- Recent Advances in Biosensors for Nucleic Acid and Exosome Detection
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Fu Z, Lu YC, Lai JJ
- KMID: 2447210
- Chonnam Med J.
- 2019 May;55(2):86-98.
- doi: 10.4068/cmj.2019.55.2.86
Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied... -
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- A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region
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Piao Y, Yun SY, Kim HS, Park BK, Ha HC, Fu Z, Jang JM, Back MJ, Shin IC, Won JH, Kim DK
- KMID: 2534702
- Biomol Ther.
- 2022 Nov;30(6):529-539.
- doi: 10.4062/biomolther.2022.071
Rheumatoid arthritis (RA) is a multifactorial immune-mediated disease, the pathogenesis of which involves different cell types. T-cell activation plays an important role in RA. Therefore, inhibiting T-cell activation is one... -
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- Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells
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Jang YJ, Won JH, Back MJ, Fu Z, Jang JM, Ha HC, Hong S, Chang M, Kim DK
- KMID: 2380288
- Biomol Ther.
- 2015 Sep;23(5):407-413.
- doi: 10.4062/biomolther.2015.075
Paraquat dichloride (N,N-dimethyl-4-4'-bipiridinium, PQ) is an extremely toxic chemical that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes multiple organ failure. In particular, PQ has... -
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- Effects of garlic intake on cancer: a systematic review of randomized clinical trials and cohort studies
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Lee J, Zhao N, Fu Z, Choi J, Lee HJ, Chung M
- KMID: 2522656
- Nutr Res Pract.
- 2021 Dec;15(6):773-788.
- doi: 10.4162/nrp.2021.15.6.773
BACKGROUND/OBJECTIVES: Due to the rapid increase of global cancer incidence and mortality and a high level of interest in cancer prevention, a systematic review of garlic intake and cancer risk... -
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- Development of a Label-Free LC-MS/MS-Based Glucosylceramide Synthase Assay and Its Application to Inhibitors Screening for Ceramide-Related Diseases
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Fu Z, Yun SY, Won JH, Back MJ, Jang JM, Ha HC, Lee HK, Shin IC, Kim JY, Kim HS, Kim DK
- KMID: 2442011
- Biomol Ther.
- 2019 Feb;27(2):193-200.
- doi: 10.4062/biomolther.2018.122
Ceramide metabolism is known to be an essential etiology for various diseases, such as atopic dermatitis and Gaucher disease. Glucosylceramide synthase (GCS) is a key enzyme for the synthesis of... -
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