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A Case of Free-Floating Endolymph Particle Found during Transmastoid Posterior Semicircular Canal Occlusion for Intractable Posterior Canal Benign Paroxysmal Positional Vertigo

Park JS, Lee SH, Park YH, Choi JW

Benign paroxysmal positional vertigo (BPPV) is a common inner ear cause of vertigo, most of which can be treated by particle repositioning maneuver (PRM). However, in rare cases, positional vertigo...
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A Case of Congenital Sensorineural Hearing Loss with Multinodular Goiter

Park KH, Park JJ, Choi SM, Kwon SU

  • KMID: 2276401
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Apr;48(4):535-538.
Pendred syndrome is an autosomal recessive condition classically characterized by congenital deafness and goiter, and is the most common cause of hereditary deafness in Korea. It is caused by mutations...
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Persistent Positional Vertigo in a Patient with Sudden Sensorineural Hearing Loss: A Case Report

Kim YW, Shin JE, Lee YS, Kim CH

Because inner ear organs are interconnected through the endolymph and surrounding endolymphatic membrane, the patients with sudden sensorineural hearing loss (SSNHL) often complain of vertigo. In this study, we report...
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Morphological Changes of Endolymphatic Sac after Gentamicin Injection to Chick Embryo

Lee JH, Kim DY, Lee YK, Han GC, Ha JS, Cha HE

  • KMID: 1875133
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Sep;48(9):1091-1095.
BACKGROUND AND OBJECTIVES: Gentamicin, which is known to have potential toxic effect to the inner ear, causes functional disturbance by destroying the inner ear at a concentration above a certain...
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Meniere's Disease

Lee WS, Koo JW

Hydrops of the endolymphatic space in the inner ear deteriorates hearing and balance function. This idiopathic syndrome of endolymphatic hydrops is Meniere's disease and is characterized by episodic vertigo, fluctuating...
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Ménière's Disease and Electrophysiology

Kim SH

Inner ear is composed of cochlea, vestibule, and endolymphatic sac which are enclosed by thin layer of epithelial cells. The enclosed space is filled with fluid named as endolymph where...
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Expression of FGF-R and TGF-R in the Lateral Wall of the Guinea Pig

Lee BD, Kim SH, Ahn HY, Chang HS, Kang JW

  • KMID: 1886938
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 May;42(5):547-551.
BACKGROUND AND OBJECTIVES: The endolymph produced from cochlear lateral wall regulates fluid balance and maintains positive endocochlear potentials. Although many immunohistochemical studies on ion transport enzymes have been reported, their...
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Expression of Voltage-dependent Na+ Channels in the Albino Guinea Pig Cochlea

Lee SW, Lee SK, Cho NS, Song TH, Lee BD, Chang HS, Kang JW, Kim YJ

  • KMID: 2275619
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jan;44(1):15-20.
BACKGROUND AND OBJECTIVES: The endolymph produced from cochlear lateral wall regulates fluid and maintains positive endocochlear potential. Although many immunohistochemical studies of ion transport enzymes in the cochlear lateral wall...
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Incidence and Clinical Significance of Positional Downbeat Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo

Oh EH, Lee JH, Kim HJ, Choi SY, Choi KD, Choi JH

BACKGROUND AND PURPOSE: The aim of this study was to determine the incidence and clinical significance of positional downbeat nystagmus (pDBN) after treatment of posterior canal (PC) benign paroxysmal positional...
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The Effect of Antidiuretic Hormone on Ionic Currents of Strial Marginal Cells in Neonate Rate

Lee JH, Kim SJ, Kim J, Kim KW

  • KMID: 1886939
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 May;42(5):552-558.
BACKGROUND AND OBJECTIVES: Strial marginal cells are known to secrete K(+) into endolymph. Slowly activating, voltagede-pendent K(+) channels (I(sK) channels) have been identified in the apical membrane of these cells....
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The Role of Inflammatory Mediators in the Pathogenesis of Otitis Media and Sequelae

Juhn SK, Jung MK, Hoffman MD, Drew BR, Preciado D, Sausen NJ, Jung TT, Kim BH, Park SY, Lin J, Ondrey FG, Mains DR, Huang T

This review deals with the characteristics of various inflammatory mediators identified in the middle ear during otitis media and in cholesteatoma. The role of each inflammatory mediator in the pathogenesis...
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Immunohistochemical Localization of Na/K-APTase Subunit Isoforms in Rat Inner Ear

Kim HJ, Sohn JH, Lee SW, Kim BY, Ahn KY

  • KMID: 2040103
  • Korean J Anat.
  • 1999 Aug;32(4):583-591.
The endolymph and perilymph of the inner ear have unique ionic composition and electrical potential. It is widely accepted that normal auditory function depends on them and Na/K-ATPase plays a...
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Expression of Protein Kinase C Isotypes in the Albino Guniea Pig Cochlea

Lee BD, Choi JH, Kim HJ, Yu MS, Kim JW, Lee JH, Kim DW, Chang HS

  • KMID: 2276028
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Sep;46(9):733-736.
BACKGROUND AND OBJECTIVES: Protein kinase plays an important role in transmembrane signalling, which is modulated by cellular transduction by second messengers such as inositol-1, 4, 5-triphosphate (IP3), Diacylglycerol (DG), cAMP,...
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Relation between Stress-Related Hormone and Sudden Sensorineural Hearing Loss

Kang BS, Lee HS, Park JS, Bae KG, Lee BD, Lee JS

BACKGROUND AND OBJECTIVES: The plasma stress-related hormonal [cortisol, growth hormone, prolactin, antidiuretic hormone (ADH), adrenocorticotropic hormone (ACTH)] levels have been reported to be elevated in sudden sensorineural hearing loss (SSNHL)...
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Expression Patterns of KCNJ10 K+ Channel in the Cochlear Lateral Wall After Acoustic Trauma

Koo BS, Kim AY, Park JY, Lee SH, Kim JM, Kim YM, Rha KS, Park YH

  • KMID: 2276861
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Apr;51(4):312-318.
BACKGROUND AND OBJECTIVES: It is well known that noise exposure leads to the sensory hair cell loss and other neuronal damage in the cochlea. But recently it has been reported...
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Measurement of the Mechanical Deformation of Organ of Corti in a Model of Acute Endolymphatic Hydrops

Lee SH, Kalinec F

BACKGROUND AND OBJECTIVES: Endolymphatic hydrops has been considered as an important histologic substrate of Meniere's disease. A permanent displacement of basilar membrane (BM) by increased endolymphatic pressure has been thought...
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