- Exploratory Study of Epidermis, Basement Membrane Zone, Upper Dermis Alterations and Wnt Pathway Activation in Melasma Compared to Adjacent and Retroauricular Skin
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Espósito , Brianezi G, de Souza N, Miot LD, Miot HA
- KMID: 2471335
- Ann Dermatol.
- 2020 Apr;32(2):101-108.
- doi: 10.5021/ad.2020.32.2.101
BACKGROUND: Melasma is a chronic acquired focal hypermelanosis which pathogenesis has not been fully elucidated. Classical pathophysiologic studies have analysed the affected and perilesional areas, but little is known about... -
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- Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model
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Kim M, Jeong H, Lee B, Cho Y, Yoon WK, Cho A, Kwon G, Nam KT, Ha H, Lim KM
- KMID: 2456220
- Biomol Ther.
- 2019 Sep;27(5):457-465.
- doi: 10.4062/biomolther.2018.214
Patients with diabetes mellitus (DM) often suffer from diverse skin disorders, which might be attributable to skin barrier dysfunction. To explore the role of lipid alterations in the epidermis in... -
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- Adiponectin Attenuates the Inflammation in Atopic Dermatitis-Like Reconstructed Human Epidermis
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Seo HS, Seong KH, Kim CD, Seo SJ, Park BC, Kim MH, Hong SP
- KMID: 2439064
- Ann Dermatol.
- 2019 Apr;31(2):186-195.
- doi: 10.5021/ad.2019.31.2.186
BACKGROUND: Atopic dermatitis (AD) is a chronic disorder, with a vicious cycle of repetitive inflammation and deterioration of the epidermal barrier function. Adiponectin, an adipokine, has anti-inflammatory effects on various... -
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- Dietary effect of green tea extract on hydration improvement and metabolism of free amino acid generation in epidermis of UV-irradiated hairless mice
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Choi S, Shin J, Lee B, Cho Y
- KMID: 2357129
- J Nutr Health.
- 2016 Oct;49(5):269-276.
- doi: 10.4163/jnh.2016.49.5.269
PURPOSE: Ultraviolet (UV) irradiation decreases epidermal hydration, which is maintained by reduction of natural moisturizing factors (NMFs). Among various NMFs, free amino acids (AA) are major constituents generated by filaggrin... -
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- CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin
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Choi G, Roh J, Park CS
- KMID: 2353598
- J Pathol Transl Med.
- 2016 Sep;50(5):361-368.
- doi: 10.4132/jptm.2016.06.19
BACKGROUND: CD99 is a cell surface transmembrane glycoprotein expressed in various tissues. CD99 is differentially expressed between subpopulations of each tissue and is highly expressed in certain hematopoietic and precursor... -
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- Characterization of mesenchymal cells beneath cornification of the fetal epithelium and epidermis at the face: an immunohistochemical study using human fetal specimens
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Kim JH, Jin ZW, Murakami G, Cho BH
- KMID: 2308931
- Anat Cell Biol.
- 2016 Mar;49(1):50-60.
- doi: 10.5115/acb.2016.49.1.50
Fetal development of the face involves a specific type of cornification in which keratinocytes provide a mass or plug to fill a cavity. The epithelial-mesenchymal interaction was likely to be... -
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- Comparative effect of dietary borage oil and safflower oil on anti-proliferation and ceramide metabolism in the epidermis of essential fatty acid deficient guinea pigs
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Lee SR, Cho Y
- KMID: 2209898
- J Nutr Health.
- 2015 Aug;48(4):319-326.
- doi: 10.4163/jnh.2015.48.4.319
PURPOSE: Borage oil (BO) and safflower oil (SO) are efficacious in reversing epidermal hyperproliferation, which is caused by the disruption of epidermal barrier. In this study, we compared the antiproliferative... -
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- Protease-Activated Receptor-2 Is Associated with Terminal Differentiation of Epidermis and Eccrine Sweat Glands
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Shin YS, Kim HW, Kim CD, Kim HW, Park JW, Jung S, Lee JH, Ko YK, Lee YH
- KMID: 2171490
- Ann Dermatol.
- 2015 Aug;27(4):364-370.
- doi: 10.5021/ad.2015.27.4.364
BACKGROUND: Protease-activated receptor 2 (PAR-2) participates in various biological activities, including the regulation of epidermal barrier homeostasis, inflammation, pain perception, and melanosome transfer in the skin. OBJECTIVE: To evaluate the basic... -
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- Expression of Antimicrobial Peptides and Proteins in Epidermis Equivalents Exposed to Salt Water and Narrowband Ultraviolet B Radiation
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Gambichler T, Terras S, Skrygan M
- KMID: 2265520
- Ann Dermatol.
- 2014 Oct;26(5):666-668.
- doi: 10.5021/ad.2014.26.5.666
No abstract available. -
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- Ultrastructural immunolocalization of beta-defensin-27 in granulocytes of the dermis and wound epidermis of lizard suggests they contribute to the anti-microbial skin barrier
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Alibardi L
- KMID: 2046765
- Anat Cell Biol.
- 2013 Dec;46(4):246-253.
