- Discordance of Epidermal Growth Factor Receptor Mutation between Brain Metastasis and Primary Non-Small Cell Lung Cancer
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Kim KM, Lee SH, Kim SM, Kim NY, Gwak HS, Shin SH, Kwon JW, Yoo H
- KMID: 2461187
- Brain Tumor Res Treat.
- 2019 Oct;7(2):137-140.
- doi: 10.14791/btrt.2019.7.e44
BACKGROUND: The aim of this study was to compare epidermal growth factor receptor (EGFR) mutations between non-small cell lung cancer (NSCLC) and corresponding brain metastases (BMs) in Korea society. METHODS: From... -
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- Human Epidermal Growth Factor Receptor 2-Subtype Invasive Ductal Carcinoma Recurring as Basal-Human Epidermal Growth Factor Receptor 2-Subtype Squamous Cell Carcinoma
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An J, Yoo Y, Kim HG, Woo J, Lee KE, Kwon H, Lim W, Sung SH, Paik NS, Moon BI
- KMID: 2458868
- J Breast Cancer.
- 2019 Sep;22(3):484-490.
- doi: 10.4048/jbc.2019.22.e31
Squamous cell carcinoma of the breast and its subtype, basal-human epidermal growth factor receptor 2 (HER2) phenotype, are very rare. Herein, we report a patient who developed recurrence of squamous... -
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- Comparison of cobas EGFR Mutation Test v2 and PANAMutyper-R-EGFR for Detection and Semi-Quantification of Epidermal Growth Factor Receptor Mutations in Plasma and Pleural Effusion Supernatant
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Han AL, Kim HR, Choi KH, Hwang KE, Zhu M, Huang Y, Wu M, Lee YJ, Park MC, Cho JH, Park DS
- KMID: 2450971
- Ann Lab Med.
- 2019 Sep;39(5):478-487.
- doi: 10.3343/alm.2019.39.5.478
BACKGROUND: Plasma epidermal growth factor receptor (EGFR) mutation tests are less invasive than tissue EGFR mutation tests. We determined which of two kits is more efficient: cobas EGFR Mutation test... -
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- The relation between serum levels of epidermal growth factor and necrotizing enterocolitis in preterm neonates
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Ahmed HM, Kamel NM
- KMID: 2456191
- Korean J Pediatr.
- 2019 Aug;62(8):307-311.
- doi: 10.3345/kjp.2018.07108
PURPOSE: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a... -
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- Association between EGF and EGFR Gene Polymorphisms and Susceptibility to Alopecia Areata in the Korean Population
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Won YY, Haw S, Chung JH, Lew BL, Sim WY
- KMID: 2451497
- Ann Dermatol.
- 2019 Aug;31(4):489-492.
- doi: 10.5021/ad.2019.31.4.489
No abstract available. -
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- A Nomogram for Predicting the Oncotype DX Recurrence Score in Women with T1-3N0-1miM0 Hormone Receptor‒Positive, Human Epidermal Growth Factor 2 (HER2)‒Negative Breast Cancer
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Lee SB, Kim J, Sohn G, Kim J, Chung IY, Kim HJ, Ko BS, Son BH, Ahn SH, Lee JW, Jung KH
- KMID: 2454299
- Cancer Res Treat.
- 2019 Jul;51(3):1073-1085.
- doi: 10.4143/crt.2018.357
PURPOSE: This preliminary study was conducted to evaluate the association between Oncotype DX (ODX) recurrence score and traditional prognostic factors. We also developed a nomogram to predict subgroups with low... -
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- Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy
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Jang Y, Cho EY, Cho SY
- KMID: 2450126
- J Breast Cancer.
- 2019 Jun;22(2):336-340.
- doi: 10.4048/jbc.2019.22.e17
Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone... -
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- Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin
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An JH, Lee HJ, Yoon MS, Kim DH
- KMID: 2444857
- Ann Dermatol.
- 2019 Jun;31(3):263-271.
