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Series with complete resolution of left atrial appendage thrombi with apixaban in elderly patients

Lee SH, Han S

No abstract available.
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Guidance for Endoscopic Procedures in Patients Taking Novel Oral Anticoagulants

Kim KO

Anticoagulant agents are used to reduce the risk of thromboembolic complications in patients with atrial fibrillation or deep vein thrombosis. Several new generation of oral anticoagulants have been approved. These...
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Stroke Update 2011: New Antithrombotics

Seo KD, Lee KY

  • KMID: 2288709
  • Korean J Stroke.
  • 2012 Aug;14(2):62-66.
Several new antithrombotic drugs have been developed and approved to use in clinical practice recently. Dabigatran, a direct thrombin inhibitor, and rivaroxaban, a factor Xa inhibitor, have been approved in...
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New Oral Anticoagulants: General Features and Review of Pivotal Clinical Trials

Jang SW

For the last half century, vitamin K antagonists (VKAs) have been used for treatment and prevention of venous thromboembolism and stroke prevention in patients with atrial fibrillation. However, their fragile...
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Deep Vein Thrombosis and Neurovascular Injury after Total Hip Arthroplasty

Seo YS, Yim SJ

Deep vein thrombosis (DVT) is a relatively common complication of total hip arthroplasty. DVT can accompany symptoms of pain and swelling of the lower leg, and can lead to fatal...
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Epidural hematoma after total knee arthroplasty in a patient receiving rivaroxaban: A case report

Shin S, Kang H, Lee JW, Kim HG, Choi ES

Rivaroxaban, a factor Xa inhibitor, is one of the newly developed direct oral anticoagulants (DOAC). In recent times, it has been increasingly used in the prevention of pulmonary embolism in...
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Effect of Rivaroxaban on Fibrinolytic Therapy in Massive Pulmonary Embolism: Two Cases

Kim HJ, Koo SM, Ham NS, Kim KU, Uh ST, Kim YK

  • KMID: 2320494
  • Tuberc Respir Dis.
  • 2014 Mar;76(3):127-130.
The risk of dying from a pulmonary embolism (PE) is estimated to be about 30% if inotropic support is required and no cardiopulmonary arrest occurs. Fibrinolysis in massive PE is...
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Structure of heavy and light chains of blood coagulation factor VIII (FVIII) involved in the activation of FVIII

Oh SH, Kim HW, Kim YJ

  • KMID: 2045604
  • Exp Mol Med.
  • 1997 Jun;29(2):97-102.
Structure of human blood coagulation factor VIII (FVIII) in relation to its activation process was investigated. FVIII was purified from a commercial FVIII concentrate by immunoaffinity chromatography and its dissociated...
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Anaphylactoid Reactions after Thrombokinase Administration: Two cases

Kwon YE, Lee JH, Lee KN, Moon JI

The incidence of life-threatening anaphylactoid reactions during anesthesia has been increasing. Specific allergic reactions during anesthesia are usually due to muscle relaxants, barbiturates, local anesthetics, narcotics, radiocontrast media, antibiotics, and...
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Recent advances in the management of venous thromboembolism

Ageno W

Venous thromboembolism (VTE) is a spectrum of diseases that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Anticoagulant treatment is the mainstay of therapy for VTE. Unfractionated heparin (UFH)...
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Real-world Data and Recommended Dosage of Non-vitamin K Oral Anticoagulants for Korean Patients

Joung B

Regulatory approvals of non-vitamin K antagonist oral anticoagulants (NOACs) have been based on large randomized phase III trials evaluating dabigatran, rivaroxaban, apixaban, or edoxaban relative to warfarin for atrial fibrillation...
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Quantification of apixaban in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry

Jeong HC, Kim TE, Shin KH

Apixaban, an inhibitor of direct factor Xa, is used for the treatment of venous thromboembolic events or prevention of stroke. Unlike many other anticoagulant agents, it does not need periodic...
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Acute kidney injury aggravated by treatment initiation with apixaban: Another twist of anticoagulant-related nephropathy

Brodsky SV, Mhaskar NS, Thiruveedi S, Dhingra R, Reuben SC, Calomeni E, Ivanov I, Satoskar A, Hemminger , Nadasdy G, Hebert L, Rovin B, Nadasdy T

Anticoagulant-related nephropathy (ARN) was initially described in patients on warfarin (as warfarin-related nephropathy) and recently in those using dabigatran. Herein, we report clinical history and kidney biopsy findings in a...
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Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban

Yang H, Kim SR, Song MJ

Cirrhosis can occur with the development of portal vein thrombosis (PVT). PVT may aggravate portal hypertension, and it can lead to hepatic decompensation. The international guideline recommends for anticoagulation treatment...
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Antifactor Xa Levels in Critically Ill Korean Patients Receiving Enoxaparin for Thromboprophylaxis: A Prospective Observational Study

Lim SY, Jeon K, Kim HJ, Kim SM, Song J, Ha JM, Um SW, Koh WJ, Chung MP, Kim H, Kwon OJ, Suh GY

The aim of this study was to investigate antifactor Xa (aFXa) levels after once daily dose of 40 mg of enoxaparin and to evaluate factors influencing aFXa levels among Korean...
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Prophylaxis for Venous Thromboembolism Following Total Knee Arthroplasty: A Survey of Korean Knee Surgeons

Kim NK, Kim TK, Kim JM, Chun CH

PURPOSE: The purpose of this study is to provide information on the actual status and prevailing trend of prophylaxis for venous thromboembolism (VTE) following total knee arthroplasty (TKA) in South...
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Study of the Effect of Thromboplastin Preparation ( Thrombokinase ) on the Blood Coagulation

Lee YJ, Yoon DM, Cho CH, Park BM

Coagulants have been used for a long time to promote the hemostasis during operation. We have carried out the study to see the effect of the thromboplastin preparation. Thrombokinase, on...
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Rivaroxaban versus Low-Molecular-Weight Heparin for Venous Thromboembolism in Gastrointestinal and Pancreatobiliary Cancer

Lee JH, Oh YM, Lee SD, Lee JS

BACKGROUND: Low-molecular-weight heparin (LMWH) is the standard treatment for venous thromboembolism (VTE) in patients with active cancer. However, use of factor Xa inhibitors, such as rivaroxaban, is increasing on the...
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Antithrombotic Management of Patients with Nonvalvular Atrial Fibrillation and Ischemic Stroke or Transient Ischemic Attack: Executive Summary of the Korean Clinical Practice Guidelines for Stroke

Jung KH, Yu KH, Kim YD, Park JM, Hong KS, Rha JH, Kwon SU, Bae HJ, Heo JH, Lee BC, Yoon BW

Cardioembolic stroke related to nonvalvular atrial fibrillation is associated with a high recurrence rate and high mortality and morbidity. In this population, therefore, optimal anticoagulant therapy is required to prevent...
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Comparisons of Bleeding Risks between Rivaroxaban and Dalteparin for Treatment of Venous Thromboembolism in Cancer Patients

Kim YK, An SH, Kim JY, Chung JE, Gwak HS

BACKGROUND: Venous thromboembolism (VTE) is a common and life-threating condition in cancer patients. Low molecular weight heparins (LMWH), such as dalteparin, are recommended in the treatment of VTE. Also, rivaroxaban,...
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