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Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats

Demedts I, Masaoka T, Kindt S, De Hertogh G, Geboes K, Farre R, Vanden Berghe P, Tack J

  • KMID: 2325788
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):161-170.
BACKGROUND/AIMS: Type 1 diabetes is often accompanied by gastrointestinal motility disturbances. Vagal neuropathy, hyperglycemia, and alterations in the myenteric plexus have been proposed as underlying mechanism. We therefore studied the...
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Validation of Octanoate Breath Test for Measuring Gastric Emptying in Rats

Demedts I, Vanormelingen C, Van Billoen H, Vanuytsel , Farre R, Masaoka T, Verbruggen A, Verbeke K, Vanden Berghe P, Tack J

  • KMID: 2325789
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):171-178.
BACKGROUND/AIMS: Lack of simple and repeatable tests hampers gastric emptying studies in rats. The aim of this study was to adapt the 14C-octanoate solid gastric emptying breath test for application...
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