- doi: 10.5021/ad.2019.31.3.263
BACKGROUND: Hyaluronic acid (HA)-based microneedle patch has recently been studied for wrinkle improvement. Cross-linked HA (CLHA) is widely used in dermal fillers. Acetyl hexapeptide-8 (AHP-8) and epidermal growth factor (EGF)... -
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- A Randomized, Open-Label, Phase II Study Comparing Pemetrexed Plus Cisplatin Followed by Maintenance Pemetrexed versus Pemetrexed Alone in Patients with Epidermal Growth Factor Receptor (EGFR)-Mutant Non-small Cell Lung Cancer after Failure of First-Line EGFR Tyrosine Kinase Inhibitor: KCSG-LU12-13
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Yoo KH, Lee SJ, Cho J, Lee KH, Park KU, Kim KH, Cho EK, Choi YH, Kim HR, Kim HG, Ahn HJ, Lee HY, Yun HJ, Kang JH, Jeong J, Choi MY, Jung SH, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ
- KMID: 2464417
- Cancer Res Treat.
- 2019 Apr;51(2):718-726.
- doi: 10.4143/crt.2018.324
PURPOSE: The optimal cytotoxic regimens have not been established for patients with non-small cell lung cancer (NSCLC) who develop disease progression on first-line epidermal growth factor receptor tyrosine kinase inhibitor... -
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- Topical Administration of the Recombinant Human Epidermal Growth Factor (EGF) Containing Ointment on the Tendon Exposed Skin Defect in Foot Digit: A Case Report
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Jeon M, Kim SY
- KMID: 2435192
- J Korean Burn Soc.
- 2018 Dec;21(2):59-62.
- doi: 10.0000/jkbs.2018.21.2.59
Contact burn is usually caused by prolonged contact to hot material and results in deep dermal injury. As a result, skin and soft tissue defects occur, and coverage of defect... -
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- Clinical Implications According to Diagnostic Methods of Human Epidermal Growth Factor Receptor 2 Positivity in Breast Cancer: A Retrospective Study
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Kim BK, Jeong J, Han W, Yoon TI, Seong MK, Jung JH, Jung SH, Lee J, Sun WY, Korean Breast Cancer Society
- KMID: 2434906
- J Breast Dis.
- 2018 Dec;6(2):60-72.
- doi: 10.14449/jbd.2018.6.2.60
PURPOSE: According to American Society of Clinical Oncology/College of American Pathologists guidelines, breast cancer is human epidermal growth factor receptor 2 (HER2) positive if there is HER2 protein overexpression at... -
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- PIK3CA Mutations and Neoadjuvant Therapy Outcome in Patients with Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: A Sequential Analysis
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Seo Y, Park YH, Ahn JS, Im YH, Nam SJ, Cho SY, Cho EY
- KMID: 2429816
- J Breast Cancer.
- 2018 Dec;21(4):382-390.
- doi: 10.4048/jbc.2018.21.e48
PURPOSE: PIK3CA mutation is considered to be a possible cause for resistance to neoadjuvant chemotherapy (NAC) in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. We investigated the association... -
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- Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer
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Yun S, Kwak Y, Nam SK, Seo AN, Oh HK, Kim DW, Kang SB, Lee HS
- KMID: 2424807
- Cancer Res Treat.
- 2018 Oct;50(4):1351-1361.
- doi: 10.4143/crt.2017.487
PURPOSE: Molecular treatments targeting epidermal growth factor receptors (EGFRs) are important strategies for advanced colorectal cancer (CRC). However, clinicopathologic implications of EGFRs and EGFR ligand signaling have not been fully... -
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- The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma
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Huang YH, Hsu KH, Tseng JS, Chen KC, Hsu CH, Su KY, Chen JJ, Chen HW, Yu SL, Yang TY, Chang GC
- KMID: 2424801
- Cancer Res Treat.
- 2018 Oct;50(4):1294-1303.
