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Clinical Evidence of Chemotherapy or Endocrine Therapy Maintenance in Patients with Metastatic Breast Cancer: Meta-Analysis of Randomized Clinical Trials and Propensity Score Matching of Multicenter Cohort Study

Ren W, Yu Y, Hong H, Wang Y, Gao Q, Chen Y, Chen P, Zhao J, Ou Q, Lin D, Fu T, Tan Y, Li C, Xie X, Ye G, Tang J, Yao H

Purpose This study aims to comprehensively evaluate the clinical efficacy of chemotherapy or endocrine therapy maintenance in metastatic breast cancer (MBC) patients. Materials and Methods The meta-analysis of randomized clinical trials...
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A Case of Non-Syndromic Dermal Hyperneury

Kwon HM, Jeong EH, Yim JE, Shin DH, Choi JS, Bae YK

  • KMID: 2532854
  • Korean J Dermatol.
  • 2022 Aug;60(7):459-460.
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Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)

Lee Jy, Kim SY, Jo KH, Mo EY, Kim ES, Kim HS, Han JH, Moon Sd

Background/Aims: Germline mutations of the rearranged during transfection (RET) gene cause multiple endocrine neoplasia type 2 (MEN2). About 85% of RET mutations in MEN2 occur in codon Cys634. The RET...
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KSNM60 in Nuclear Endocrinology: from the Beginning to the Future

Hong C, Jeong Y, Kim H, Ahn B

Nuclear endocrinology is the main ignitor for founding the Korean Society of Nuclear Medicine (KSNM) in the early 1960s by outstanding pioneering medical doctors. Management of thyroid diseases required nuclear...
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Association of Early Pubertal Onset in Female Rats With Inhalation of Lavender Oil

Kim YM, Lim HH

Background: Central precocious puberty (CPP) is caused by early activation of the hypothalamic–pituitary–gonadal axis but its major cause remains unclear. Studies have indicated an association between chronic environmental exposure to...
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Prader-Willi syndrome: an update on obesity and endocrine problems

Kim SJ, Cho SY, Jin DK

Prader-Willi syndrome (PWS) is a rare complex genetic disorder that results from a lack of expression of the paternally inherited chromosome 15q11-q13. PWS is characterized by hypotonia and feeding difficulty...
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Clinical Value of Serum Mitochondria-Inhibiting Substances in Assessing Renal Hazards: A Community-Based Prospective Study in Korea

Choi HS, Kim JT, Lee HK, Park WH, Kim Pak Y, Lee SW

Background: Mitochondrial dysfunction is strongly associated with several kidney diseases. However, no studies have evaluated the potential renal hazards of serum mitochondria-inhibiting substance (MIS) and aryl hydrocarbon receptor ligand (AhRL)...
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Endocrine comorbidities of pediatric obesity

Lee J, Kim JH

Pediatric obesity has become a serious public health issue. The prevalence of obesity in children and adolescents has increased worldwide and in Korea over several decades. Obese children are more...
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Application of robots in general surgery

Kim JK, Yang SY, Kim SH, Kim HI

Background: Application of robotic surgery in the field of general surgery has been increasing. This paper is an overview of the current uses and future perspectives of robotic surgery in...
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A Study on the Relationship between Fatigue, Psychosocial Stress, and Behavior that Reduces Endocrine Disrupting Chemicals Exposure in Infertile Males

Kim SJ, Choi SY

Purpose: This study aimed to identify the relationships between fatigue, psychosocial stress, and behavior of infertile males that reduces endocrine-disrupting chemical (EDC) exposure and to provide baseline data needed for...
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Implications of Tamoxifen Resistance in Palbociclib Efficacy for Patients with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Subgroup Analyses of KCSG-BR15-10 (YoungPEARL)

Lee J, Im SA, Kim GM, Jung KH, Kang SY, Park IH, Kim JH, Ahn HK, Park YH

Purpose YoungPEARL (KCSG-BR15-10) trial demonstrated a significant progression-free survival (PFS) benefit for premenopausal patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative (HR+/HER2–) metastatic breast cancer (MBC) for palbociclib plus...
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Nontraditional Risk Factors for Obesity in Modern Society

Han SJ, Lee SH

Overweight and obesity, which have rapidly increased around the world in recent years, are significant health problems. They can lead to various morbidities, including cardiovascular diseases, cerebrovascular diseases, type 2...
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Alterations of Kiss 1 receptor, GnRH receptor and nuclear receptors of the hypothalamopituitary-ovarian axis following low dose bisphenol-A exposure in Wistar rats

Kadir ER, Imam A, Olajide OJ, Ajao MS

Bisphenol A is a chemical used primarily as a monomer in the production of polycarbonate plastics and epoxy resins. It is a synthetic chemical compound that is produced in billions...
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Pediatric Endocrinology of Post-Pandemic Era

Seo JY

The COVID-19 pandemic has brought about significant changes in the global health and medical environment. In order to prevent viral transmission, governments implemented strong social distancing, even lockdowns. The closure...
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DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption

Kim MJ, Kim HH, Song YS, Kim OH, Choi K, Kim S, Oh BC, Park YJ

Background: Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on...
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Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective

Winz C, Suh N

Endocrine disruptors, such as bisphenol A (BPA), have become more frequently present in the environment as contaminants, especially in industrialized countries. Long-term effects of these environmental contaminants in humans are...
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Best Achievements in Translational and Basic Thyroidology in 2020

Cho SW, Park YJ

This review discusses articles published in 2020 that presented noteworthy achievements in translational and basic thyroidology. Previously unresolved questions about thyroid hormone receptor actions and signaling mechanisms were answered using...
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Development and Effect of a Behavior Program for Reducing Exposure to Endocrine Disrupting Chemicals in Unmarried Women

Kim HJ, Choi SY

Purpose: This study was conducted to develop a behavior program for reducing exposure to endocrine disrupting chemicals (EDCs), thereby to improve perceived benefits and self-efficacy as well as reduce the...
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The Association of Ovarian Reserve with Exposure to Bisphenol A and Phthalate in Reproductive-aged Women

Park SY, Jeon JH, Jeong K, Chung HW, Lee H, Sung YA, Ye S, Ha EH

Background: Exposure to endocrine disrupting chemicals (EDCs) that influence the hormonal and homeostatic systems is known to be associated with gynecologic health risks in many countries. In this study, we...
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Acquired Hypopituitarism in Diamond-Blackfan Anemia

Yun JY, Choi JE, Kim HS, Ryu KH

Diamond-Blackfan anemia (DBA) is a rare, inherited bone marrow failure syndrome that manifests as anemia in early infancy. Blood transfusion is a critical factor for survival. However, blood transfusions can...
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