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Association of Proteinuria with Urinary Concentration Defect in Puromycin Aminonucleoside Nephrosis

Jo CH, Kim S, Kim GH

Background: Puromycin aminonucleoside (PA) can induce nephrotic syndrome in rats, and proteinuria is an important mediator of tubulointerstitial injury in glomerulopathy. We assumed that glomerular proteinuria may affect tubular function,...
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The Effects of Oral Atenolol or Enalapril Premedication on Blood Loss and Hypotensive Anesthesia in Orthognathic Surgery

Kim NY, Yoo YC, Chun DH, Lee HM, Jung YS, Bai SJ

PURPOSE: The aim of this study was to evaluate the effects of premedication with oral atenolol or enalapril, in combination with remifentanil under sevoflurane anesthesia, on intraoperative blood loss by...
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Comparison of Inhibitory Effects between Enalapril and Losartan on Adrenal Catecholamine Secretion

Lim HJ, Koh YY, Lim DY

BACKGROUND: The present study was attempted to compare enalapril, an angiotensin-converting enzyme inhibitor with losartan an angiotensin II (Ang II) receptor blocker in the inhibitory effects on the secretion of...
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Antioxidant Effect of Captopril and Enalapril on Reactive Oxygen Species-Induced Endothelial Dysfunction in the Rabbit Abdominal Aorta

Kim JH, Kim H, Kim YH, Chung WS, Suh JK, Kim SJ

BACKGROUND: Reactive oxygen species (ROS) are known to be related to cardiovascular diseases. Many studies have demonstrated that angiotensin-converting enzyme inhibitors have beneficial effects against ROS. We investigated the antioxidant...
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The Effect of Enalapril and Carvedilol on Left Ventricular Dysfunction in Middle Childhood and Adolescent Patients With Muscular Dystrophy

Kwon HW, Kwon BS, Kim GB, Chae JH, Park JD, Bae EJ, Noh CI

BACKGROUND AND OBJECTIVES: In Duchenne and Becker muscular dystrophies, cardiac function deteriorates with time resulting in heart failure which is often fatal. We prospectively evaluated the effect of enalapril and...
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Angiotensin-Converting Enzyme Inhibitors and Angioedema

Sanchez-Borges M, Gonzalez-Aveledo LA

PURPOSE: To investigate the incidence and clinical characteristics of angioedema associated with the use of angiotensin-converting enzyme inhibitors (ACEIs) in an outpatient allergy department. METHODS: A retrospective review of medical records...
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Steroid and enalapril therapy: possible cause of toxic epidermal necrolysis

Kim DW, Jung DE, Koo JW

Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN is characterized by the sudden onset of extensive necrosis in the epidermis and frequent mucous membrane...
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Effect of Enalapril or Lovastatin on Tubulointerstitial Injury Induced by Protein-overload Proteinuria in Rats

Chung SJ, Chung JG, Yang WS, Kim SB, Park SK, Lee SK, Park JS

  • KMID: 1989745
  • Korean J Nephrol.
  • 2001 May;20(3):393-402.
BACKGROUND: Previous studies have demonstrated that enalapril or lovastatin seems to ameliorate the renal injury in several animal models with glomerulonephritis. The aim of this study was to examine whether...
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Individual or combined effects of enalapril and verapamil on chronic cyclosporine nephrotoxicity in rats

Lee SK, Park JY, Yu ES, Yang WS, Kim SB, Park SK, Park JS

Previous studies have demonstrated that enalapril and verapamil seem to attenuate the cyclosporine nephrotoxicity. However, the mechanisms have not been completely understood, especially on molecular events. The aim of this...
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Contractile and relaxing responses of the contralateral renal artery in renovascular hypertensive rats

Kim SJ, Lee EY, Choi SO, Kang NK, Lee HJ, Han BG, Kim JS, Kim MH, Karl EH, Song KH

  • KMID: 2143095
  • Korean J Med.
  • 1999 Nov;57(5):925-932.
Although only a small portion of patients with hypertension have renal hypertension, studies regarding renal hypertension may provide insight into the pathophysiology of essential hypertension. An increased vascular reactivity to vasoconstrictor substances...
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The Effects of Angiotensin Converting Enzyme Inhibitor on Progressive Glomerular Sclerosis