- doi: 10.5115/acb.2013.46.4.246
The high resistance to infections in lizard wounds suggests that these reptiles possess effective antimicrobial peptides in their tissues. The present immunocytochemical study shows the cellular localization of beta-defensin 27... -
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- Reduced Expression of Cyclins and Proliferative Indices on the Psoriatic Epidermis after 12 Weeks of Oral Cyclosporin Therapy
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Han SS, Hyun OS, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK
- KMID: 1881992
- Ann Dermatol.
- 2006 Oct;18(2):51-58.
- doi: 10.5021/ad.2006.18.2.51
Cell growth characterized by cell cycle progression is regulated by cyclin-dependent kinase (CDK). CDKs are activated by binding cyclins such as cyclin A, cyclin B, cyclin D1, and cyclin E.... -
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- The Immunohistochemical Study of MAPKs Expression in Psoriatic Epidermis
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Kim SH, Ko JH, Choi KC, Chung BS
- KMID: 2158525
- Ann Dermatol.
- 2004 Sep;16(3):99-104.
- doi: 10.5021/ad.2004.16.3.99
No abstract available. -
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- Numerical Changes of Melanocytes in Artificial Epidermis Reconstructed by Keratinocytes and Melanocytes Coculture
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Song IH
- KMID: 2030763
- Korean J Anat.
- 2004 Apr;37(2):199-207.
To follow up the change of melanocytes to keratinocytes ratio in stratified epidermis reconstructed by mixed culture of these cells, the author investigated the ratio of melanocyte to keratinocyte in... -
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- The Expression of the alpha-Melanocyte Stimulating Hormone (alpha-MSH) and Melanocortin-1 Receptor (MC1R) in the Epidermis of the Vitiligo
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Cha YC, Lee HJ, Lee SJ, Na GY, Chung SL
- KMID: 2302963
- Korean J Dermatol.
- 2003 Jun;41(6):690-695.
BACKGROUND: Vitiligo is a skin disease that is characterized by the loss of cutaneous pigmentation. alpha-Melanocyte stimulating hormone (alpha-MSH) is a neuroimmunomodulating peptide derived from proopiomelanocortin, and melanocortin-1 receptor (MC1R)... -
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- Immunohistochemical Study of TGF- type I and type II receptor Expression in Psoriatic Epidermis
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Lee J, Kim YK, Koo SW, Choi GS
- KMID: 2230357
- Korean J Dermatol.
- 2000 Sep;38(9):1205-1211.
BACKGROUND: Previous studies have demonstrated the pathogenetic role and expression of TGF-beta in psoriatic lesion. Transforming growth factor s are a family of growth factors with inhibitory effects on epithelial... -
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- Expression of Elafin in the Epidermis of Cutaneous Fungal Infection
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Kim CH, Song HJ
- KMID: 2248557
- Korean J Infect Dis.
- 2000 Feb;32(1):21-26.
BACKGROUND: Elafin is a serine proteinase inhibitor first discovered in keratinocytes from hyperproliferative human epidermis. In addition to the proteinase inhibiting domain, elafin contains multiple transglutaminase substrate domains which enable... -
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- Presence of Progesterone Receptors in the Granular Cell Layer of Epidermis: Immunohistochemical Localization of Estrogen and Progesterone Receptors
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Suh JC, Seo SK, Na GY
- KMID: 2383026
- Ann Dermatol.
- 1999 Oct;11(4):214-217.
- doi: 10.5021/ad.1999.11.4.214
BACKGROUND: Hormones influence various normal biological processes in the skin and hairs. OBJECTIVE: This study was undertaken to investigate the presence of estrogen receptors(ER) and progesterone receptors (PR) in the skin... -
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- Expression of p53, pRb, p16, p21 and PCNA on Psoriatic Epidermis
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Chang SE, Sung KJ, Moon KC, Koh JK, Choi JH
- KMID: 2232153
- Korean J Dermatol.
- 1999 Sep;37(9):1286-1295.
BACKGROUND: Psoriasis is a chronic disorder which is characterized by hyperproliferation and abnormal differentiation of keratinocytes with T-cell infiltration. There is increasing evidence that inactivation of tumor-suppressor genes can promote... -
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- Expression Patterns of Cytokeratin and Involucrin in the Epidermis of the Artificial Skin Reconstructed by Cultured Cells
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Song IH, Lee CK, Sung EK
- KMID: 2071845
- Korean J Phys Anthropol.
- 1999 Jun;12(1):83-90.
To investigate differentiation and growth process of keratinocytes in organotypic cultured skin, we carried out immunohistochemical studies for cytokeratin (CK) 10, 14, 16, 17 and involucrin in the cultured skin.... -
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- Suction Auto Epidermal Graft on Removal of Epidermis of Depigmented Lesion with Radio-frequency Irradiation
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Park JK, Kim HJ, No HS, Kim TW, Lee JH
- KMID: 2303396
- Korean J Dermatol.
- 1999 Apr;37(4):481-487.
BACKGROUND: Suction auto epidermal graft for the treatment of stable vitiligo has become popular clinically. In general, depigmented epidermis is removed by liquid nitrogen freezing for preparation of the recipient... -
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