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Nitric oxide mediates epinephrine-induced apoptotic cell death of trabecular meshwork cells in vitro

Kim JW, Kim SK, Kim KH

To evaluate the effect of epinephrine on the cellular proliferation and production of nitric oxide (NO) in trabecular meshwork (TM) cells, cultured porcine TM cells were exposed to epinephrine at...
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Effect of Dexamethasone and Epinephrine on Metallothionein Level in the Perfused Rat Liver

Lee HS, Oh SH

The effect of dexamethasone (10(-5)M) and epinephrine (10(-6)M) on the biosynthesis of metallothionein (MT) in the perfused rat liver was investigated. MT synthesis was determined by measuring the incorporation of...
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Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways

Shah BH, Siddiqui A, Qureshi KA, Khan M, Rafi S, Ujan VA, Yakoob MY, Rasheed H, Saeed SA

  • KMID: 755026
  • Exp Mol Med.
  • 1999 Mar;31(1):42-46.
Our previous studies have shown that subthreshold concentrations of two platelet agonists exert synergistic effects on platelet aggregation. Here we studied the mechanism of synergistic interaction of 5-hydroxytryptamine (5-HT) and epinephrine mediated platelet...
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Histopathological changes in the extraocular muscles after retrobulbar anesthesia

I GU, Chang BL

Local anesthetics commonly used in ophthalmic surgery (0.5 to bupivacainehydrochloride,2.O% lidocaine hydrochloride,0.38% bupivacaine-1.O% lidocaine-l:1OO,000 epinephrine mixture) were injected into the retrobulbar space of rabbits. Physiologic saline was injected into that...
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Regulation of leptin gene expression by insulin and growth hormone in mouse adipocytes

Lee KN, Jeong IC, Lee SJ, Oh SH, Cho MY

  • KMID: 1457535
  • Exp Mol Med.
  • 2001 Dec;33(4):234-239.
The role of leptin in the control of obesity, insulin resistance and type II diabetes has been reported, however, the regulatory mechanism of leptin in animals affected by hormones is...
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