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Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans

Yoo JY, Kim SY, Hwang JA, Hong SH, Shin A, Choi IJ, Lee YS

Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types....
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Polymorphisms of 5, 10-Methylentetrahydrofolate Reductase (MTHFR C677T) and Methionine Synthase Reductase (MTRR A66G) as Maternal Risk Factors for Fetal Aneuploidy

Kim DJ, Kim SY, Park SY, Kim JW, Kim MY, Han JY, Yang JH, Ahn HK, Choi JS, Chung JH, Ryu HM

  • KMID: 2184456
  • J Genet Med.
  • 2008 Dec;5(2):119-124.
PURPOSE: Aneuploidy is the cause of diseases such as Down syndrome or Edward syndrome and, more generally, is a major cause of mental retardation and fetal loss. The purpose of...
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Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women

Kim DJ, Park BL, Koh JM, Kim GS, Kim LH, Cheong HS, Shin HD, Hong JM, Kim TH, Shin HI, Park EK, Kim SY

  • KMID: 1098086
  • Exp Mol Med.
  • 2006 Oct;38(5):519-524.
Homocysteine (Hcy) is thought to play an important role in the development of osteoporosis and fracture. Methionine synthase reductase (MTRR) is an enzyme involved in the conversion of Hcy to...
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