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Diagnosis and Treatment of Eosinophilic Esophagitis

Kim SJ, Choi CW, Hwang CS

Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. The diagnostic criteria for EoE have changed with our growing knowledge over...
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Predictive Factors for Future Onset of Reflux Esophagitis: A Longitudinal Case-control Study Using Health Checkup Records

Toki Y, Yamauchi R, Kayashima E, Adachi K, Kishi K, Suetsugu H, Wada T, Endo H, Yamada H, Osaga S, Kamiya T, Nakada K, Iwakiri K, Haruma K, Joh T

  • KMID: 2523787
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):86-94.
  • doi: 10.5056/jnm20237
Background/Aims Although risk factors of reflux esophagitis (RE) have been investigated in numerous cross-sectional studies, little is known about predictive factors associated with future onset of RE. We investigated time courses...
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The Role of High Resolution Manometry in Non-Cardiac Chest Pain

Jang WY, Kim SW, Lee JW, Lee JY

The most common cause of noncardiogenic chest pain is gastroesophageal reflux disease, and other esophageal motility disorders are also frequent. Esophageal manometry is important for diagnosing esophageal motility disease. Recently,...
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Patients With Definite and Inconclusive Evidence of Reflux According to Lyon Consensus Display Similar Motility and Esophagogastric Junction Characteristics

Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP

  • KMID: 2521157
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):565-573.
  • doi: 10.5056/jnm20158
Background/Aims The role of esophageal high-resolution manometry (HRM) within Lyon consensus phenotypes, especially patients with inconclusive gastroesophageal reflux disease (GERD) evidence, has not been fully investigated. In this multicenter, observational study...
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Histopathological Analysis of Esophageal Mucosa in Patients with Achalasia

Lee BE, Kim GH, Shin N, Park DY, Song GA

Background/Aims: Achalasia is an esophageal motor disorder that leads to functional esophageal obstruction. Food stasis and bacterial fermentation can predispose an individual to esophageal mucosal inflammation, causing multifocal dysplasia and...
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Double Tract Reconstruction Reduces Reflux Esophagitis and Improves Quality of Life after Radical Proximal Gastrectomy for Patients with Upper Gastric or Esophagogastric Adenocarcinoma

Ji X, Jin C, Ji K, Zhang J, Wu X, Jia Z, Bu Z, Ji J

Purpose The aim of the present study was to compare the difference between double tract reconstruction and esophagogastrostomy. Materials and Methods Patients who underwent radical proximal gastrectomy with esophagogastrostomy or double...
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Effects of a mixture of Citri Pericarpium and Scutellariae Radix on acute reflux esophagitis in rats

Lee JA, Shin MR, Roh SS, Park HJ

Purpose: Reflux esophagitis is a disease caused by the reflux of stomach contents and stomach acid etc. into the esophagus due to defect in the lower esophageal sphincter and is...
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Reversibility of Endoscopic Features after Treatment for Eosinophilic Esophagitis

Yoon HJ, Youn YH, Park JC, Park H

Purpose: The prevalence and incidence of eosinophilic esophagitis (EoE) are increasing worldwide. Despite increased understanding of inflammatory pathogenesis, changes in endoscopic features after treatment of EoE have not been clearly...
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Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study

Kim SJ, Park MI, Kim GH, Lee MW, Jung K, Lee J, Seol SY, Jee SR, Lee HS, Jang JS, Cha JH, Busan, Ulsan, Gyeongnam Society of Neurogastroenterology and Motility

  • KMID: 2510064
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):71-77.
  • doi: 10.5056/jnm20069
Background/Aims The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking....
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Corrosive Esophagitis and Gastritis Induced by Glutaraldehyde Ingestion

Jun D, Kim HJ, Lee HS, Yoon HJ, Park JY, Kim BJ, Kim JG

Corrosive esophagitis and gastritis are characterized by caustic damage due to ingestion of chemical agents. Caustic agents cause tissue destruction through liquefaction or coagulation reactions. Here, we report a case...
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Esophageal Carcinosarcoma in a Patient with Corrosive Esophagitis

