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Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro

He MT, Lee AY, Park CH, Cho EJ

BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress...
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Evidence for beneficial effects of vitamin E

Niki E

Oxidative stress and lipid peroxidation have been implicated in the pathogenesis of various diseases, including atherosclerosis and fatty liver diseases, and consequently the role of antioxidants in the prevention and...
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Thyroid and Hydrogen Peroxide

Park DJ

The thyroid gland produces high concentrations of hydrogen peroxide (H2O2) which is used for the biosynthesis of the thyroid hormones, triiodothyronine and thyroxine. The most important step in thyroid hormone...
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Antioxidant Activity of Rubus coreanus Fruit Extract: In Comparison to Green Tea Extract

Yoon HJ, Kim CS, Lee KY, Yang SY

This study aimed to evaluate the antioxidant activity of Korean raspberry (Rubus coreanus Miq.) fruits, which are grown widely in the southwest area of Korea. Freeze-dried Rubus coreanus (RC) fruits...
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Moxifloxacin Ameliorates Oleic Acid-induced Acute Lung Injury by Modulation of Neutrophilic Oxidative Stress in Rats

Kim BY, Lee YM

BACKGROUND: Based on the known immunoregulatory functions of moxifloxacin on phagocytes, the therapeutic effect of moxifloxacin on oleic acid (OA)-induced acute lung injury (ALI) was investigated. METHODS: Moxifloxacin (10 mg/kg) was...
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Pretreatment of Diltiazem Ameliorates Endotoxin-Induced Acute Lung Injury by Suppression of Neutrophilic Oxidative Stress

Jang YS, Lee YM, Ahn WS, Lee SC, Kim KC, Hyun DS

BACKGROUND: Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory pulmonary edema of unknown pathogenesis. To investigate the pathogenesis of ARDS associated with neutrophilic oxidative stress, the role of...
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Effects of Oxygen Free Radical on Action Potential in Mouse Atrial Myocardium

Park HW, Jeong DH, Yoon NS, Koh JS, Lim SY, Lee SR, Hong SN, Kim KH, Sohn IS, Hong YJ, Kim JH, Kim W, Park RH, Ju JM, Ahn YK, Jeong MH, Cho JG, Kim JH, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: Reactive oxygen species are known to be produced when atrial fibrillation develops. This study was performed to investigate the effects of hydrogen peroxide (H2O2) on the action...
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Epilepsy and Oxygen Free Radicals

Kim WS

  • KMID: 2279034
  • Korean J Pediatr.
  • 2005 Sep;48(9):920-923.
Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, free radicals play an important role in seizure initiation and seizure-induced brain damage. Excessive production...
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Effects of Oxygen Free Radicals on KATP Channel Activity in Mouse Cardiac Myocytes

Park HW, Ju JM, Park OY, Park WS, Kim JH, Kim W, Ahn YK, Jeong MH, Park JC, Kim JH, Kang JC, Cho JG

BACKGROUND AND OBJECTIVE: Oxygen-derived free radicals (OFRs), produced as myocardium is reperfused after ischemic injury, contribute to reversible and irreversible cellular injury. KATP channels, activated by ischemia, have been reported...
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Effect of Melatonin on the Diabetes Mellitus Induced by Streptozotocin in Rats

Lee RR, Kim YH, Kwak CS, Yeo MY, Mun KC

  • KMID: 2008278
  • J Korean Diabetes Assoc.
  • 2002 Oct;26(5):357-365.
BACKGROUND: Oxygen free radicals are related to the pathogenesis and development of diabetes mellitus. The effect of melatonin, a known powerful antioxidant, was studied diabetes mellitus induced by streptozotocin in...
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Metabolism of Oxygen Free Radicals in the Regenerating Liver of Rats

Park SK, Park HY, Mun KC, Kim YH, Kwak CS

  • KMID: 1647121
  • Korean J Gastroenterol.
  • 2002 Oct;40(4):255-262.
BACKGROUND/AIMS: To know the metabolism of oxygen free radicals in the regenerating liver, the 70% (median and left lateral lobes) partial hepatectomy was performed in the Sprague-Dawley rats. METHODS: The original...
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Damage Induced by Oxygen Free Radicals in the Cell Fractionation of Regenerating Liver

