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Effect of beta-Hydroxybutyrate on Flurothyl-Induced Seizure Susceptibility

Shin CG, Kim DW

  • KMID: 2176827
  • J Korean Child Neurol Soc.
  • 2010 Nov;18(2):225-229.
PURPOSE: The ketogenic diet (KD) remains a therapy in search of explanation although it is an established treatment for patients with intractable seizures. It was designed to mimic the biochemical...
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The Protective Effect of Chlorpromazine on Flurothyl-Induced Seizure

Kim DW

  • KMID: 2007390
  • J Korean Child Neurol Soc.
  • 2003 Nov;11(2):234-237.
PURPOSE: Chlorpromazine(CPZ) is known to inhibit glutamate ehydrogenase(GDH). Reductive amination of alpha-ketoglutarate is catalyzed by GDH and forms glutamate, a major excitatory neurotransmitter. Thus, I hypothesized that CPZ might have...
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Effect of the Ketogenic Diet on Flurothyl-Induced Seizure Susceptibility

Kim DW, Chae SA, Jung KY, Kim JM

  • KMID: 2333362
  • J Korean Epilepsy Soc.
  • 2001 Dec;5(2):119-123.
PURPOSE: Despite decades of clinical experience with the ketogenic diet (KD), its efficacy and mechanisms of action have been examined in few animal studies. The present study was designed to...
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