Paik WH, Ryu JK, Kim YT

Gallbladder cancer is the most common malignancy of the biliary tract and carries very poor prognosis. Surgery is an only curative modality of treatment in the gallbladder cancer. However, as...
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Multidisciplinary Therapeutic Approach to Gallbladder Cancer

Park CH

Gallbladder cancer is the most common of all the biliary tract cancers. Incidence gradually increases with age, and women are more likely diagnosed with gallbladder cancer. Patients with gallbladder cancer...
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Epidemiology and Risk Factors of Gallbladder Cancer

Kim YS

Gallbladder cancer (GBC)t is highly fatal. Despite recent advances in diagnostic and therapeutic modalities, 5-year survival rate of patients with GBC is less than 5%. Most cases are diagnosed in...
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