Park HY, Mun KC

  • KMID: 2038324
  • Korean J Gastroenterol.
  • 2002 Apr;39(4):284-288.
BACKGROUND/AIMS: Oxygen free radicals can be defined as oxygen molecules or molecular fragments that have an unpaired electron. They are formed in all living organisms during physiological and pathophysiological metabolism,...
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Effect of Melatonin on Hemolysis Induced by Cyclosporine

Kwak CS, Mun KC, Suh SI

  • KMID: 1264081
  • Korean J Nephrol.
  • 2001 Sep;20(5):838-841.
Hemolysis is one of the side effects of cyclosporine(CsA). Some experimental and clinical data have strongly suggested that CsA-induced hemolysis is resulted from the increased production of free radical species...
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Development of semi-empirical model for radiochemical reactions

Lee RJ, Suh HS

A mathematical model, which represents the radio-chemical reactions in water, was developed to study the effect of the radio-chemical products on cell kiling. The five differential equations were solved using...
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The Effect of Taurine on Corneal Endothelial Damage by Free-radicals

Kwon OG, Kim KS

  • KMID: 2336996
  • J Korean Ophthalmol Soc.
  • 2001 May;42(5):736-744.
PURPOSE: To investigate the protective effect of taurine on the corneal endothelial damage by oxidative stress. METHODS: Rabbit corneas were mounted in the dual-chambered specular microscope and perfused with bicarbonate-Ringer...
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Protective Effect of Hyaluronic Acid on the Corneal Endothelial Function Against Free-Radical Damage

Kim KS, Woo KH, Kwon OG

  • KMID: 2205973
  • J Korean Ophthalmol Soc.
  • 2001 Mar;42(3):483-494.
PURPOSE: To investigate the protective effects of hyaluronic acid with glutathione and ascorbic acid on corneal endothelial function against free-radical damage. METHODS: bovine corneal endothelial(BCEN) cells were treated with a...
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Zinc-Induced Cell Death in H9c2 Cardiomyoblast cells

Park C, So HS, Choi HJ, Kim YH, Oh J, Choi MK, Chung YT, Park R

  • KMID: 2224525
  • Korean J Anat.
  • 2000 Dec;33(6):635-642.
Adriamycin (ADR) is a potent anticancer drug that causes often severe cardiomyopathy. Previous reports have demonstrated that zinc accumulation is shown in rat myocardial cells following ADR treatment. However, the...
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An Experimental Study on the Changes of Rabbit EEG by Reoxygenation after the Exposure to Carbon Monoxide

Son JI, Kim YY, Lee SJ, Nam JH, Song JC, Park HB

  • KMID: 2030708
  • Korean J Aerosp Environ Med.
  • 2000 Dec;10(4):336-346.
BACKGROUND: Hyperbaric oxygen (HBO) therapy is applied for the treatments of various diseases inducing hypoxic states. However, reoxygenation of previously hypoxic tissue results in significant tissue damages through the mechanisms...
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Fluorophotometric Detection of Oxygen Free Radicals in the Cornea and Lens after Excimer Laser Photore fractive Keratecto my in Rabbit

Heo JH, Wee WR, Lee JH

  • KMID: 2336930
  • J Korean Ophthalmol Soc.
  • 2000 Jul;41(7):1451-1457.
This study was performed to detect the oxidative stress in the cornea and lens in vivo by fluorophotometer after excimer laser photorefractive keratectomy(PRK). Twenty New Zealand white rabbits(20 eyes)were divided...
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The Study of the Change in the Oxidative System Balance in Preeclampsia

Kim SJ, Chung TY, Choi HY, Choi PS, Lee CH, Chung DY, Park DK

  • KMID: 2261974
  • Korean J Obstet Gynecol.
  • 2000 Jun;43(6):1008-1012.
OBJECTIVE: This study assesses the hypothesis that preeclampsia is associated with the change of oxidative system balance by measuring the lipid peroxidation and antioxidant activity in preeclampsia. METHOD: Venous blood samples...
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