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Role of n-3 long-chain polyunsaturated fatty acids in human nutrition and health: review of recent studies and recommendations

Dael PV

Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to...
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Best Achievements in Clinical Medicine in Diabetes and Dyslipidemia in 2020

Rhee EJ, Kim MK, Lee WY

Over the last two decades, our understanding of diabetes and treatment strategies have evolved tremendously, from scientific, mechanistic, and human perspectives. The categories of anti-diabetic medications expanded from a few...
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G Protein–Coupled Receptor 30 Mediates the Anticancer Effects Induced by Eicosapentaenoic Acid in Ovarian Cancer Cells

Zhao Y, Zhao MF, Yang ML, Wu TY, Xu CJ, Wang JM, Li CJ, Li X

Purpose While numerous epidemiological studies have indicated that omega-3 polyunsaturated fatty acids have anticancer properties in various cancers, the effects and mechanisms of eicosapentaenoic acid (EPA) in ovarian cancer cell growth...
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Omega 3 Fatty Acids and COVID-19:A Comprehensive Review

Hathaway III D, Pandav K, Patel M, Riva-Moscoso A, Singh BM, Patel A, Chi Min Z, Singh-Makkar S, Khawar Sana M, Sanchez-Dopazo R, Desir R, Mourad Fahem MM, Manella S, Rodriguez I, Alvarez A, Abreu R

The rapid international spread of severe acute respiratory syndrome coronavirus 2 responsible for coronavirus disease 2019 (COVID-19) has posed a global health emergency in 2020. It has affected over 52...
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Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial

Golzari MH, Javanbakht MH, Ghaedi E, Mohammadi , Djalali M

Type 2 diabetes mellitus (T2DM) is recognized as one of the most prevalent metabolic diseases, and it is mostly associated with oxidative stress, atherosclerosis and dyslipidemia. Paraoxonase 2 (PON2) due...
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Low Plasma Proportion of Omega 3-Polyunsaturated Fatty Acids Predicts Poor Outcome in Acute Non-Cardiogenic Ischemic Stroke Patients

Song TJ, Cho HJ, Chang Y, Choi K, Jung AR, Youn M, Shin MJ, Kim YJ

BACKGROUND AND PURPOSE: Alterations in blood fatty acid (FA) composition are associated with cardiovascular diseases. We investigated whether plasma FA composition was related to stroke severity and functional outcome in...
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Omega-3 Index as a Risk Factor for Cardiovascular Disease and Its Application to Korean Population

Park Y

  • KMID: 1461009
  • Korean J Obes.
  • 2010 Mar;19(1):1-8.
Of all known dietary factors, long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) may be the most protective against death from cardiovascular disease. Evidence continues to accrue for benefits...
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Increased Inflammation, Reduced Plasma Phospholipid Eicosapentaenoic Acid and Reduced Antioxidant Potential of Treated Hypertensive Patients with Metabolic Syndrome

Shin MJ, Shim E, Kang B, Park S, Lee SH, Shim CY, Park E, Chung N

PURPOSE: In the present study, we tested whether the presence of metabolic syndrome (MetS) would worsen the features of inflammation, plasma omega 3 fatty acid levels and antioxidant potential in...
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Effect of Eicosapentaenoic Acid on Endothelial Cell-U937 Cell Adhesion

Chae SC, Kim EJ, Lim HJ, Cheong ER, Cho YK, Jun JE, Park WH

BACKGROUND: Epidemiological studies have shown correlation between low incidence of coronary heart disease and high consumption of fish products. It has been suggested that this may be due to the...
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