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Selectins: functional importance as cell adhesion molecule in immune system

Noh Y, Cho D, Ko H, Lim D, Chai HH

Selectins are cell membrane glycoproteins that recognize specific glycoconjugates expressed on the surface of cells. Then, selectins adjust cell-cell interactions that are important in inflammation, hemostasis and cancer metastasis. Selectins...
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Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors

Kim MJ, Kim T, Suh GJ, Kwon WY, Kim KS, Jung YS, Ko JI, Shin SM, Lee AR

OBJECTIVE: This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and...
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The effect of mesenchymal stem cell use on intra-abdominal adhesions in a rat model

Karaca G, Pehlivanli F, Aydin O, Altunkaya , Uzun H, Niyaz M, Özden H, Bulut H

PURPOSE: Intra-abdominal adhesions (IAA) are among the most frequently seen pathologies in general surgery practice with an increased morbidity and mortality. In the present study, we investigated the effect of...
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Histological and Biochemical Comparisons between Right Atrium and Left Atrium in Patients with Mitral Valvular Atrial Fibrillation

Park JH, Lee JS, Ko YG, Lee SH, Lee BS, Kang SM, Chang BC, Pak HN

BACKGROUND AND OBJECTIVES: It has been known that the dominant driver of atrial fibrillation (AF) exists in the left atrium (LA) and the incidence of systemic thromboembolism is higher than...
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Levels of Serum Soluble P-Selectin and E-Selectin in Psoriatic Patients

Ataseven A, Ataseven H, Ozturk P, Ozdemir M, Kesli R

No abstract available.
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Ginsenoside Rg2 Inhibits Lipopolysaccharide-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell

Cho YS, Kim CH, Ha TS, Lee SJ, Ahn HY

Vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), P- and E-selectin play a pivotal role for initiation of atherosclerosis. Ginsenoside, a class of steroid glycosides, is abundant...
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Expression of Intercellular Adhesion Molecule-1 and E-Selectin in Gastric Cancer and Their Clinical Significance

Jung WC, Jang YJ, Kim JH, Park SS, Park SH, Kim SJ, Mok YJ, Kim CS

  • KMID: 2372441
  • J Gastric Cancer.
  • 2012 Sep;12(3):140-148.
PURPOSE: Among cell adhesion molecules, serum levels of intercellular adhesion molecule-1 and E-selectin are known to be correlated with the metastatic potential of gastric cancer. In the present study, the...
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Fusobacterium nucleatum GroEL signaling via Toll-like receptor 4 in human microvascular endothelial cells

Lee HR, Choi BK

  • KMID: 1436486
  • Int J Oral Biol.
  • 2012 Sep;37(3):130-136.
The GroEL heat-shock protein from Fusobacterium nucleatum, a periodontopathogen, activates risk factors for atherosclerosis in human microvascular endothelial cells (HMEC-1) and ApoE-/- mice. In this study, we analyzed the signaling...
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Blood Level of Soluble CD30 and Soluble E-Selectin in Allergic Rhinitis Patients

Jun KH, Jeong HM, Choi SH, Lee JH

  • KMID: 2297592
  • J Rhinol.
  • 2011 Nov;18(2):112-115.
BACKGROUND AND OBJECTIVES: Blood levels of soluble CD30 and soluble E-selectin are related to allergic diseases such as atopic dermatitis or asthma. However, these levels have not been well investigated...
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Morphine Attenuates Endothelial Cell Adhesion Molecules Induced by the Supernatant of LPS-Stimulated Colon Cancer Cells

Min TJ, Park SH, Ji YH, Lee YS, Kim TW, Kim JH, Kim WY, Park YC

A large reservoir of bacterial lipopolysaccharide (LPS) is available in the colon and this could promote colon cancer metastasis by enhancing tumor cell adhesion, intravasation, and extravasation. Furthermore, adhesion molecules...
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Effect of Cyclosporine on Peripheral Blood and Lesional Skin in Psoriatic Patients

Chang SE, Yun WJ, Yoon GS, Choi JH, Kim BS, Hong SJ

BACKGROUND: Cyclosporine effectively suppresses immune responses and inhibits skin homing T cell responses in psoriasis. E-selectin is known to be up-regulated on vascular endothelium of inflammatory skin lesions such as...
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The Expression of the Adhesion Molecules on Interfacial Membrane fromthe Aseptically Loosened Failed Femoral Stems in Revisional Hip Arthroplasty

