- The role of the exocyst in renal ciliogenesis, cystogenesis, tubulogenesis, and development
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Lipschutz
- KMID: 2457718
- Kidney Res Clin Pract.
- 2019 Sep;38(3):260-266.
- doi: 10.23876/j.krcp.19.050
The exocyst is a highly conserved eight-subunit protein complex (EXOC1–8) involved in the targeting and docking of exocytic vesicles translocating from the trans-Golgi network to various sites in renal cells.... -
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- Mutational Analysis of the NF1 Gene in Two Families with Neurofibromatosis 1 Accompanied by Pheochromocytoma
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Yi HS, Kim SH, Kim J, Bae EJ, Hong S, Park IB, Kim YJ, Lee S
- KMID: 1497727
- Endocrinol Metab.
- 2011 Jun;26(2):177-184.
- doi: 10.3803/EnM.2011.26.2.177
Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant inherited disorders affecting the nervous system. NF1 is associated with mutations in the NF1 gene, which is located... -
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- Characterization of the Rho GTPase-Activating Protein RhoGAP68F
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Nahm M, Lee S
- KMID: 2165343
- Exp Neurobiol.
- 2011 Mar;20(1):29-34.
- doi: 10.5607/en.2011.20.1.29
Rho small GTPases control multiple aspects of neuronal morphogenesis by regulating the assembly and organization of the actin cytoskeleton. Although they are negatively regulated by GTPase activating proteins (GAPs), the... -
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- IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
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Chen F, Zhu HH, Zhou LF, Wu SS, Wang J, Chen Z
- KMID: 1104208
- Exp Mol Med.
- 2010 Jul;42(7):477-483.
- doi: 10.3858/emm.2010.42.7.049
The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had... -
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- RGS Proteins and Opioid Signaling
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Kim KS, Palmer PP, Kim KJ
- KMID: 2278010
- Korean J Pain.
- 2006 Jun;19(1):8-16.
- doi: 10.3344/kjp.2006.19.1.8
The regulators of the G protein signaling (RGS) proteins are responsible for the rapid acceleration of the GTPase-activity intrinsic to the heterotrimeric G protein alpha subunits. As GTPase-activating proteins (GAP),... -
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- In vivo determination of the gap2 gene promoter activity in Giardia lamblia
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Yang HW, Kim J, Yong TS, Park SJ
- KMID: 1091832
- Korean J Parasitol.
- 2006 Mar;44(1):21-26.
- doi: 10.3347/kjp.2006.44.1.21
A shuttle vector for Escherichia coli and Giardia lamblia was modified to produce a reporter plasmid, which monitors the expression of prescribed gene in G. lamblia by measuring its luciferase... -
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- Analysis of HPV-16 E6-related gene expression using cDNA microarray
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Myeong J, Rha SY, Lee MJ, Um SJ, Namkoong S, Park JS
- KMID: 2270643
- Korean J Obstet Gynecol.
- 2002 Dec;45(12):2280-2288.
OBJECTIVE: To examine the effect of HPV-16 E6 expression on the transcription of cellular genes, we used cDNA microarray in HPV-16 E6 transfected stable cancer cell lines. METHODS: Using cDNA microarray... -
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- The Effect of PLCgamma1 Pleckstrin Homology Domain on Il - 6 - induced B Cell Response
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Pyun KH, Choi IP, Han MY, Yoon SY, Song HK, Lee HY
- KMID: 1548377
- Korean J Immunol.
- 1997 Dec;19(4):525-532.
The pleckstrin homology (PH) domain is a protein module of approximately 100 amino acids, that has been found in signaling molecules, including serinelthreonine kinase, GTPase-activating protein, phospholipase, and some cytoskeletal... -
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