Kim YK, Shin O, Kim SS

Esophageal carcinosarcoma is a rare type of esophageal cancer characterized by both carcinomatous and sarcomatous components. Its endophytic growth tendency into the esophageal lumen leads to a higher curative resection...
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Eosinophilic Esophagitis with Angina Pectoris

Son MY, Kim SE, Park SJ, Park MI, Moon W, Kim JH, Jung K, Choi GS, Im SI

Eosinophilic esophagitis (EoE) is an immune or antigen-mediated chronic inflammatory esophageal disorder that is relatively rarein Asian countries. The main symptoms of EoE are dysphagia and food impaction. Although chest...
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Clinical Manifestations of Eosinophilic Esophagitis in Children and Adolescents: A Single-Center, Matched Case-Control Study

Roh JH, Ryoo E, Tchah H

Purpose: To examine the prevalence and clinical manifestations of eosinophilic esophagitis (EoE) in Korea children. Methods: The study was designed as a 1:2 matching case-control study. Using information from the endoscopic...
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Distal Esophageal Impedance Measured by High-resolution Esophageal Manometry With Impedance Suggests the Presence of Barrett’s Esophagus

Kataria R, Rosenfeld B, Malik Z, Harrison M, Smith MS, Schey R, Parkman HP

  • KMID: 2504002
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):344-351.
  • doi: 10.5056/jnm19105
Background/Aims Barrett’s esophagus (BE) is characterized by intestinal metaplasia in the distal esophagus. The aims of this study are to: (1) Compare baseline distal esophageal impedance (DEI) using high-resolution esophageal...
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The Lyon Consensus: Does It Differ From the Previous Ones?

Ghisa M, Barberio B, Savarino V, Marabotto E, Ribolsi M, Bodini G, Zingone F, Frazzoni M, Savarino E

  • KMID: 2503999
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):311-321.
  • doi: 10.5056/jnm20046
Gastroesophageal reflux disease (GERD) is a complex disorder with heterogeneous symptoms and a multifaceted pathogenetic basis, which prevent a simple diagnostic algorithm or any categorical classification. Clinical history, questionnaires and...
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Nationwide Multicenter Study of Eosinophilic Esophagitis in Korean Children

Lee K, Choe BH, Kang B, Kim S, Kim JY, Shim JO, Lee YM, Lee EH, Jang HJ, Ryoo E, Yang HR

Purpose: In East Asian countries, there are only a few epidemiologic studies of eosinophilic esophagitis (EoE) and no studies in children. We investigated the incidence and compared the clinical characteristics...
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Corrosive Esophageal Injury due to a Commercial Vinegar Beverage in an Adolescent

Chang J, Han SE, Paik SS, Kim YJ

Although gastroesophageal damage is commonly induced by accidental drinking of a strong acid or alkali, damage due to the consumption of a vinegar beverage is not well known. We report...
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Measurement of Esophageal Nocturnal Baseline Impedance: A Simplified Method

Hoshikawa , Sawada A, Sonmez S, Nikaki K, Woodland P, Yazaki E, Sifrim D

  • KMID: 2500681
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):.
  • doi: 10.5056/jnm19183
Background/Aims Mean nocturnal baseline impedance (MNBI) during multichannel intraluminal impedance pH-monitoring (MII-pH) reflects the status of esophageal mucosal integrity. MNBI is suggested as an adjunctive method to distinguish patients with...
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Exploring Esophageal Microbiomes in Esophageal Diseases: A Systematic Review

Park CH, Lee SK

  • KMID: 2500675
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):171-179.
  • doi: 10.5056/jnm19240
Studies that investigated esophageal microbiomes are limited when compared to those on intestinal microbiomes. Nevertheless, several studies have investigated the relationship between esophageal microbiomes and various esophageal diseases, owing to...
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Histologically confirmed upper gastrointestinal Crohn’s disease: is it rare or are we just not searching hard enough?

Saadah OI, Fallatah K, Baumann C, Elbaradie , Howladar F, Daiwali MT, Alshuaibi , Alsahafi M, Bokhary RY, Qari YA, Peyrin-Biroulet L, Mosli MH

Background/Aims: Crohn’s disease (CD) may involve the upper parts of the gastrointestinal (GI) tract including the esophagus, stomach, and duodenum. Clinical features of upper GI CD (UGICD) are not well...
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