- Role of breast regression protein-39/YKL-40 in asthma and allergic responses
-
Lee CG, Elias JA
- KMID: 2260415
- Allergy Asthma Immunol Res.
- 2010 Jan;2(1):20-27.
- doi: 10.4168/aair.2010.2.1.20
BRP-39 and its human homolog YKL-40 have been regarded as a prototype of chitinase-like proteins (CLP) in mammals. Exaggerated levels of YKL-40 protein and/or mRNA have been noted in a... -
- CITED
-
- Close
- SHARE
-
- Close
- Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model
-
Mo Y, Kim Y, Bang JY, Jung J, Lee CG, Elias JA, Kang HR
- KMID: 2536267
- Immune Netw.
- 2022 Oct;22(5):e40.
- doi: 10.4110/in.2022.22.e40
Mesenchymal stem cells (MSCs) are attractive alternatives to conventional anti-asthmatic drugs for severe asthma. Mechanisms underlying the anti-asthmatic effects of MSCs have not yet been elucidated. This study evaluated the... -
- CITED
-
- Close
- SHARE
-
- Close
- Modifiers of TGF-beta1 effector function as novel therapeutic targets of pulmonary fibrosis
-
Lee CM, Park JW, Cho WK, Zhou Y, Han B, Yoon PO, Chae J, Elias JA, Lee CG
- KMID: 1792051
- Korean J Intern Med.
- 2014 May;29(3):281-290.
- doi: 10.3904/kjim.2014.29.3.281
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-beta1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-gamma
-
Lee BJ, Moon HG, Shin TS, Jeon SG, Lee EY, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104386
- Exp Mol Med.
- 2011 Apr;43(4):169-178.
- doi: 10.3858/emm.2011.43.4.018
Recent clinical evidence indicates that the non-eosinophilic subtype of severe asthma is characterized by fixed airway obstruction, which may be related to emphysema. Transgenic studies have demonstrated that high levels... -
- CITED
-
- Close
- SHARE
-
- Close
- IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model
-
Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104380
- Exp Mol Med.
- 2010 Aug;42(8):533-546.
- doi: 10.3858/emm.2010.42.8.054
IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream... -
- CITED
-
- Close
- SHARE
-
- Close
