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Previously, we have reported that p-chlorophenylalanine (PCPA), a
serotonin depletor, profoundly increased pancreatic fluid and
bicarbonate secretion but remarkably inhibited pancreatic amylase
secretion in anesthetized rats. The present study was performed to
verify the...
In the present study, we investigated the effect of pretreatment of
p-chlorophenylalanine (PCPA), inhibitor of serotonin synthesis, on
lipopolysaccharide (LPS)-induced anorexia in rats. First of all,
effects of PCPA injection on food intake...
BACKGROUND: Hepatic steatosis is caused by metabolic stress associated with a positive lipid balance, such as insulin resistance and obesity. Previously we have shown the anti-obesity effects of inhibiting serotonin...