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Prevalence of Drug Resistance-Associated Gene Mutations in Plasmodium vivax in Central China

Lu F, Wang B, Cao J, Sattabongkot J, Zhou H, Zhu G, Kim K, Gao Q, Han ET

  • KMID: 1792136
  • Korean J Parasitol.
  • 2012 Dec;50(4):379-384.
Resistance of Plasmodium spp. to anti-malarial drugs is the primary obstacle in the fight against malaria, and molecular markers for the drug resistance have been applied as an adjunct in...
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Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates

Baek EJ, Nam HW

The responses to antifolates of Toxoplasma gondii were investigated by measuring the dihydrofolate reductase (DHFR) activity, quantity of DHFR mRNA, and single-strand conformational polymorphism (SSCP) pattern. Pyrimethamine (PYM) and methotrexate...
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