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Capsaicin-Induced Apoptosis in MBT-2 Murine Bladder Tumor Cells and Bladder Wall Penetration Effect of the Nano-Encapsulated Capsaicin in Rabbit

Cho SJ, Moon HW, Bae WJ, Park YH, Ha US, Hong SH, Kim SW, Lee JY

PURPOSE: In this study, we attempted to characterize capsaicin's effects with regard to the apoptosis of murine bladder cancer cells (MBT-2) as well as the pharmacodynamics of nano-encapsulated capsaicin formulation...
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A Case of Salivary-Type Amylase-Producing Multiple Myeloma Presenting as Mediastinal Plasmacytoma and Myelomatous Pleural Effusion

Ok SJ, Kim IS, Lee EY, Kang JE, Lee SM, Song MK

No abstract available.
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Induction of apoptosis by a hexane extract of aged black garlic in the human leukemic U937 cells

Park C, Park S, Chung YH, Kim GY, Choi YW, Kim BW, Choi YH

  • KMID: 2313720
  • Nutr Res Pract.
  • 2014 Apr;8(2):132-137.
BACKGROUND/OBJECTIVES: In this study, the apoptogenic activity and mechanisms of cell death induced by hexane extract of aged black garlic (HEABG) were investigated in human leukemic U937 cells. MATERIALS/METHODS: Cytotoxicity was...
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The expressions of stem cell markers: Oct4, Nanog, Sox2, nucleostemin, Bmi, Zfx, Tcl1, Tbx3, Dppa4, and Esrrb in bladder, colon, and prostate cancer, and certain cancer cell lines

Amini S, Fathi F, Mobalegi J, Sofimajidpour H, Ghadimi T

Uncontrolled self-renewal plays a direct function in the progression of different types of carcinomas. The same molecular pathway that manages self-renewal in normal stem cells also seems to manage cancer...
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In Vitro and In Vivo Imaging of Prostate Cancer Angiogenesis Using Anti-Vascular Endothelial Growth Factor Receptor 2 Antibody-Conjugated Quantum Dot

Kwon H, Lee J, Song R, Hwang SI, Lee J, Kim YH, Lee HJ

OBJECTIVE: Authors aimed to determine the targeting ability of vascular endothelial growth factor receptor 2 (VEGFR2)-conjugated quantum dots (QDs) in vitro, and apply it for a xenograft prostate cancer mouse...
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Cholestasis Causes Discrepancy in HDL-Cholesterol Levels Measured Using Various Methods

Kim S, Chun S, Lee W, Kim GS, Min WK

  • KMID: 2312202
  • Lab Med Online.
  • 2012 Jul;2(3):174-178.
Herein, we report a case in which cholestasis caused discrepancy in high-density lipoprotein (HDL)-cholesterol levels measured using various methods. The discrepancy in HDL-cholesterol level originated from the abnormal increase in...
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Appraisal of Antihyperlipidemic Activities of Lentinus lepideus in Hypercholesterolemic Rats

Yoon KN, Lee JS, Kim HY, Lee KR, Shin PG, Cheong JC, Yoo YB, Alam N, Ha TM, Lee TS

  • KMID: 2312655
  • Mycobiology.
  • 2011 Dec;39(4):283-289.
The wild edible mushroom, Lentinus lepideus has recently been cultivated for commercial use in Korea. While the mushroom has been widely used for nutritional and medicinal purposes, the possible anti-hyperlipidemic...
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Antihyperlipidemic Effect of Dietary Lentinus edodes on Plasma, Feces and Hepatic Tissues in Hypercholesterolemic Rats

Yoon KN, Alam N, Lee JS, Cho HJ, Kim HY, Shim MJ, Lee MW, Lee TS

  • KMID: 2312622
  • Mycobiology.
  • 2011 Jun;39(2):96-102.
We investigated diet supplementation with shiitake mushroom fruiting bodies on biochemical and histological changes in hypercholesterolemic rats. Six-wk old female Sprague-Dawley albino rats were divided into three groups of 10...
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Hypolipidemic Activities of Dietary Pleurotus ostreatus in Hypercholesterolemic Rats

Alam N, Yoon KN, Lee TS, Lee UY

  • KMID: 2312610
  • Mycobiology.
  • 2011 Mar;39(1):45-51.
This work was conducted to investigate dietary supplementation of oyster mushroom fruiting bodies on biochemical and histological changes in hyper and normocholesterolemic rats. Six-week old female Sprague-Dawley albino rats were...
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Effects of Delay in the Snap Freezing of Colorectal Cancer Tissues on the Quality of DNA and RNA