Park MO, Kim YJ, Oh HK, Lee CH, Hyun BH, Kwak JS

  • KMID: 2275700
  • Korean J Pathol.
  • 1998 Dec;32(12):1058-1065.
Almost all advanced glomerular diseases have glomerular sclerotic changes to varying degrees whatever causes their primary glomerular disease are. Pathogenesis of these sclerosis has been thought of as the hyperfiltration...
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Effects of angiotensin converting enzyme inhibition on gene expression of the renin-angiotensin system in rats

Lee YR, Lee MY, Kim WJ, Lee WJ

  • KMID: 2071836
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):771-778.
To investigate interaction of angiotensin converting enzyme (ACE) inhibitor with local tissue renin-angiotensin system (RAS), changes in gene expression of the RAS components in various tissues in response to chronic administration of an...
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The Effect of Enalapril on the Peak Rates of Left Ventricular Wall Movement in Patients with Dilated Cardiomyopathy

Kim CW, Jung YS, Lee KJ, Kwak MH, Kim KM, Kim TH, Kim CJ, Ryu WS, Ryoo UH

  • KMID: 2080506
  • Korean J Med.
  • 1997 May;52(5):617-623.
OBJECTIVE: Angiotensin-converting enzyme inhibitors have been shown to improve survival in patients with congestive heart failure. To evaluate the efficacy of enalapril in patients with dilated cardiomyopathy during concurrent treatment...
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Effect of Enalapril Treatment on Erythrocytosis after Renal Transplantation

Jeon GH, Park SK, Kim SW, Rhee SR

  • KMID: 2095221
  • J Korean Surg Soc.
  • 1997 Apr;52(4):572-579.
Posttransplant erythrocytosis (PTE) is a common complication of renal transplantation. It afflicts 5-15 % of renal transplant recipients with good renal function and is associated with an increased incidence of...
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Effect of Enalpril on LVH and LV Performance in Essential Hypertension

Lee DC

BACKGROUND: Left ventricular hypertrophy(LVH) is the independent poor prognostic factor in hypertensives. But, it is uncertain that the reduction of LVH by antihypertensives therapy will improve the prognosis of hypertensive...
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Studies on the structural changes of aortic media and its repairing effect by enalapril in spontaneously hypertensive rats

Hong SP, Chung CH

BACKGROUND: It has been known that arteries of hypertensive animals and patients are generally thicker and more rigid than those of normal subjects, resulting from the morphological changes induced by...
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The Effect of Enalapril in the Patients with the Chronic Severe Congestive Heart Failure

Kim JS, Kim MH, Kim JS, Shin JM, Suh YZ, Son JW, Sung MS

ACE inhibitiors have been recently used to treat the chronic congestive heart failure after the use of the antihypertensive agents.The enalapril was added to the chronic congestive heart failure patients...
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Influence of Enalapril on Blood Pressure in Spontaneously Hypertensive Rats

Huh HH, Son UD, Kim CY, Bae JD

We aimed to evaluate the long term trantment of enalapril on the vascular response in the isolated aorta, and in anesthetized or pithed spontaneously hypertensive rats(SHR). In the isolated aorta,...
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Electron Microscopic Study of Enalapril Effect on Left Ventricular Hypertrophy in Spontaneously Hypertensive Rat

Lee BH, Kim JH, Lim HK, Lee CK, Choi IG

Left ventricular hypertrophy is a compensatory response to hemodynamic overload secondary to an increased systemic resistance. This increase, however, is not the only cause of hypertrophy, and there are other...
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Clinical Observation on Antihypertensive Effects of Enalapril

Kwak CH, Chung JH, Lee HW, Chae SC, Jun JE, Park WH

To observe the antihypertensive effects of the angiotensin-converting enzyme inhibitor, enalapril, a daily average dosage of 20mg was administred to 38 patients with essential hypertension for 4 weeks. Changes in...
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