Lee SH, Hwang JH, Kim DW, Kim BK, Jeong HW

PURPOSE: To clarify the relationship between aseptic loosening of hip arthroplasty and adhesion molecules on interfacial membrane from revisional hip arthroplasty. MATERIALS AND METHODS: We studied 26 revisional total hip arthroplasties...
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Randomized, Open Label, Multicenter Clinical Trial about the Effect of Cilazapril on Vascular Endothelial Function in Patients with Type 2 Diabetes Combined with Hypertension

Rhee SY, Woo JT, Baik SH, Lee HW, Lee IK, Kim HS, Lee MK, Shong MH, Cho CG, Park BH, Cha BS, Kim YS

  • KMID: 2331794
  • J Korean Diabetes Assoc.
  • 2006 Nov;30(6):450-458.
BACKGROUND: The angiotensin converting enzyme inhibitor (ACEi) improves the vascular endothelial cell function and has a better clinical outcome by decreasing the LDL cholesterol oxidation, hypercoagulability, oxidative stress and improving...
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The Change of Serum Soluble E-selectin in Kawasaki Disease

Jeong JH, Cho EY, Lim JW, Cheon EJ, Ko KO, Lee KI

  • KMID: 2278630
  • Korean J Pediatr.
  • 2005 May;48(5):539-544.
PURPOSE: The aim of this study was to investigate the pathophysiologic role of serum E-selectin, vascular endothelial growth factor(VEGF)-induced cell adhesion mollecule in Kawasaki disease(KD) and to look for the...
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The Limited Immune Modulatory Effect of Early Escharectomy on Adhesion Molecules in Major Burn Patients

Kwon JE, Lee SY, Oh KI, Kim TW, Kwak IS, Han TH, Kim KM

BACKGROUND: Early escharectomy has been shown to improve the survival rates and the treatment outcomes of major burn patients. However, its exact mechanism, especially in terms of the human...
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Enhanced Expression of Cell Adhesion Molecules in the Aorta of Diabetic Mice is Mediated by gp91phox-derived Superoxide

Yun MR, Kim JJ, Lee SM, Heo HJ, Bae SS, Kim CD

  • KMID: 2285317
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):109-115.
Endothelial activation and subsequent recruitment of inflammatory cells are important steps in atherogenesis. The increased levels of cell adhesion molecules (CAM) have been identified in diabetic vasculatures, but the underlying...
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Maternal Serum Levels of VCAM-1, ICAM-1 and E-selectin in Preeclampsia

Kim SY, Ryu HM, Yang JH, Kim MY, Ahn HK, Lim HJ, Shin JS, Woo HJ, Park SY, Kim YM, Kim JW, Cho EH

Endothelial dysfunction is thought to be a central pathogenic feature in preeclampsia on the basis of elevated adhesion molecules. The aim of the present study was to compare the levels...
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Angiotensin Converting Enzyme Gene Insertion/Deletion Polymorphism and E-selectin S128R Polymorphism in Peripheral Atherosclerotic Occlusive Disease

Jeong GO, Kwon JN, Park DE, Kim JJ, Moon HB, So BJ

  • KMID: 2096178
  • J Korean Surg Soc.
  • 2004 Jun;66(6):508-513.
PURPOSE: Studies concerning the relationship between gene polymorphisms and potentially implicated cardiovascular disease have produced conflicting findings, in part due to differences in ethnic background between populations. These led us...
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A study on the Relationship of the Severity of Psoriasis, Serum Soluble E-selectin, MCP-1 and RANTES

Park JH, Kim NI

  • KMID: 2302939
  • Korean J Dermatol.
  • 2004 Feb;42(2):138-144.
BACKGROUND: Psoriasis is a chronic skin disease characterized histologically by prominent keratinocyte hyperplasia and an early inflammatory cell infiltrate. However, the pathogenesis is not fully understood yet. Recently, the evidence...
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Mononuclear Cells Induce E-selectin Gene Expression in Porcine Endothelial Cells

Cha YJ, Chae SL, Kim CH

  • KMID: 2252404
  • Korean J Hematol.
  • 2003 Aug;38(3):183-187.
BACKGROUND: E-selectin, a cell adhesion molecule for most leukocytes, is known to be expressed exclusively on the cytokine-stimulated endothelial cells (ECs). E-selectin is involved in the adhesion of neutrophils, monocytes...
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