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Single Versus Repetitive Traumatic Brain Injury: Current Knowledge on the Chronic Outcomes, Neuropathology and the Role of TDP-43 Proteinopathy

Janković T, Pilipović K

  • KMID: 2546570
  • Exp Neurobiol.
  • 2023 Aug;32(4):195-215.
  • doi: 10.5607/en23008
Traumatic brain injury (TBI) is one of the most important causes of death and disability in adults and thus an important public health problem. Following TBI, secondary pathophysiological processes develop over...
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Global Cerebral Ischemia-induced Depression Accompanies Alteration of Neuronal Excitability in the Infralimbic Cortex Layer 2/3 Pyramidal Neurons

Jang DC, Choi S, Chung G, Kim SK

  • KMID: 2546576
  • Exp Neurobiol.
  • 2023 Aug;32(4):302-312.
  • doi: 10.5607/en23017
Cerebral ischemia can lead to a range of sequelae, including depression. The pathogenesis of depression involves neuronal change of the medial prefrontal cortex (mPFC). However, how cerebral ischemia-induced changes manifest...
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Bias in Prestimulus Motor Cortical Activity Determines Decision-making Error in Rodents

Chae S, Sihn D, Kim SP

  • KMID: 2546574
  • Exp Neurobiol.
  • 2023 Aug;32(4):271-284.
  • doi: 10.5607/en23020
Decision-making is a complex process that involves the integration and interpretation of sensory information to guide actions. The rodent motor cortex, which is generally involved in motor planning and execution,...
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Advances in Amyloid-β Clearance in the Brain and Periphery: Implications for Neurodegenerative Diseases

Ullah R, Lee EJ

  • KMID: 2546571
  • Exp Neurobiol.
  • 2023 Aug;32(4):216-246.
  • doi: 10.5607/en23014
This review examines the role of impaired amyloid-β clearance in the accumulation of amyloid-β in the brain and the periphery, which is closely associated with Alzheimer's disease (AD) and cerebral...
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Gallic Acid Ameliorates Cognitive Impairment Caused by Sleep Deprivation through Antioxidant Effect

Pang X, Xu Y, Xie S, Zhang T, Cong L, Qi Y, Liu L, Li Q, Mo M, Wang G, Du X, Shen H, Li Y

  • KMID: 2546575
  • Exp Neurobiol.
  • 2023 Aug;32(4):285-301.
  • doi: 10.5607/en23015
Sleep deprivation (SD) has a profound impact on the central nervous system, resulting in an array of mood disorders, including depression and anxiety. Despite this, the dynamic alterations in neuronal...
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Presenilin 2 N141I Mutation Induces Hyperimmunity by Immune Cell-specific Suppression of REV-ERBα without Altering Central Circadian Rhythm

Nam H, Kim B, Lee Y, Choe HK, Yu SW

  • KMID: 2546573
  • Exp Neurobiol.
  • 2023 Aug;32(4):259-270.
  • doi: 10.5607/en23012
Circadian rhythm is a 24-hour cycle of behavioral and physiological changes. Disrupted sleep-wake patterns and circadian dysfunction are common in patients of Alzheimer Disease (AD) and are closely related with...
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NAG-1/GDF-15 Transgenic Female Mouse Shows Delayed Peak Period of the Second Phase Nociception in Formalin-induced Inflammatory Pain

Choi SR, Lee J, Moon JY, Baek SJ, Lee JH

  • KMID: 2546572
  • Exp Neurobiol.
  • 2023 Aug;32(4):247-258.
  • doi: 10.5607/en23019
Non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1), also known as growth differentiation factor-15 (GDF-15), is associated with cancer, diabetes, and inflammation, while there is limited understanding of the role of NAG-1 in...
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