- doi: 10.4143/crt.2017.512
PURPOSE: The main objective of this study was to investigate the relationship among the clinical characteristics and the frequency of T790M mutation in advanced epidermal growth factor receptor (EGFR)–mutant lung... -
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- Serum Soluble Epidermal Growth Factor Receptor Level Increase in Patients Newly Diagnosed with Type 2 Diabetes Mellitus
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Kim JM, Choung S, Joung KH, Lee JH, Kim HJ, Ku BJ
- KMID: 2418723
- Diabetes Metab J.
- 2018 Aug;42(4):343-347.
- doi: 10.4093/dmj.2017.0082
We analyzed circulating soluble epidermal growth factor receptor (sEGFR) levels in humans. Serum sEGFR levels were higher in subjects with newly diagnosed type 2 diabetes mellitus compared with controls. Serum... -
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- Necessity of In Situ Hybridization Test of Human Epidermal Growth Factor Receptor 2 (HER2) Status in Breast Cancer Patients with Equivocal HER2 Immunohistochemistry Results
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Paik HJ, Choi HJ, Ryu JM, Park S, Kim I, Lee SK, Yu J, Kim SW, Nam SJ, Lee JE
- KMID: 2434909
- J Breast Dis.
- 2018 Jun;6(1):1-10.
- doi: 10.14449/jbd.2018.6.1.1
PURPOSE: Accurate human epidermal growth factor receptor 2 (HER2) status is important in predicting prognosis and providing treatment for HER2-positive breast cancer patients. However, performing in situ hybridization (ISH) can... -
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- Epidermal Growth Factor Attenuated the Expression of Inflammatory Cytokines in Human Epidermal Keratinocyte Exposed to Propionibacterium acnes
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Kim JM, Choo JE, Lee HJ, Kim KN, Chang SE
- KMID: 2399755
- Ann Dermatol.
- 2018 Feb;30(1):54-63.
- doi: 10.5021/ad.2018.30.1.54
BACKGROUND: While the beneficial effects of topical epidermal growth factor (EGF) on wound healing have been repeatedly reported, there are few reports about the effects of EGF on inflammatory skin... -
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- Epidermal growth factor receptor mutation and pattern of brain metastasis in patients with non-small cell lung cancer
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Baek MY, Ahn HK, Park KR, Park HS, Kang SM, Park I, Kim YS, Hong J, Sym SJ, Park J, Lee JH, Shin DB, Cho EK
- KMID: 2411521
- Korean J Intern Med.
- 2018 Jan;33(1):168-175.
- doi: 10.3904/kjim.2015.158
BACKGROUND/AIMS: We investigated the time taken for patients with metastatic non-small cell lung cancer (NSCLC) to develop brain metastases (BM), as well as their subsequent overall median survival following diagnosis,... -
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- Prognostic Value of Estrogen and Progesterone Receptor Expression in Low Proliferative Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer
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Lee Y, Park I, Cho H, Yang K, Kim J, Park K, Gwak G
- KMID: 2401817
- J Breast Dis.
- 2017 Dec;5(2):64-70.
- doi: 10.14449/jbd.2017.5.2.64
PURPOSE: Approximately two-thirds of breast cancer are estrogen-dependent cancers, which express estrogen receptor (ER)/progesterone receptor (PR). We investigated the prognostic value of ER/PR expression in human epidermal growth factor receptor 2... -
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- Phosphorylated S6 Kinase-1 as Predictive Marker of Lapatinib Efficacy in Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer Patients
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Ko EB, Seong MK, Choi HS, Park CS, Choi JH, Lee JK, Seol H, Kim HA, Noh WC
- KMID: 2401816
- J Breast Dis.
- 2017 Dec;5(2):57-63.
- doi: 10.14449/jbd.2017.5.2.57
PURPOSE: The 40S ribosomal protein S6 kinase-1 (S6K1) is a crucial downstream effector of the PI3K/AKT/mTOR pathway. S6K1 overexpression is found in 10% to 30% of breast cancers and is... -
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