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G Protein Coupled Receptor Signaling: Recent Progress

Baik JH

  • KMID: 2199501
  • J Korean Soc Endocrinol.
  • 1999 Sep;14(3):440-452.
No abstract available.
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G Protein Oneogenes in Aeromegaly

Lee EJ, Lee HC

  • KMID: 2461506
  • J Korean Soc Endocrinol.
  • 1994 Sep;9(3):157-162.
No abstract available.
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Recent Progress in Understanding the Conformational Mechanism of Heterotrimeric G Protein Activation

Duc NM, Kim HR, Chung KY

Heterotrimeric G proteins are key intracellular coordinators that receive signals from cells through activation of cognate G protein-coupled receptors (GPCRs). The details of their atomic interactions and structural mechanisms have...
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Isolation of GTP binding from bovine brain

Kim JH

  • KMID: 2320404
  • Yeungnam Univ J Med.
  • 1993 Dec;10(2):360-368.
GTP binding protein (G-protein) associated with membrane and involved in signal transduction was isolated from bovine brain, and molecular weight of G protein was observed. As the results, cell membranes were...
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Action Mechanisms of Hormone Binding to Cell Surface Receptors: 1) G-protein Coupled Receptor Signalling as Targets for Hormone Action: (2) The Role and the Regulation of Phospolipase C

Park DJ

  • KMID: 2199639
  • J Korean Soc Endocrinol.
  • 2000 Jun;15(3):333-341.
No Abstract Available.
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Action Mechanisms of Hormone Binding to Cell Surface Receptors: 1) G-protein Coupled Receptor Signalling as Targets for Hormone Action: (1) Adenylate Cyclase Cascade

Baik JH

  • KMID: 2199638
  • J Korean Soc Endocrinol.
  • 2000 Jun;15(3):311-332.
No Abstract Available.
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Structural Aspects of GPCR-G Protein Coupling

Chung KY

  • KMID: 2317829
  • Toxicol Res.
  • 2013 Sep;29(3):149-155.
G protein-coupled receptors (GPCRs) are membrane receptors; approximately 40% of drugs on the market target GPCRs. A precise understanding of the activation mechanism of GPCRs would facilitate the development of...
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Role of pertussis toxin sensitive G-proteins on signal transduction of thyrotropin and insulin-like growth factor-I for the growth of thyrocytes

Cho BY, Lee DS, Yi KH, Shong MH, Lee HK, Koh CS, Min HK

  • KMID: 1697933
  • Korean J Intern Med.
  • 1991 Jul;41(1):94-102.
No abstract available.
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RGS Proteins and Opioid Signaling

Kim KS, Palmer PP, Kim KJ

The regulators of the G protein signaling (RGS) proteins are responsible for the rapid acceleration of the GTPase-activity intrinsic to the heterotrimeric G protein alpha subunits. As GTPase-activating proteins (GAP),...
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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers

Kwon S, Lim HJ

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it...
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A new member of alpha 1-adrenoceptor-coupled G alpha h (transglutaminase II) family in pig heart: purification and characterization

Yoo SM, Jeong HS, Han KJ, Cho SH, Lee HS, Yun HY, Kwon NS, Baek KJ

  • KMID: 754992
  • Exp Mol Med.
  • 1998 Jun;30(2):81-86.
We previously reported an identification of a 77-kDa GTP-binding protein that co-purified with the alpha 1-adrenoceptor following ternary complex formation. In the present paper, we report on the purification and characterization of...
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The proteins of synaptic vesicle membranes are affected during ageing of rat brain

Lee SR, Kim AR, Kim JS, Kim JB, Lee JY, Lee YL, Choe M, Park JB

  • KMID: 1457533
  • Exp Mol Med.
  • 2001 Dec;33(4):220-225.
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in...
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Effect of Ga2 gene mutation on the Expression of Thyrotropin-Releasing Hormone ( TRH ) Receptor Gene in GH3 Cells

Park SJ, Yang IM, Ryu JH, Chung JH, Jung JC, Ko KC, Kim YS, Choi YK

  • KMID: 1999281
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):357-363.
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Study of the Roles of Rab and Gh Proteins in Insulin-Induced GLUT4 Translocation Process

Hah JS, Go YH, Lee JH

Insulin stimulation of glucose transport in adipocytes results from the translocation of vesicles containing the GLUT4 glucose transporter from an intracellular pool to the plasma membrane. In mammalian cells a...
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Studies of G Protein Activation of Orphanin FQ in the Cerebrum, Thalamus and Spinal Cord of Monkeys

Lee H, Han JI

BACKGROUND: The aim of this in vitro study was to investigate [35S]GTP gamma S binding stimulated activation by orphanin FQ in monkey cerebral, thalamic, and spinal membranes. METHODS: A rhesus monkey...
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Phosphorylation of 46-kappa Da protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin

Kim AR, Choi WH, Lee SR, Kim JS, Jeon CY, Kim JI, Kim JB, Lee JY, Kim EG, Park JB

  • KMID: 1121097
  • Exp Mol Med.
  • 2002 Dec;34(6):434-443.
The release of neurotransmitter is regulated in the processes of membrane docking and membrane fusion between synaptic vesicles and presynaptic plasma membranes. Synaptic vesicles contain a diverse set of...
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Inhibition of Neurite Outgrowth by Stably Expressed Go alpha in F11 Cells

Ghil SH, Suh-Kim HY

  • KMID: 2030748
  • Korean J Anat.
  • 2002 Apr;35(2):125-131.
Heterotrimeric G proteins mediate signals generated by neurotransmitters and hormones. Among G proteins, Go is found in a large quantity in brain and growth cone membranes of neurons. In spite...
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System-Wide Expression and Function of Olfactory Receptors in Mammals

Oh SJ

Olfactory receptors (ORs) in mammals are generally considered to function as chemosensors in the olfactory organs of animals. They are membrane proteins that traverse the cytoplasmic membrane seven times and...
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G protein signaling in the parasite Entamoeba histolytica

Bosch DE, Siderovski DP

  • KMID: 2154234
  • Exp Mol Med.
  • 2013 Mar;45(3):e15.
The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among the known amebic factors contributing to pathogenesis are signaling pathways involving heterotrimeric and Ras superfamily G proteins. Here, we...
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Expression of signal transducing G proteins in human melanoma cell lines

Lee ES, Kang WH, Jin YH, Juhnn YS

  • KMID: 1532666
  • Exp Mol Med.
  • 1997 Dec;29(4):223-227.
Some malignant melanoma cells regress spontaneously by terminal differentiation, and understanding the mechanisms of this spontaneous regression can contribute to the development of a new therapy not only for melanoma...
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