Hong SH, Baek HA, Jang KY, Chung MJ, Moon WS, Kang MJ, Lee DG, Park HS

PURPOSE: The success of basic molecular research using biospecimens strongly depends on the quality of the specimen. In this study, we evaluated the effects of delayed freezing time on the...
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Evaluation of a Multiplex PCR Kit Used for Detecting Y Chromosome Microdeletions

Park MY, Kang HM, Hwang SH, Park HJ, Park NC, Choi KU, Kim HH, Chang CL, Lee EY

BACKGROUND: In addition to Klinefelter's syndrome, microdeletion of Yq is the most common genetic cause of male infertility; 15% of azoospermic or 5-10% of oligozoospermic males have Yq deletions. We...
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Plasmid profiling of Flavobacterium psychrophilum isolates from ayu (Plecoglossus altivelis altivelis) and other fish species in Japan

Kim JH, Gomez DK, Nakai T, Park SC

In order to evaluate the genetic variability of the causative agent of cold water disease (CWD), plasmid profiling was used to characterize Flavobacterium (F.) psychrophilum isolates (n = 169). Size...
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The Clinical Value of Modified Low Density Lipoprotein-Cholesterol in Patients Who Underwent Percutaneous Coronary Intervention

Yoon NS, Jeong MH, Kim YA, Lee WS, Hwang SH, Lee SR, Hong SN, Kim KH, Park HW, Kim JH, Ahn YK, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: It is well known that atherosclerosis is characterized by chronic inflammation of an injured intima and the pathological processes are initiated by an accumulation of morphologically distinct,...
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A Case of Multiple Myeloma Showing Marked Differences in Serum IgG Levels between Protein Electrophoresis and Turbidimetry

Shin JW, Park R, Choi TY

We report a case of multiple myeloma showing marked differences in serum Immunoglobulin G (IgG) levels between serum protein electrophoresis and turbidimetry. A 47-yr old man was admitted to our...
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Serum Lipid Analysis Using Biphasic Electrophoresis

Park JY, Choi HW, Lee JS, Cho D, Shin MG, Shin JH, Suh SP, Ryang DW

  • KMID: 2200647
  • J Lab Med Qual Assur.
  • 2008 Jun;30(1):201-207.
BACKGROUND: Recently biphasic agarose gel electrophoresis method using Chol/Trig ComboTM for simultaneous detection of cholesterol and triglyceride on lipoprotein fractions has been developed to facilitate the classification and interpretation of...
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Establishment and Application of Molecular Genetic Techniques for Preimplantation Genetic Diagnosis of Osteogenesis Imperfecta

Kim MJ, Lee HS, Choi HW, Lim CK, Cho JW, Kim JY, Song IO, Kang IS

  • KMID: 1986918
  • Korean J Reprod Med.
  • 2008 Jun;35(2):99-110.
OBJECTIVES: Preimplantation genetic diagnosis (PGD) has become an assisted reproductive technique for couples carrying genetic conditions that may affect their offspring. Osteogenesis imperfecta (OI) is an autosomal dominant disorder of...
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Membrane transducing activity of recombinant Hoxc8 protein and its possible application as a gene delivery vector

Kim ES, Kang M, Park HW, Kim MH

In order to examine whether the Hoxc8 protein can deliver nucleic acid into mammalian cells, we designed several Hoxc8-derived recombinant proteins to be synthesized as glutathione S-transferase (GST) fused forms...
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Enhancement of Arsenic Trioxide (As2O3)-Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y Cells

Kim DW, Ahan SH, Kim TY

OBJECTIVE: Arsenic trioxide (As2O3) has been used as an anticancer agent in traditional Chinese medicine for thousand years and berberine is an isoquinoline alkaloid present that has indicated significant antimicrobial...
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Studies on the Development of Viral Detection Markers for the Quality Control of Blood

Kim Y, Lee JH, Kim Y

According to the serological screening methods of antigen-antibody reaction such as ELISA, it has been known that the complete detection of viral infections of HBV, HCV, and HIV-1 viruses in...
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Identification of Candida Species by Multiplex Polymerase Chain Reaction

Lee MK, Kim HR, Lee YJ

  • KMID: 2224724
  • Korean J Clin Microbiol.
  • 2006 Oct;9(2):119-124.
BACKGROUND: Polymerase chain reacation (PCR)-based methods have been described for rapid detection and identification of Candida spp. Multiplex PCR assay was developed using internal transcribed spacers and topoisomerase II gene...
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