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27-Hydroxycholesterol induces macrophage gene expression via LXR-dependent and -independent mechanisms

Kim BY, Son Y, Cho Hr, Lee D, Eo SK, Kim K

27-Hydroxycholesterol (27OHChol) exhibits agonistic activity for liver X receptors (LXRs). To determine roles of the LXR agonistic activity in macrophage gene expression, we investigated the effects of LXR inhibition on...
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Subungual Ganglion Cyst Mimicking Glomus Tumor

Doh GH, Kim BS, Shin H, Ahn KC, Hong KY, Han YS, Eo S

Subungual masses accompanying nail deformity are of common occurrence and uniquely confirmed by histopathologic examination postoperatively. Although glomus tumor is most frequently diagnosed with its specific clinical triad, other rarer...
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Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling Severe fever with thrombocytopenia and type I interferon

Park SC, Park JY, Choi JY, Lee SG, Eo SK, Oem JK, Tark DS, You M, Yu DH, Chae JS, Kim B

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS...
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The Interplay between Host Immunity and Respiratory Viral Infection in Asthma Exacerbation

Hossain FM, Choi JY, Uyangaa E, Park SO, Eo SK

Asthma is one of the most common and chronic diseases characterized by multidimensional immune responses along with poor prognosis and severity. The heterogeneous nature of asthma may be attributed to...
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Revisiting the Posterior Interosseous Artery Flap

Eo SR, Hwang SH, Hong KY, Lim SA, Lee GJ

The posterior interosseous artery (PIA) flap is one of the options for hand and upper extremity reconstruction. It does not sacrifice the main arteries of the hand, the radial and...
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A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response

Won G, Eo SK, Park SY, Hur J, Lee JH

Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive...
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Delayed formation of sterile abscess after zygomaticomaxillary complex fracture treatment with bioabsorbable plates

Doh G, Bahk S, Hong KY, Lim S, Han KM, Eo S

We present a patient who showed a sterile abscess after facial bone fixation with bioabsorbable plates and screws. He had zygomaticomaxillary complex and periorbital fracture due to falling down. The...
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Early Coverage with Advancement Flap in Laser Induced Dermal Injury on Neck: A Case Report

Doh G, Hwang S, Bahk S, Hong KY, Eo S, Lim S

Burn injury is one of the most common complications associated with laser procedure. A 38-year-old woman underwent laser procedure for skin rejuvenation on her neck at a local aesthetic clinic....
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Huge Abscess due to Mycobacterium Abscessus Infection after Breast Augmentation

Hwang S, Bahk S, Chung JW, Hong KY, Lim S, Eo S

Periprosthetic capsular contracture, implant rupture, and deflation are well-known delayed complications of augmentation mammaplasty. However, infection remains the most common cause of reoperation after breast implant surgery. We report the...
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Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties

Kim EJ, Seo SG, Shin HS, Lee DJ, Kim JH, Lee DY

BACKGROUND: The pericytes in the blood vessel wall have recently been identified to be important in regulating vascular formation, stabilization, remodeling, and function. We isolated and identified pericyte-like platelet-derived growth...
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Exacerbation of Japanese Encephalitis by CD11c(hi) Dendritic Cell Ablation Is Associated with an Imbalance in Regulatory Foxp3⁺ and IL-17⁺CD4⁺ Th17 Cells and in Ly-6C(hi) and Ly-6C(lo) Monocytes

Choi JY, Kim JH, Patil AM, Kim SB, Uyangaa E, Hossain FM, Eo SK

Japanese encephalitis (JE) is neuroinflammation characterized by uncontrolled infiltration of peripheral leukocytes into the central nervous system (CNS). We previously demonstrated exacerbation of JE following CD11c(hi) dendritic cell (DC) ablation...
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Vascular Augmentation in Renal Transplantation: Supercharging and Turbocharging

Jeong EC, Hwang SH, Eo SR

The most common anatomic variant seen in donor kidneys for renal transplantation is the presence of multiple renal arteries, which can cause an increased risk of complications. Accessory renal arteries...
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PI3K and ERK signaling pathways are involved in differentiation of monocytic cells induced by 27-hydroxycholesterol

Son Y, Kim BY, Park YC, Eo SK, Cho HR, Kim K

27-Hydroxycholesterol induces differentiation of monocytic cells into mature dendritic cells, mDCs. In the current study we sought to determine roles of the PI3K and the ERK pathways in the 27OHChol-induced...
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Atypical Presentation of Subungal Melanoma

Hwang SH, Bahk S, Eo S

Malignant melanomas sometimes present with nail or periungual pigmentation, as a subungual melanoma. This pigmentation also occurs in nonmelanoma skin disorders. Therefore, biopsy is mandatory for the absolute diagnosis. We...
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Wrist Pain due to Abnormal Extensor Carpi Ulnaris Tendon

Eo S, Bahk S, Jones NF

No abstract available.
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Close-by Islanded Posterior Tibial Artery Perforator Flap: For Coverage of the Ankle Defect

Bahk S, Hwang S, Kwon C, Jeong EC, Eo SR

PURPOSE: Soft tissue coverage of the distal leg and ankle region represents a surgical challenge. Beside various local and free flaps, the perforator flap has recently been replaced as a...
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Demineralized Bone Matrix Injection in Consolidation Phase Enhances Bone Regeneration in Distraction Osteogenesis via Endochondral Bone Formation

Kim JB, Lee DY, Seo SG, Kim EJ, Kim JH, Yoo WJ, Cho TJ, Choi IH

BACKGROUND: Distraction osteogenesis (DO) is a promising tool for bone and tissue regeneration. However, prolonged healing time remains a major problem. Various materials including cells, cytokines, and growth factors have...
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Four Flaps Technique for Neoumbilicoplasty

Lee YT, Kwon C, Rhee SC, Cho SH, Eo SR

The absence or disfigurement of the umbilicus is both cosmetically and psychologically distressing to patients. The goal of aesthetically pleasing umbilical reconstruction is to create a neoumbilicus with sufficient depth...
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Glomus Tumor of the Hand

Lee W, Kwon SB, Cho SH, Eo SR, Kwon C

BACKGROUND: Glomus tumors were first described by Wood in 1812 as painful subcutaneous tubercles. It is an uncommon benign neoplasm involving the glomus body, an apparatus that involves in thermoregulation...
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Pedicled Anterolateral Thigh Flaps for Reconstruction of Recurrent Trochanteric Pressure Ulcer

Bahk S, Rhee SC, Cho SH, Eo SR

The reconstruction of recurrent pressure sores is challenging due to a limited set of treatment options and a high risk of flap loss. Successful treatment requires scrupulous surgical planning and...
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