- MicroRNA-186 targets SKP2 to induce p27(Kip1)-mediated pituitary tumor cell cycle deregulation and modulate cell proliferation
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He Z, Chen L, Wang Q, Yin C, Hu J, Hu X, Fei F, Tang J
- KMID: 2443605
- Korean J Physiol Pharmacol.
- 2019 May;23(3):171-179.
- doi: 10.4196/kjpp.2019.23.3.171
Pituitary tumors are usually benign but can occasionally exhibit hormonal and proliferative behaviors. Dysregulation of the G1/S restriction point largely contributes to the over-proliferation of pituitary tumor cells. F-box protein... -
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