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Characterizing affinity epitopes between prion protein and beta-amyloid using an epitope mapping immunoassay

Kang M, Kim SY, An SS, Ju YR

  • KMID: 2154253
  • Exp Mol Med.
  • 2013 Aug;45(8):e34.
Cellular prion protein, a membrane protein, is expressed in all mammals. Prion protein is also found in human blood as an anchorless protein, and this protein form is one of...
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Epitope Mapping of HIV1 gp41 Protein for Korean Anti - HIV1 Antisera using Synthetic Peptides

Hahm KS, Lee MK, Shin SY, Kim SY, Jang SY

  • KMID: 1547848
  • Korean J Immunol.
  • 1997 Mar;19(1):107-112.
The N-terminal sequence of HIV1 gp41 (amino acid residues 584-623) was known to be the immundominant region of HIV1 gp41 protein. In order to determine epitope for gp41 protein of...
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Characterization and epitope mapping of two monoclonal antibodies against human CD99

Gil MC, Lee MH, Seo JI, Choi YL, Kim MK, Jung KC, Park SH, Kim TJ

  • KMID: 1121094
  • Exp Mol Med.
  • 2002 Dec;34(6):411-418.
CD99 plays an critical role in the diapedesis of monocytes, T cell differentiation, and the transport of MHC molecules. Engagement of CD99 by agonistic monoclonal antibodies has been reported...
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Antigenic and immunogenic investigation of the virulence motif of the Newcastle disease virus fusion protein

Choi KS, Lee EK, Jeon WJ, Kwon JH

Newcastle disease (ND) caused by virulent Newcastle disease virus (NDV) is a highly contagious viral disease of poultry. Virulent NDVs characteristically have a multibasic amino acid sequence (virulence motif) such...
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An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding

Lee Y, Kim H, Chung J

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP...
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IgE Binding Reactivity of Peptide Fragments of Bla g 4, a Major German Cockroach Allergen

Shin KH, Jeong KY, Hong CS, Yong TS

Cockroaches have been recognized as a major cause of asthma. Bla g 4 is one of the most important German cockroach allergens. The aim of this study is to investigate...
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IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2

Lee MF, Chang CW, Song PP, Hwang GY, Lin SJ, Chen YH

PURPOSE: Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there...
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Transient phosphorylation of tumor associated microtubule associated protein (TMAP)/cytoskeleton associated protein 2 (CKAP2) at Thr-596 during early phases of mitosis

Hong KU, Choi YB, Lee JH, Kim HJ, Kwon HR, Seong YS, Kim HT, Park J, Bae CD, Hong KM

Tumor associated microtubule associated protein (TMAP), also known as cytoskeleton associated protein 2 (CKAP2) is a mitotic spindle-associated protein whose expression is cell cycle-regulated and also frequently deregulated in cancer...
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Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection

Chang KH, Kim MS, Hong GW, Shin YN, Kim SH

Epidermal growth factor receptor (EGFR) is an attractive target for tumor therapy because it is overexpressed in the majority of solid tumors and the increase in receptor expression levels has...
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beta PAK-interacting exchange factor may regulate actin cytoskeleton through interaction with actin

Lee CS, Kim KY, Im JB, Choi JW, Kim HK, Park JS, Shin EY, Kim SR, Kim EG

  • KMID: 1103327
  • Exp Mol Med.
  • 2004 Dec;36(6):582-587.
p21-activated kinase (PAK)-interacting exchange factor (PIX) is known to be involved in regulation of Cdc42/Rac GTPases and PAK activity. PIX binds to the proline-rich region of PAK, and regulates biological...
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